Sometimes the Silence Can Be like the Thunder: Access to Pharmaceutical Data at the FDA

Those committed to the free exchange of scientific information have long complained about various restrictions on access to the FDA\u27s pharmaceutical data and the resultant restrictions on open discourse. A review of open-government procedures and litigation at the FDA demonstrates that the need for transparency at the agency extend well beyond the reach of any clinical trial registry

Sometimes the Silence Can Be like the Thunder: Access to Pharmaceutical Data at the FDA

Those committed to the free exchange of scientific information have long complained about various restrictions on access to the FDA\u27s pharmaceutical data and the resultant restrictions on open discourse. A review of open-government procedures and litigation at the FDA demonstrates that the need for transparency at the agency extend well beyond the reach of any clinical trial registry

Four Statements about the Fourth Generation

This summary of the Workshop "Beyond the 3-generation SM in the LHC era" presents a brief discussion of the following four statements about the fourth generation: 1) It is not excluded by EW precision data; 2) It addresses some of the currently open questions; 3) It can accommodate emerging possible hints of new physics; 4) LHC has the potential to discover or fully exclude it.Comment: Summary of the "Beyond the 3-generation SM in the LHC era" Workshop, CERN, September 4-5, 2008; 7 pages. V2: updated bibliography and minor typos fixed. To appear in PMC Physics

Effective string description of confining flux tubes

We review the current knowledge about the theoretical foundations of the effective string theory for confining flux tubes and the comparison of the predictions to pure gauge lattice data. A concise presentation of the effective string theory is provided, incorporating recent developments. We summarize the predictions for the spectrum and the profile/width of the flux tube and their comparison to lattice data. The review closes with a short summary of open questions for future research.Comment: 21 pages, 8 figures, Contribution to IJMPA special issue "Lattice gauge theory beyond QCD

Improving public services through open data: public toilets

Bichard’s work for the TACT3 project (Bichard REF Output 3) found that UK toilet provision is not centrally collated and no national map or database of toilets exists. In contrast, the UK government’s white paper Open Public Services (2011) emphasised its commitment to incorporating the use of Open Data in public services provision that could be tailored to community preferences, and therefore be more sustainable. Incorporating Open Data on public toilet provision, Bichard and Knight (RCA) developed The Great British Public Toilet Map (GBPTM). Whilst a number of other websites and applications map toilets by ‘crowd surfing’, GBPTM is entirely populated by Open Data, and not only uses the data as information for users, but informs members of the public that such information is available and accessible for their use. This paper presents the development of the GBPTM, including inclusive design research and studies that compare accuracy of information directly provided by users with Open Data collected by local authorities. It suggests that, to meet the health and well-being of an ageing population, a sustainable and cost-effective solution must be found for ‘publicly accessible’ toilet provision, including opening up provision beyond that ‘for customers only’ and providing accurate information on current public provision. The paper highlights the barriers encountered in the production of Open Data by local authorities. A review of the paper in the journal Civil Engineering (May 2013) described the design of the GBPTM as a ‘simple and elegant solution’. The development of a digital output and an understanding of digitally based research led to Bichard’s successful submission to an EPSRC Digital Economy sandpit, in which she developed an interdisciplinary project with the Universities of Newcastle, Bournemouth and the West of England. The project, Family Rituals 2.0, secured £750,000 in research funding with Bichard as co-investigator (2013–15)

Relating parton model and color dipole formulation of heavy quark hadroproduction

At high center of mass energies, hadroproduction of heavy quarks can be expressed in terms of the same color dipole cross section as low Bjorken-x deep inelastic scattering. We show analytically that at leading order, the dipole formulation is equivalent to the gluon-gluon fusion mechanism of the conventional parton model. In phenomenological application, we employ a parameterization of the dipole cross section which also includes higher order and saturation effects, thereby going beyond the parton model. Numerical calculations in the dipole approach agree well with experimental data on open charm production over a wide range of energy. Dipole approach and next to leading order parton model yield similar values for open charm production, but for open bottom production, the dipole approach tends to predict somewhat higher cross sections than the parton model.Comment: 16 pages, 4 figure

Open questions in quarkonium and electromagnetic probes

In my ("not a summary") talk at the Hard Probes 2006 conference, I gave "a personal and surely biased view on only a few of the many open questions on quarkonium and electromagnetic probes". Some of the points reported in that talk are exposed in this paper, having in mind the most important of all the open questions: do we have, today, from experimental data on electromagnetic probes and quarkonium production, convincing evidence that shows, beyond reasonable doubt, the existence of "new physics" in high-energy heavy-ion collisions?Comment: Invited talk at the 2nd Int. Conf. on Hard and EM Probes of High-Energy Nuclear Collisions, Asilomar, California, June 9--16, 2006. To be published in Nuclear Physics A. Late submission to the arXi