A quantitative study of the orientation bias of some edge detector schemes

The evaluation of a particular set of edge detection schemes is described. The results obtained are compared with those obtained from an edge detection scheme using a texture oriented approach. The orientational bias of these schemes is emphasized. Improved qualitative observations are reported and a comparison of the evaluation method with another edge detection evaluation method is presented

Accurate detection of dysmorphic nuclei using dynamic programming and supervised classification

A vast array of pathologies is typified by the presence of nuclei with an abnormal morphology. Dysmorphic nuclear phenotypes feature dramatic size changes or foldings, but also entail much subtler deviations such as nuclear protrusions called blebs. Due to their unpredictable size, shape and intensity, dysmorphic nuclei are often not accurately detected in standard image analysis routines. To enable accurate detection of dysmorphic nuclei in confocal and widefield fluorescence microscopy images, we have developed an automated segmentation algorithm, called Blebbed Nuclei Detector (BleND), which relies on two-pass thresholding for initial nuclear contour detection, and an optimal path finding algorithm, based on dynamic programming, for refining these contours. Using a robust error metric, we show that our method matches manual segmentation in terms of precision and outperforms state-of-the-art nuclear segmentation methods. Its high performance allowed for building and integrating a robust classifier that recognizes dysmorphic nuclei with an accuracy above 95%. The combined segmentation-classification routine is bound to facilitate nucleus-based diagnostics and enable real-time recognition of dysmorphic nuclei in intelligent microscopy workflows

Unsupervised Learning of Edges

Data-driven approaches for edge detection have proven effective and achieve top results on modern benchmarks. However, all current data-driven edge detectors require manual supervision for training in the form of hand-labeled region segments or object boundaries. Specifically, human annotators mark semantically meaningful edges which are subsequently used for training. Is this form of strong, high-level supervision actually necessary to learn to accurately detect edges? In this work we present a simple yet effective approach for training edge detectors without human supervision. To this end we utilize motion, and more specifically, the only input to our method is noisy semi-dense matches between frames. We begin with only a rudimentary knowledge of edges (in the form of image gradients), and alternate between improving motion estimation and edge detection in turn. Using a large corpus of video data, we show that edge detectors trained using our unsupervised scheme approach the performance of the same methods trained with full supervision (within 3-5%). Finally, we show that when using a deep network for the edge detector, our approach provides a novel pre-training scheme for object detection.Comment: Camera ready version for CVPR 201