Evolvable Smartphone-Based Platforms for Point-Of-Care In-Vitro Diagnostics Applications

The association of smart mobile devices and lab-on-chip technologies offers unprecedented opportunities for the emergence of direct-to-consumer in vitro medical diagnostics applications. Despite their clear transformative potential, obstacles remain to the large-scale disruption and long-lasting success of these systems in the consumer market. For instance, the increasing level of complexity of instrumented lab-on-chip devices, coupled to the sporadic nature of point-of-care testing, threatens the viability of a business model mainly relying on disposable/consumable lab-on-chips. We argued recently that system evolvability, defined as the design characteristic that facilitates more manageable transitions between system generations via the modification of an inherited design, can help remedy these limitations. In this paper, we discuss how platform-based design can constitute a formal entry point to the design and implementation of evolvable smart device/lab-on-chip systems. We present both a hardware/software design framework and the implementation details of a platform prototype enabling at this stage the interfacing of several lab-on-chip variants relying on current- or impedance-based biosensors. Our findings suggest that several change-enabling mechanisms implemented in the higher abstraction software layers of the system can promote evolvability, together with the design of change-absorbing hardware/software interfaces. Our platform architecture is based on a mobile software application programming interface coupled to a modular hardware accessory. It allows the specification of lab-on-chip operation and post-analytic functions at the mobile software layer. We demonstrate its potential by operating a simple lab-on-chip to carry out the detection of dopamine using various electroanalytical methods

Design and analysis of LTE and wi-fi schemes for communications of massive machine devices

Existing communication technologies are designed with speciÿc use cases in mind, however, ex-tending these use cases usually throw up interesting challenges. For example, extending the use of existing cellular networks to emerging applications such as Internet of Things (IoT) devices throws up the challenge of handling massive number of devices. In this thesis, we are motivated to investigate existing schemes used in LTE and Wi-Fi for supporting massive machine devices and improve on observed performance gaps by designing new ones that outperform the former. This thesis investigates the existing random access protocol in LTE and proposes three schemes to combat massive device access challenge. The ÿrst is a root index reuse and allocation scheme which uses link budget calculations in extracting a safe distance for preamble reuse under vari-able cell size and also proposes an index allocation algorithm. Secondly, a dynamic subframe optimization scheme that combats the challenge from an optimisation solution perspective. Thirdly, the use of small cells for random access. Simulation and numerical analysis shows performance improvements against existing schemes in terms of throughput, access delay and probability of collision. In some cases, over 20% increase in performance was observed. The proposed schemes provide quicker and more guaranteed opportunities for machine devices to communicate. Also, in Wi-Fi networks, adaptation of the transmission rates to the dynamic channel condi-tions is a major challenge. Two algorithms were proposed to combat this. The ÿrst makes use of contextual information to determine the network state and respond appropriately whilst the second samples candidate transmission modes and uses the e˛ective throughput to make a deci-sion. The proposed algorithms were compared to several existing rate adaptation algorithms by simulations and under various system and channel conÿgurations. They show signiÿcant per-formance improvements, in terms of throughput, thus, conÿrming their suitability for dynamic channel conditions

An agent solution to flexible planning and scheduling of passenger trips

In a highly competitive market, BT1 faces tough challenges as a service provider for telecommunication solutions. A proactive approach to the management of its resources is absolutely mandatory for its success. In this paper, an AI-based planning system for the management of parts of BT’s field force is presented. FieldPlan provides resource managers with full visibility of supply and demand, offers extensive what-if analysis capabilities and thus supports an effective decision making process.IFIP International Conference on Artificial Intelligence in Theory and Practice - Industrial Applications of AIRed de Universidades con Carreras en Informática (RedUNCI

Developing Real-Time Emergency Management Applications: Methodology for a Novel Programming Model Approach

The last years have been characterized by the arising of highly distributed computing platforms composed of a heterogeneity of computing and communication resources including centralized high-performance computing architectures (e.g. clusters or large shared-memory machines), as well as multi-/many-core components also integrated into mobile nodes and network facilities. The emerging of computational paradigms such as Grid and Cloud Computing, provides potential solutions to integrate such platforms with data systems, natural phenomena simulations, knowledge discovery and decision support systems responding to a dynamic demand of remote computing and communication resources and services. In this context time-critical applications, notably emergency management systems, are composed of complex sets of application components specialized for executing specific computations, which are able to cooperate in such a way as to perform a global goal in a distributed manner. Since the last years the scientific community has been involved in facing with the programming issues of distributed systems, aimed at the definition of applications featuring an increasing complexity in the number of distributed components, in the spatial distribution and cooperation between interested parties and in their degree of heterogeneity. Over the last decade the research trend in distributed computing has been focused on a crucial objective. The wide-ranging composition of distributed platforms in terms of different classes of computing nodes and network technologies, the strong diffusion of applications that require real-time elaborations and online compute-intensive processing as in the case of emergency management systems, lead to a pronounced tendency of systems towards properties like self-managing, self-organization, self-controlling and strictly speaking adaptivity. Adaptivity implies the development, deployment, execution and management of applications that, in general, are dynamic in nature. Dynamicity concerns the number and the specific identification of cooperating components, the deployment and composition of the most suitable versions of software components on processing and networking resources and services, i.e., both the quantity and the quality of the application components to achieve the needed Quality of Service (QoS). In time-critical applications the QoS specification can dynamically vary during the execution, according to the user intentions and the Developing Real-Time Emergency Management Applications: Methodology for a Novel Programming Model Approach Gabriele Mencagli and Marco Vanneschi Department of Computer Science, University of Pisa, L. Bruno Pontecorvo, Pisa Italy 2 2 Will-be-set-by-IN-TECH information produced by sensors and services, as well as according to the monitored state and performance of networks and nodes. The general reference point for this kind of systems is the Grid paradigm which, by definition, aims to enable the access, selection and aggregation of a variety of distributed and heterogeneous resources and services. However, though notable advancements have been achieved in recent years, current Grid technology is not yet able to supply the needed software tools with the features of high adaptivity, ubiquity, proactivity, self-organization, scalability and performance, interoperability, as well as fault tolerance and security, of the emerging applications. For this reason in this chapter we will study a methodology for designing high-performance computations able to exploit the heterogeneity and dynamicity of distributed environments by expressing adaptivity and QoS-awareness directly at the application level. An effective approach needs to address issues like QoS predictability of different application configurations as well as the predictability of reconfiguration costs. Moreover adaptation strategies need to be developed assuring properties like the stability degree of a reconfiguration decision and the execution optimality (i.e. select reconfigurations accounting proper trade-offs among different QoS objectives). In this chapter we will present the basic points of a novel approach that lays the foundations for future programming model environments for time-critical applications such as emergency management systems. The organization of this chapter is the following. In Section 2 we will compare the existing research works for developing adaptive systems in critical environments, highlighting their drawbacks and inefficiencies. In Section 3, in order to clarify the application scenarios that we are considering, we will present an emergency management system in which the run-time selection of proper application configuration parameters is of great importance for meeting the desired QoS constraints. In Section 4we will describe the basic points of our approach in terms of how compute-intensive operations can be programmed, how they can be dynamically modified and how adaptation strategies can be expressed. In Section 5 our approach will be contextualize to the definition of an adaptive parallel module, which is a building block for composing complex and distributed adaptive computations. Finally in Section 6 we will describe a set of experimental results that show the viability of our approach and in Section 7 we will give the concluding remarks of this chapter

Compressing and forecasting atomic material simulations with descriptors

Atomic simulations of material microstructure require significant resources to generate, store and analyze. Here, atomic descriptor functions are proposed as a general latent space to compress atomic microstructure, ideal for use in large-scale simulations. Descriptors can regress a broad range of properties, including character-dependent dislocation densities, stress states or radial distribution functions. A vector autoregressive model can generate trajectories over yield points, resample from new initial conditions and forecast trajectory futures. A forecast confidence, essential for practical application, is derived by propagating forecasts through the Mahalanobis outlier distance, providing a powerful tool to assess coarse-grained models. Application to nanoparticles and yielding of dislocation networks confirms low uncertainty forecasts are accurate and resampling allows for the propagation of smooth microstructure distributions. Yielding is associated with a collapse in the intrinsic dimension of the descriptor manifold, which is discussed in relation to the yield surface.Comment: 13 pages, 13 figure

Integrated agent-based microsimulation framework for examining impacts of mobility-oriented policies

open6siTravel demand management measures/policies are important to sustain positive changes among individuals’ travel behaviour. An integrated agent-based microsimulation platform provides a rich framework for examining such interventions to assess their impacts using indicators about demand as well as supply side. This paper presents an approach where individual schedules, derived from a lighter version of an activity-based model, are fed into a Multi-Agent Transport Simulation (MATSIM) framework. Simulations are performed for two European cities i.e. Hasselt (Belgium) and Bologna (Italy). After calibrating the modelling framework against aggregate traffic counts for the base case, the impacts of a few traffic management policies (restricting car access, increase in bus frequency) are examined. The results indicate that restricting car access is more effective in terms of reducing traffic from the network and also shifting car drivers/passengers to other modes of travel. The enhancement of bus infrastructure in relation to increase in frequency caused shifting of bicyclist towards public transport, which is an undesirable result of the policy if the objective is to improve sustainability and environment. In future research, the framework will be enhanced to integrate emission and air dispersion models to ascertain effects on air quality as a result of such interventions.embargoed_20210117Adnan, Muhammad; Outay, Fatma; Ahmed, Shiraz; Brattich, Erika; di Sabatino, Silvana; Janssens, DavyAdnan, Muhammad; Outay, Fatma; Ahmed, Shiraz; Brattich, Erika; di Sabatino, Silvana; Janssens, Dav

Enable Reliable and Secure Data Transmission in Resource-Constrained Emerging Networks

The increasing deployment of wireless devices has connected humans and objects all around the world, benefiting our daily life and the entire society in many aspects. Achieving those connectivity motivates the emergence of different types of paradigms, such as cellular networks, large-scale Internet of Things (IoT), cognitive networks, etc. Among these networks, enabling reliable and secure data transmission requires various resources including spectrum, energy, and computational capability. However, these resources are usually limited in many scenarios, especially when the number of devices is considerably large, bringing catastrophic consequences to data transmission. For example, given the fact that most of IoT devices have limited computational abilities and inadequate security protocols, data transmission is vulnerable to various attacks such as eavesdropping and replay attacks, for which traditional security approaches are unable to address. On the other hand, in the cellular network, the ever-increasing data traffic has exacerbated the depletion of spectrum along with the energy consumption. As a result, mobile users experience significant congestion and delays when they request data from the cellular service provider, especially in many crowded areas. In this dissertation, we target on reliable and secure data transmission in resource-constrained emerging networks. The first two works investigate new security challenges in the current heterogeneous IoT environment, and then provide certain countermeasures for reliable data communication. To be specific, we identify a new physical-layer attack, the signal emulation attack, in the heterogeneous environment, such as smart home IoT. To defend against the attack, we propose two defense strategies with the help of a commonly found wireless device. In addition, to enable secure data transmission in large-scale IoT network, e.g., the industrial IoT, we apply the amply-and-forward cooperative communication to increase the secrecy capacity by incentivizing relay IoT devices. Besides security concerns in IoT network, we seek data traffic alleviation approaches to achieve reliable and energy-efficient data transmission for a group of users in the cellular network. The concept of mobile participation is introduced to assist data offloading from the base station to users in the group by leveraging the mobility of users and the social features among a group of users. Following with that, we deploy device-to-device data offloading within the group to achieve the energy efficiency at the user side while adapting to their increasing traffic demands. In the end, we consider a perpendicular topic - dynamic spectrum access (DSA) - to alleviate the spectrum scarcity issue in cognitive radio network, where the spectrum resource is limited to users. Specifically, we focus on the security concerns and further propose two physical-layer schemes to prevent spectrum misuse in DSA in both additive white Gaussian noise and fading environments

Signal Processing in Wireless Communications: Device Fingerprinting and Wide-Band Interference Rejection

The rapid progress of wireless communication technologies that has taken place in recent years has significantly improved the quality of everyday life. However with this expansion of wireless communication systems come significant security threats and significant technological challenges, both of which are due to the fact that the communication medium is shared. The ubiquity of open wireless Internet access networks creates a new avenue for cyber-criminals to impersonate and act in an unauthorized way. The increasing number of deployed wide-band wireless communication systems entails technological challenges for effective utilization of the shared medium, which implies the need for advanced interference rejection methods. Wireless security and interference rejection in wide-band wireless communications are therefore often considered as the two main challenges in wireless network\u27s design and research. Important aspects of these challenges are illuminated and addressed in this dissertation. This dissertation considers signal processing approaches for exploiting or mitigating the effects of non-ideal components in wireless communication systems. In the first part of the dissertation, we introduce and study a novel, model-based approach to wireless device identification that exploits imperfections in the transmitter caused by manufacturing process nonidealities. Previous approaches to device identification based on hardware imperfections vary from transient analysis to machine learning but have not provided verifiable accuracy. Here, we detail a model-based approach, that uses statistical models of RF transmitter components: digital-to-analog converter, power amplifier and RF oscillator, which are amenable for analysis. Our proposed approach examines the key device characteristics that cause anonymity loss, countermeasures that can be applied by the nodes to regain the anonymity, and ways of thwarting such countermeasures. We develop identification algorithms based on statistical signal processing methods and address the challenging scenario when the units that need to be distinguished from one another are of the same model and from the same manufacturer. Using simulations and measurements of components that are commonly used in commercial communications systems, we show that our anonymity breaking techniques are effective. In the second part of the dissertation, we consider innovative approaches for the acquisition of frequency-sparse signals with wide-band receivers when a weak signal of interest is received in the presence of a very strong interference, and the effects of the nonlinearities in the low-noise amplifier at the receiver must be mitigated. All samples with amplitude above a given threshold, dictated by the linear input range of the receiver, are discarded to avoid the distortion caused by saturation of the low noise amplifier. Such a sampling scheme, while avoiding nonlinear distortion that cannot be corrected in the digital domain, poses challenges for signal reconstruction techniques, as the samples are taken non-uniformly, but also non-randomly. The considered approaches fall into the field of compressive sensing (CS); however, what differentiates them from conventional CS is that a structure is forced upon the measurement scheme. Such a structure causes a violation of the core CS assumption of the measurements\u27 randomness. We consider two different types of structured acquisition: signal independent and signal dependent structured acquisition. For the first case, we derive bounds on the number of samples needed for successful CS recovery when samples are drawn at random in predefined groups. For the second case, we consider enhancements of CS recovery methods when only small-amplitude samples of the signal that needs to be recovered are available for the recovery. Finally, we address a problem of spectral leakage due to the limited processing block size of block processing, wide-band receivers and propose an adaptive block size adjustment method, which leads to significant dynamic range improvements