35 research outputs found

    Rotation-Covariant Texture Learning Using Steerable Riesz Wavelets

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    We propose a texture learning approach that exploits local organizations of scales and directions. First, linear combinations of Riesz wavelets are learned using kernel support vector machines. The resulting texture signatures are modeling optimal class-wise discriminatory properties. The visualization of the obtained signatures allows verifying the visual relevance of the learned concepts. Second, the local orientations of the signatures are optimized to maximize their responses, which is carried out analytically and can still be expressed as a linear combination of the initial steerable Riesz templates. The global process is iteratively repeated to obtain final rotation-covariant texture signatures. Rapid convergence of class-wise signatures is observed, which demonstrates that the instances are projected into a feature space that leverages the local organizations of scales and directions. Experimental evaluation reveals average classification accuracies in the range of 97% to 98% for the Outex_TC_00010, the Outex_TC_00012, and the Contrib_TC_00000 suites for even orders of the Riesz transform, and suggests high robustness to changes in images orientation and illumination. The proposed framework requires no arbitrary choices of scales and directions and is expected to perform well in a large range of computer vision applications

    Texture Analysis Platform for Imaging Biomarker Research

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    abstract: The rate of progress in improving survival of patients with solid tumors is slow due to late stage diagnosis and poor tumor characterization processes that fail to effectively reflect the nature of tumor before treatment or the subsequent change in its dynamics because of treatment. Further advancement of targeted therapies relies on advancements in biomarker research. In the context of solid tumors, bio-specimen samples such as biopsies serve as the main source of biomarkers used in the treatment and monitoring of cancer, even though biopsy samples are susceptible to sampling error and more importantly, are local and offer a narrow temporal scope. Because of its established role in cancer care and its non-invasive nature imaging offers the potential to complement the findings of cancer biology. Over the past decade, a compelling body of literature has emerged suggesting a more pivotal role for imaging in the diagnosis, prognosis, and monitoring of diseases. These advances have facilitated the rise of an emerging practice known as Radiomics: the extraction and analysis of large numbers of quantitative features from medical images to improve disease characterization and prediction of outcome. It has been suggested that radiomics can contribute to biomarker discovery by detecting imaging traits that are complementary or interchangeable with other markers. This thesis seeks further advancement of imaging biomarker discovery. This research unfolds over two aims: I) developing a comprehensive methodological pipeline for converting diagnostic imaging data into mineable sources of information, and II) investigating the utility of imaging data in clinical diagnostic applications. Four validation studies were conducted using the radiomics pipeline developed in aim I. These studies had the following goals: (1 distinguishing between benign and malignant head and neck lesions (2) differentiating benign and malignant breast cancers, (3) predicting the status of Human Papillomavirus in head and neck cancers, and (4) predicting neuropsychological performances as they relate to Alzheimer’s disease progression. The long-term objective of this thesis is to improve patient outcome and survival by facilitating incorporation of routine care imaging data into decision making processes.Dissertation/ThesisDoctoral Dissertation Biomedical Informatics 201

    Retrieval of high-dimensional visual data: current state, trends and challenges ahead

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    Information retrieval algorithms have changed the way we manage and use various data sources, such as images, music or multimedia collections. First, free text information of documents from varying sources became accessible in addition to structured data in databases, initially for exact search and then for more probabilistic models. Novel approaches enable content-based visual search of images using computerized image analysis making visual image content searchable without requiring high quality manual annotations. Other multimedia data followed such as video and music retrieval, sometimes based on techniques such as extracting objects and classifying genre. 3D (surface) objects and solid textures have also been produced in quickly increasing quantities, for example in medical tomographic imaging. For these two types of 3D information sources, systems have become available to characterize the objects or textures and search for similar visual content in large databases. With 3D moving sequences (i.e., 4D), in particular medical imaging, even higher-dimensional data have become available for analysis and retrieval and currently present many multimedia retrieval challenges. This article systematically reviews current techniques in various fields of 3D and 4D visual information retrieval and analyses the currently dominating application areas. The employed techniques are analysed and regrouped to highlight similarities and complementarities among them in order to guide the choice of optimal approaches for new 3D and 4D retrieval problems. Opportunities for future applications conclude the article. 3D or higher-dimensional visual information retrieval is expected to grow quickly in the coming years and in this respect this article can serve as a basis for designing new applications

    Computational imaging and automated identification for aqueous environments

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    Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution June 2011Sampling the vast volumes of the ocean requires tools capable of observing from a distance while retaining detail necessary for biology and ecology, ideal for optical methods. Algorithms that work with existing SeaBED AUV imagery are developed, including habitat classi fication with bag-of-words models and multi-stage boosting for rock sh detection. Methods for extracting images of sh from videos of longline operations are demonstrated. A prototype digital holographic imaging device is designed and tested for quantitative in situ microscale imaging. Theory to support the device is developed, including particle noise and the effects of motion. A Wigner-domain model provides optimal settings and optical limits for spherical and planar holographic references. Algorithms to extract the information from real-world digital holograms are created. Focus metrics are discussed, including a novel focus detector using local Zernike moments. Two methods for estimating lateral positions of objects in holograms without reconstruction are presented by extending a summation kernel to spherical references and using a local frequency signature from a Riesz transform. A new metric for quickly estimating object depths without reconstruction is proposed and tested. An example application, quantifying oil droplet size distributions in an underwater plume, demonstrates the efficacy of the prototype and algorithms.Funding was provided by NOAA Grant #5710002014, NOAA NMFS Grant #NA17RJ1223, NSF Grant #OCE-0925284, and NOAA Grant #NA10OAR417008

    Overcomplete Image Representations for Texture Analysis

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    Advisor/s: Dr. Boris Escalante-Ramírez and Dr. Gabriel Cristóbal. Date and location of PhD thesis defense: 23th October 2013, Universidad Nacional Autónoma de México.In recent years, computer vision has played an important role in many scientific and technological areas mainlybecause modern society highlights vision over other senses. At the same time, application requirements and complexity have also increased so that in many cases the optimal solution depends on the intrinsic charac-teristics of the problem; therefore, it is difficult to propose a universal image model. In parallel, advances in understanding the human visual system have allowed to propose sophisticated models that incorporate simple phenomena which occur in early stages of the visual system. This dissertation aims to investigate characteristicsof vision such as over-representation and orientation of receptive fields in order to propose bio-inspired image models for texture analysis

    Shifting representations:Adventures in cross-modality domain adaptation for medical image analysis

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    Shifting representations:Adventures in cross-modality domain adaptation for medical image analysis

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    Computational imaging and automated identification for aqueous environments

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    Thesis (Ph. D.)--Joint Program in Oceanography/Applied Ocean Science and Engineering (Massachusetts Institute of Technology, Dept. of Mechanical Engineering; and the Woods Hole Oceanographic Institution), 2011."June 2011." Cataloged from PDF version of thesis.Includes bibliographical references (p. 253-293).Sampling the vast volumes of the ocean requires tools capable of observing from a distance while retaining detail necessary for biology and ecology, ideal for optical methods. Algorithms that work with existing SeaBED AUV imagery are developed, including habitat classification with bag-of-words models and multi-stage boosting for rock sh detection. Methods for extracting images of sh from videos of long-line operations are demonstrated. A prototype digital holographic imaging device is designed and tested for quantitative in situ microscale imaging. Theory to support the device is developed, including particle noise and the effects of motion. A Wigner-domain model provides optimal settings and optical limits for spherical and planar holographic references. Algorithms to extract the information from real-world digital holograms are created. Focus metrics are discussed, including a novel focus detector using local Zernike moments. Two methods for estimating lateral positions of objects in holograms without reconstruction are presented by extending a summation kernel to spherical references and using a local frequency signature from a Riesz transform. A new metric for quickly estimating object depths without reconstruction is proposed and tested. An example application, quantifying oil droplet size distributions in an underwater plume, demonstrates the efficacy of the prototype and algorithms.by Nicholas C. Loomis.Ph.D
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