5,043,733 research outputs found

    Spaces In, Outside Of, and Between

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    My practice involves leveraging analog and digital techniques from many disciplines, but especially graphic design, craft/material studies, and sculpture. I embrace reproduction and repetition as both tools and means to visualize what is often unseen, and to recognize not only what is made, but what supports making— from the straightforward and immediate to the complex and conceptual

    Outside-in disk evolution in the LMC

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    From the analysis of the color-magnitude diagrams and color functions of four wide LMC fields located from ~2 to 6 kpc from the kinematic center of the LMC we present evidence that, while the oldest population is coeval in all fields, the age of the youngest component of the dominant stellar population gradually increases with galactocentric distance, from currently active star formation in a field at 2.3 deg, to 100 Myr, 0.8 Gyr, and 1.5 Gyr in fields at 4.0 deg, 5.5 deg, and 7.1 deg, respectively. This outside-in quenching of the star formation in the LMC disk is correlated with the decreasing HI column density (which is < 2x 10^{20} cm^{-2} in the two outermost fields with little or no current star formation. Other work in the literature hints at similar behavior in the stellar populations of irregular galaxies, and in M33. This is observational evidence against the inside-out disk formation scenario in low-mass spirals and irregular galaxies. Alternatively, it could be that the age distribution with radius results from interplay between the evolution with time of the star-forming area of the LMC and the subsequent outward migration of the stars.Comment: 6 pages, 2 figures, ApJ Letters, in pres

    The ``Outside-In'' Outburst of HT Cassiopeiae

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    We present results from photometric observations of the dwarf nova system HT Cas during the eruption of November 1995. The data include the first two--colour observations of an eclipse on the rise to outburst. They show that during the rise to outburst the disc deviates significantly from steady state models, but the inclusion of an inner-disc truncation radius of about 4 RwdR_{wd} and a ``flared'' disc of semi-opening angle of 1010^{\circ} produces acceptable fits. The disc is found to have expanded at the start of the outburst to about 0.41RL10.41R_{L1}, as compared to quiescent measurements. The accretion disc then gradually decreases in radius reaching <0.32RL1<0.32R_{L1} during the last stages of the eruption. Quiescent eclipses were also observed prior to and after the eruption and a revised ephemeris is calculated.Comment: 9 pages, 11 figures, to appear in MNRA

    Engaging Outside Counsel in Transactional Law Clinics

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    This article examines the plurality of objectives and methods by which transactional law clinics collaborate with outside attorneys to competently represent their organizational clients on a wide range of legal issues. Some transactional law clinics rely on outside counsel as informal legal advisors or consultants; others collaborate with outside counsel for the development of community projects or referral of legal work; many transactional law clinics engage outside counsel as “local counsel” when assisting a client in other jurisdictions or internationally; still others engage outside counsel more formally to assist in student supervision of client work. For some, the idea of a clinic working with outside counsel poses a credible threat to clinical pedagogy, clinical faculty status, and the permanent integration of clinics into the law school curriculum. To others, collaborating with outside counsel is a part of everyday client representation, and may be necessary for ethical and professional responsibility reasons. While identifying and discussing the import of these concerns, this article asserts the benefits of collaborating with outside attorneys for law school clinical programs and proposes a framework for deciding whether and how to collaborate with outside attorneys. Specifically, this article sets forth a deliberate and systematic decision-making process for the clinical law professor’s use. The decision-making process proposed is context-specific and dependent on the objectives of the clinical law professor. This article further recommends proactive steps that a clinical law professor can take to facilitate the clinical law professor’s objectives if she decides to engage outside counsel, such as entering into a Memorandum of Understanding to solidify roles and responsibilities of all parties involved in the collaboration. While this article examines collaboration with outside counsel primarily through the lens of transactional law based clinical programs, our discussion provides helpful guidance to law school clinical programs generally

    "Outside and In: Hegel on natural history"

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    The relation between nature and spirit in Hegel is not as simple as slogans such as "nature has no history" or a simple interior/exterior dichotonmy would suggest

    Randomly Available Outside Options in Bargaining

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    We consider an extension of the standard Rubinstein model where both players are randomly allowed to leave the negotiation after a rejection, in which case they obtain a payoff known value. We show that, when the value of the outside opportunities is of intermediate size, there exist a continuum of subgame-perfect equilibrium outcomes, including some with delayed agreements. Considering outside opportunities of significant value, we prove that efficient delays arise caused by bargainers' aspirations in waiting for their outside option rather than by threats. Moreover, if taking the outside option decreases the probability that the opponent receives an outside option in the future, then it is possible that exactly two equilibrium payoffs coexist. In this latter case, inefficiencies may be created by agreeing too early.Bargaining, outside options

    ADAM15 modulates outside-in signalling in chondrocyte–matrix interactions

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    ADAM15 belongs to a family of transmembrane multi-domain proteins implicated in proteolysis, cell–cell and cell–matrix interactions in various disease conditions. In osteoarthritis (OA), ADAM15 is up-regulated in the chondrocytes already at early stages of cartilage degeneration where it seems to exert homeostatic effects likely associated with its ability to enhance integrin-mediated chondrocyte adhesion to the surrounding collagen matrix. The aim of our present study was, therefore, to characterize functional domains of ADAM15 involved in collagen II (CII) interaction and to analyse associated outside-in signalling events. Accordingly, ADAM15 and respective deletion mutants were stably transfected into the chondrocyte cell line T/C28a4. Transfected cells were adhered to CII and phosphoproteins analysed by Western blotting. Co-immunoprecipitation served to identify protein binding to ADAM15. Our results elucidate the prodomain as critical for the capacity of ADAM15 to enhance CII adhesion, thereby identifying for the first time a cell-adhesive role of a metalloproteinase prodomain. Moreover, the cytoplasmic tail of ADAM15 confers a modulatory effect on the autophosphorylation site Y397 of the focal adhesion kinase (FAK) during chondrocyte–collagen interaction. In conclusion, the newly uncovered impact of ADAM15 on signalling events that arise from chondrocyte interactions with its collagen matrix might contribute to the elucidation of the mechanism underlying its proposed chondroprotective role in degenerative cartilage disease

    GASP XIII. Star formation in gas outside galaxies

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    Based on MUSE data from the GASP survey, we study the Halpha-emitting extraplanar tails of 16 cluster galaxies at z~0.05 undergoing ram pressure stripping. We demonstrate that the dominating ionization mechanism of this gas (between 64% and 94% of the Halpha emission in the tails depending on the diagnostic diagram used) is photoionization by young massive stars due to ongoing star formation (SF) taking place in the stripped tails. This SF occurs in dynamically quite cold HII clumps with a median Halpha velocity dispersion sigma = 27 km s^-1. We study the characteristics of over 500 star-forming clumps in the tails and find median values of Halpha luminosity L_{Halpha} = 4 X 10^38 erg s^-1, dust extinction A_V=0.5 mag, star formation rate SFR=0.003 M_sun yr^-1, ionized gas density n_e =52 cm^-3, ionized gas mass M_gas = 4 X 10^4 Msun, and stellar mass M_{*} = 3 X 10^6 Msun. The tail clumps follow scaling relations (M_gas-M_{*}, L_{Halpha} -sigma, SFR-M_gas) similar to disk clumps, and their stellar masses are comparable to Ultra Compact Dwarfs and Globular Clusters.The diffuse gas component in the tails is ionized by a combination of SF and composite/LINER-like emission likely due to thermal conduction or turbulence. The stellar photoionization component of the diffuse gas can be due either to leakage of ionizing photons from the HII clumps with an average escape fraction of 18%, or lower luminosity HII regions that we cannot individually identify.Comment: accepted for publication in MNRA
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