Proto–neural networks from thermal proteins

Proteinoids are synthetic polymers that have structural similarities to natural proteins, and their formation is achieved through the application of heat to amino acid combinations in a dehydrated environment. The thermal proteins, initially synthesised by Sidney Fox during the 1960s, has the ability to undergo self-assembly, resulting in the formation of microspheres that resemble cells. These microspheres have fascinating biomimetic characteristics. In recent studies, substantial advancements have been made in elucidating the electrical signalling phenomena shown by proteinoids, hence showcasing their promising prospects in the field of neuro-inspired computing. This study demonstrates the advancement of experimental prototypes that employ proteinoids in the construction of fundamental neural network structures. The article provides an overview of significant achievements in proteinoid systems, such as the demonstration of electrical excitability, emulation of synaptic functions, capabilities in pattern recognition, and adaptability of network structures. This study examines the similarities and differences between proteinoid networks and spontaneous neural computation. We examine the persistent challenges associated with deciphering the underlying mechanisms of emergent proteinoid-based intelligence. Additionally, we explore the potential for developing bio-inspired computing systems using synthetic thermal proteins in forthcoming times. The results of this study offer a theoretical foundation for the advancement of adaptive, self-assembling electronic systems that operate using artificial bio-neural principles. [Abstract copyright: Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.

Challenges and solutions for large-scale integration of emerging technologies

Title from PDF of title page viewed June 15, 2021Dissertation advisor: Mostafizur RahmanVitaIncludes bibliographical references (pages 67-88)Thesis (Ph.D.)--School of Computing and Engineering and Department of Physics and Astronomy. University of Missouri--Kansas City, 2021The semiconductor revolution so far has been primarily driven by the ability to shrink devices and interconnects proportionally (Moore's law) while achieving incremental benefits. In sub-10nm nodes, device scaling reaches its fundamental limits, and the interconnect bottleneck is dominating power and performance. As the traditional way of CMOS scaling comes to an end, it is essential to find an alternative to continue this progress. However, an alternative technology for general-purpose computing remains elusive; currently pursued research directions face adoption challenges in all aspects from materials, devices to architecture, thermal management, integration, and manufacturing. Crosstalk Computing, a novel emerging computing technique, addresses some of the challenges and proposes a new paradigm for circuit design, scaling, and security. However, like other emerging technologies, Crosstalk Computing also faces challenges like designing large-scale circuits using existing CAD tools, scalability, evaluation and benchmarking of large-scale designs, experimentation through commercial foundry processes to compete/co-exist with CMOS for digital logic implementations. This dissertation addresses these issues by providing a methodology for circuit synthesis customizing the existing EDA tool flow, evaluating and benchmarking against state-of-the-art CMOS for large-scale circuits designed at 7nm from MCNC benchmark suits. This research also presents a study on Crosstalk technology's scalability aspects and shows how the circuits' properties evolve from 180nm to 7nm technology nodes. Some significant results are for primitive Crosstalk gate, designed in 180nm, 65nm, 32nm, and 7nm technology nodes, the average reduction in power is 42.5%, and an average improvement in performance is 34.5% comparing to CMOS for all mentioned nodes. For benchmarking large-scale circuits designed at 7nm, there are 48%, 57%, and 10% improvements against CMOS designs in terms of density, power, and performance, respectively. An experimental demonstration of a proof-of-concept prototype chip for Crosstalk Computing at TSMC 65nm technology is also presented in this dissertation, showing the Crosstalk gates can be realized using the existing manufacturing process. Additionally, the dissertation also provides a fine-grained thermal management approach for emerging technologies like transistor-level 3-D integration (Monolithic 3-D, Skybridge, SN3D), which holds the most promise beyond 2-D CMOS technology. However, such 3-D architectures within small form factors increase hotspots and demand careful consideration of thermal management at all integration levels. This research proposes a new direction for fine-grained thermal management approach for transistor-level 3-D integrated circuits through the insertion of architected heat extraction features that can be part of circuit design, and an integrated methodology for thermal evaluation of 3-D circuits combining different simulation outcomes at advanced nodes, which can be integrated to traditional CAD flow. The results show that the proposed heat extraction features effectively reduce the temperature from a heated location. Thus, the dissertation provides a new perspective to overcome the challenges faced by emerging technologies where the device, circuit, connectivity, heat management, and manufacturing are addressed in an integrated manner.Introduction and motivation -- Cross talk computing overview -- Logic simplification approach for Crosstalk circuit design -- Crostalk computing scalability study: from 180 nm to 7 nm -- Designing large*scale circuits in Crosstalk at 7 nm -- Comparison and benchmarking -- Experimental demonstration of Crosstalk computing -- Thermal management challenges and mitigation techniques for transistor-level- 3D integratio

Crosstalk computing: circuit techniques, implementation and potential applications

Title from PDF of title [age viewed January 32, 2022Dissertation advisor: Mostafizur RahmanVitaIncludes bibliographical references (page 117-136)Thesis (Ph.D.)--School of Computing and Engineering. University of Missouri--Kansas City, 2020This work presents a radically new computing concept for digital Integrated Circuits (ICs), called Crosstalk Computing. The conventional CMOS scaling trend is facing device scaling limitations and interconnect bottleneck. The other primary concern of miniaturization of ICs is the signal-integrity issue due to Crosstalk, which is the unwanted interference of signals between neighboring metal lines. The Crosstalk is becoming inexorable with advancing technology nodes. Traditional computing circuits always tries to reduce this Crosstalk by applying various circuit and layout techniques. In contrast, this research develops novel circuit techniques that can leverage this detrimental effect and convert it astutely to a useful feature. The Crosstalk is engineered into a logic computation principle by leveraging deterministic signal interference for innovative circuit implementation. This research work presents a comprehensive circuit framework for Crosstalk Computing and derives all the key circuit elements that can enable this computing model. Along with regular digital logic circuits, it also presents a novel Polymorphic circuit approach unique to Crosstalk Computing. In Polymorphic circuits, the functionality of a circuit can be altered using a control variable. Owing to the multi-functional embodiment in polymorphic-circuits, they find many useful applications such as reconfigurable system design, resource sharing, hardware security, and fault-tolerant circuit design, etc. This dissertation shows a comprehensive list of polymorphic logic gate implementations, which were not reported previously in any other work. It also performs a comparison study between Crosstalk polymorphic circuits and existing polymorphic approaches, which are either inefficient due to custom non-linear circuit styles or propose exotic devices. The ability to design a wide range of polymorphic logic circuits (basic and complex logics) compact in design and minimal in transistor count is unique to Crosstalk Computing, which leads to benefits in the circuit density, power, and performance. The circuit simulation and characterization results show a 6x improvement in transistor count, 2x improvement in switching energy, and 1.5x improvement in performance compared to counterpart implementation in CMOS circuit style. Nevertheless, the Crosstalk circuits also face issues while cascading the circuits; this research analyzes all the problems and develops auxiliary circuit techniques to fix the problems. Moreover, it shows a module-level cascaded polymorphic circuit example, which also employs the auxiliary circuit techniques developed. For the very first time, it implements a proof-of-concept prototype Chip for Crosstalk Computing at TSMC 65nm technology and demonstrates experimental evidence for runtime reconfiguration of the polymorphic circuit. The dissertation also explores the application potentials for Crosstalk Computing circuits. Finally, the future work section discusses the Electronic Design Automation (EDA) challenges and proposes an appropriate design flow; besides, it also discusses ideas for the efficient implementation of Crosstalk Computing structures. Thus, further research and development to realize efficient Crosstalk Computing structures can leverage the comprehensive circuit framework developed in this research and offer transformative benefits for the semiconductor industry.Introduction and Motivation -- More Moore and Relevant Beyond CMOS Research Directions -- Crosstalk Computing -- Crosstalk Circuits Based on Perception Model -- Crosstalk Circuit Types -- Cascading Circuit Issues and Sollutions -- Existing Polymorphic Circuit Approaches -- Crosstalk Polymorphic Circuits -- Comparison and Benchmarking of Crosstalk Gates -- Practical Realization of Crosstalk Gates -- Poential Applications -- Conclusion and Future Wor