200 research outputs found
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Open Access Series of Imaging Studies (OASIS): Cross-sectional MRI Data in Young, Middle Aged, Nondemented, and Demented Older Adults
The Open Access Series of Imaging Studies is a series of magnetic resonance imaging data sets that is publicly available for study and analysis. The initial data set consists of a cross-sectional collection of 416 subjects aged 18 to 96 years. One hundred of the included subjects older than 60 years have been clinically diagnosed with very mild to moderate Alzheimer's disease. The subjects are all right-handed and include both men and women. For each subject, three or four individual T1-weighted magnetic resonance imaging scans obtained in single imaging sessions are included. Multiple within-session acquisitions provide extremely high contrast-to-noise ratio, making the data amenable to a wide range of analytic approaches including automated computational analysis. Additionally, a reliability data set is included containing 20 subjects without dementia imaged on a subsequent visit within 90 days of their initial session. Automated calculation of whole-brain volume and estimated total intracranial volume are presented to demonstrate use of the data for measuring differences associated with normal aging and Alzheimer's disease.Psycholog
Improvement of alzheimer disease diagnosis accuracy using ensemble methods
Nowadays, there is a significant increase in the medical data that we should take advantage of that. The application of the machine learning via the data mining processes, such as data classification depends on using a single classification algorithm or those complained as ensemble models. The objective of this work is to improve the classification accuracy of previous results for Alzheimer disease diagnosing. The Decision Tree algorithm with three types of ensemble methods combined, which are Boosting, Bagging and Stacking. The clinical dataset from the Open Access Series of Imaging Studies (OASIS) was used in the experiments. The experimental results of the proposed approach were better than the previous work results. Where the Random Forest (Bagging) achieved the highest accuracy among all algorithms with 90.69%, while the lowest one was Stacking with 79.07%. All these results generated in this paper are higher in accuracy than that done before
Brain Alzheimer’s disease Detection in Magnetic Resonance Images Using Image Processing
Alzheimer Disease is a chronic neurodegenerative disease and genetic disease that harm the brain nerve cells and tissue loss throughout the brain which causes loss of memory and thinking ability and change in its behavior. In this paper we determine early detection of Alzheimer disease through image processing on Magnetic Resonance Image (MRI) and classification of MRI of brain based on extraction of different features. The paper manifest the application of several image processing technique such as Otsu’s Thresholding and Hidden Markov Random field model (HMRF-EM) and expectation maximization. The feature use for this project acquire from grey Level Co-occurrence Matrix (GLCM) such us Entropy, Homogeneity and Correlation and also the volume ratio of grey matter and white matter to cerebrospinal fluid. This project design in software MATLAB for early detection of Alzheimer disease
3DQ: Compact Quantized Neural Networks for Volumetric Whole Brain Segmentation
Model architectures have been dramatically increasing in size, improving
performance at the cost of resource requirements. In this paper we propose 3DQ,
a ternary quantization method, applied for the first time to 3D Fully
Convolutional Neural Networks (F-CNNs), enabling 16x model compression while
maintaining performance on par with full precision models. We extensively
evaluate 3DQ on two datasets for the challenging task of whole brain
segmentation. Additionally, we showcase our method's ability to generalize on
two common 3D architectures, namely 3D U-Net and V-Net. Outperforming a variety
of baselines, the proposed method is capable of compressing large 3D models to
a few MBytes, alleviating the storage needs in space critical applications.Comment: Accepted to MICCAI 201
Social-sparsity brain decoders: faster spatial sparsity
Spatially-sparse predictors are good models for brain decoding: they give
accurate predictions and their weight maps are interpretable as they focus on a
small number of regions. However, the state of the art, based on total
variation or graph-net, is computationally costly. Here we introduce sparsity
in the local neighborhood of each voxel with social-sparsity, a structured
shrinkage operator. We find that, on brain imaging classification problems,
social-sparsity performs almost as well as total-variation models and better
than graph-net, for a fraction of the computational cost. It also very clearly
outlines predictive regions. We give details of the model and the algorithm.Comment: in Pattern Recognition in NeuroImaging, Jun 2016, Trento, Italy. 201
Fast Predictive Image Registration
We present a method to predict image deformations based on patch-wise image
appearance. Specifically, we design a patch-based deep encoder-decoder network
which learns the pixel/voxel-wise mapping between image appearance and
registration parameters. Our approach can predict general deformation
parameterizations, however, we focus on the large deformation diffeomorphic
metric mapping (LDDMM) registration model. By predicting the LDDMM
momentum-parameterization we retain the desirable theoretical properties of
LDDMM, while reducing computation time by orders of magnitude: combined with
patch pruning, we achieve a 1500x/66x speed up compared to GPU-based
optimization for 2D/3D image registration. Our approach has better prediction
accuracy than predicting deformation or velocity fields and results in
diffeomorphic transformations. Additionally, we create a Bayesian probabilistic
version of our network, which allows evaluation of deformation field
uncertainty through Monte Carlo sampling using dropout at test time. We show
that deformation uncertainty highlights areas of ambiguous deformations. We
test our method on the OASIS brain image dataset in 2D and 3D
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