8,599 research outputs found
Encoding and processing of sensory information in neuronal spike trains
Recently, a statistical signal-processing technique has allowed the information carried by single spike trains of sensory neurons on time-varying stimuli to be characterized quantitatively in a variety of preparations. In weakly electric fish, its application to first-order sensory neurons encoding electric field amplitude (P-receptor afferents) showed that they convey accurate information on temporal modulations in a behaviorally relevant frequency range (<80 Hz). At the next stage of the electrosensory pathway (the electrosensory lateral line lobe, ELL), the information sampled by first-order neurons is used to extract upstrokes and downstrokes in the amplitude modulation waveform. By using signal-detection techniques, we determined that these temporal features are explicitly represented by short spike bursts of second-order neurons (ELL pyramidal cells). Our results suggest that the biophysical mechanism underlying this computation is of dendritic origin. We also investigated the accuracy with which upstrokes and downstrokes are encoded across two of the three somatotopic body maps of the ELL (centromedial and lateral). Pyramidal cells of the centromedial map, in particular I-cells, encode up- and downstrokes more reliably than those of the lateral map. This result correlates well with the significance of these temporal features for a particular behavior (the jamming avoidance response) as assessed by lesion experiments of the centromedial map
Active inference and oculomotor pursuit: the dynamic causal modelling of eye movements.
This paper introduces a new paradigm that allows one to quantify the Bayesian beliefs evidenced by subjects during oculomotor pursuit. Subjects' eye tracking responses to a partially occluded sinusoidal target were recorded non-invasively and averaged. These response averages were then analysed using dynamic causal modelling (DCM). In DCM, observed responses are modelled using biologically plausible generative or forward models - usually biophysical models of neuronal activity
Efficient State-Space Inference of Periodic Latent Force Models
Latent force models (LFM) are principled approaches to incorporating
solutions to differential equations within non-parametric inference methods.
Unfortunately, the development and application of LFMs can be inhibited by
their computational cost, especially when closed-form solutions for the LFM are
unavailable, as is the case in many real world problems where these latent
forces exhibit periodic behaviour. Given this, we develop a new sparse
representation of LFMs which considerably improves their computational
efficiency, as well as broadening their applicability, in a principled way, to
domains with periodic or near periodic latent forces. Our approach uses a
linear basis model to approximate one generative model for each periodic force.
We assume that the latent forces are generated from Gaussian process priors and
develop a linear basis model which fully expresses these priors. We apply our
approach to model the thermal dynamics of domestic buildings and show that it
is effective at predicting day-ahead temperatures within the homes. We also
apply our approach within queueing theory in which quasi-periodic arrival rates
are modelled as latent forces. In both cases, we demonstrate that our approach
can be implemented efficiently using state-space methods which encode the
linear dynamic systems via LFMs. Further, we show that state estimates obtained
using periodic latent force models can reduce the root mean squared error to
17% of that from non-periodic models and 27% of the nearest rival approach
which is the resonator model.Comment: 61 pages, 13 figures, accepted for publication in JMLR. Updates from
earlier version occur throughout article in response to JMLR review
Adaptive Neural Coding Dependent on the Time-Varying Statistics of the Somatic Input Current
It is generally assumed that nerve cells optimize their performance to reflect the statistics of their input. Electronic circuit analogs of neurons require similar methods of self-optimization for stable and autonomous operation. We here describe and demonstrate a biologically plausible adaptive algorithm that enables a neuron to adapt the current threshold and the slope (or gain) of its current-frequency relationship to match the mean (or dc offset) and variance (or dynamic range or contrast) of the time-varying somatic input current. The adaptation algorithm estimates the somatic current signal from the spike train by way of the intracellular somatic calcium concentration, thereby continuously adjusting the neuronś firing dynamics. This principle is shown to work in an analog VLSI-designed silicon neuron
Efficient state-space inference of periodic latent force models
Latent force models (LFM) are principled approaches to incorporating solutions to differen-tial equations within non-parametric inference methods. Unfortunately, the developmentand application of LFMs can be inhibited by their computational cost, especially whenclosed-form solutions for the LFM are unavailable, as is the case in many real world prob-lems where these latent forces exhibit periodic behaviour. Given this, we develop a newsparse representation of LFMs which considerably improves their computational efficiency,as well as broadening their applicability, in a principled way, to domains with periodic ornear periodic latent forces. Our approach uses a linear basis model to approximate onegenerative model for each periodic force. We assume that the latent forces are generatedfrom Gaussian process priors and develop a linear basis model which fully expresses thesepriors. We apply our approach to model the thermal dynamics of domestic buildings andshow that it is effective at predicting day-ahead temperatures within the homes. We alsoapply our approach within queueing theory in which quasi-periodic arrival rates are mod-elled as latent forces. In both cases, we demonstrate that our approach can be implemented efficiently using state-space methods which encode the linear dynamic systems via LFMs.Further, we show that state estimates obtained using periodic latent force models can re-duce the root mean squared error to 17% of that from non-periodic models and 27% of thenearest rival approach which is the resonator model (S ̈arkk ̈a et al., 2012; Hartikainen et al.,2012.
A space communications study Final report, 15 Sep. 1966 - 15 Sep. 1967
Investigation of signal to noise ratios and signal transmission efficiency for space communication system
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