Active inference, eye movements and oculomotor delays.

This paper considers the problem of sensorimotor delays in the optimal control of (smooth) eye movements under uncertainty. Specifically, we consider delays in the visuo-oculomotor loop and their implications for active inference. Active inference uses a generalisation of Kalman filtering to provide Bayes optimal estimates of hidden states and action in generalised coordinates of motion. Representing hidden states in generalised coordinates provides a simple way of compensating for both sensory and oculomotor delays. The efficacy of this scheme is illustrated using neuronal simulations of pursuit initiation responses, with and without compensation. We then consider an extension of the generative model to simulate smooth pursuit eye movements-in which the visuo-oculomotor system believes both the target and its centre of gaze are attracted to a (hidden) point moving in the visual field. Finally, the generative model is equipped with a hierarchical structure, so that it can recognise and remember unseen (occluded) trajectories and emit anticipatory responses. These simulations speak to a straightforward and neurobiologically plausible solution to the generic problem of integrating information from different sources with different temporal delays and the particular difficulties encountered when a system-like the oculomotor system-tries to control its environment with delayed signals

Six networks on a universal neuromorphic computing substrate

In this study, we present a highly configurable neuromorphic computing substrate and use it for emulating several types of neural networks. At the heart of this system lies a mixed-signal chip, with analog implementations of neurons and synapses and digital transmission of action potentials. Major advantages of this emulation device, which has been explicitly designed as a universal neural network emulator, are its inherent parallelism and high acceleration factor compared to conventional computers. Its configurability allows the realization of almost arbitrary network topologies and the use of widely varied neuronal and synaptic parameters. Fixed-pattern noise inherent to analog circuitry is reduced by calibration routines. An integrated development environment allows neuroscientists to operate the device without any prior knowledge of neuromorphic circuit design. As a showcase for the capabilities of the system, we describe the successful emulation of six different neural networks which cover a broad spectrum of both structure and functionality

The stochastic neural network in VLSI for studying noise communication in crayfish

L'attivita neurale in natura presenta un andamento stocastico e gioca un ruolo significativo nel cervello. Tuttavia, la maggior parte degli articoli si limitano alla simulazione di neuroni stocastici. In questa tesi, proponiamo un nuovo modello stocastico secondo il formalismo di Hodgkin-Huxley basato su equazioni dierenziali stocastiche e moto browniano. Il nuovo modello di equazione dierenziale stocastiche riproduce una vasta gamma di dinamiche in modo piu realistico rispetto ai precedenti modelli deterministici. Tale modello stocastico e stato applicata a una semplice rete neurale che si trova sulla coda di un gambero chiamato CPR (caudal photoreceptor). Presentiamo una libreria di operatori analogici stocastici utilizzati per il calcolo analogico in tempo reale. Questa libreria permette di ottenere una implementazione in silicio della rete stocastica CPR che sarà collegata alle cellule nervose del gambero. L'interazione vivente-articiali permettera ai biologisti di comprendere meglio i fenomeni nervosi // The Neural activity in nature presents a stochastic trend and plays an important role in the brain. However, most papers are limited simulating stochastic neurons. In this thesis, we propose a novel stochastic model according to the Hodgkin{Huxley formalism using stochastic dierential equations and Brownian motion. The new stochastic dierential equation model reproduces a large range of dynamics more realistically than previous deterministic models. Such stochastic model has been applied to simple neural network that is located on the tail of the craysh called CPR (caudal photoreceptor). We present a library of stochastic analog operators used for the analog real-time computation. This library allows to obtain a silicon implementation of the CPR stochastic network that will be connected to the nerve cells of the craysh. The living-articial interaction will allow biologists to better understand the nervous phenomen