Hierarchical workflow management system for life science applications

In modern laboratories, an increasing number of automated stations and instruments are applied as standalone automated systems such as biological high throughput screening systems, chemical parallel reactors etc. At the same time, the mobile robot transportation solution becomes popular with the development of robotic technologies. In this dissertation, a new superordinate control system, called hierarchical workflow management system (HWMS) is presented to manage and to handle both, automated laboratory systems and logistics systems.In modernen Labors werden immer mehr automatisierte Stationen und Instrumente als eigenständige automatisierte Systeme eingesetzt, wie beispielsweise biologische High-Throughput-Screening-Systeme und chemische Parallelreaktoren. Mit der Entwicklung der Robotertechnologien wird gleichzeitig die mobile Robotertransportlösung populär. In der vorliegenden Arbeit wurde ein hierarchisches Verwaltungssystem für Abeitsablauf, welches auch als HWMS bekannt ist, entwickelt. Das neue übergeordnete Kontrollsystem kann sowohl automatisierte Laborsysteme als auch Logistiksysteme verwalten und behandeln

An intelligent multi-floor mobile robot transportation system in life science laboratories

In this dissertation, a new intelligent multi-floor transportation system based on mobile robot is presented to connect the distributed laboratories in multi-floor environment. In the system, new indoor mapping and localization are presented, hybrid path planning is proposed, and an automated doors management system is presented. In addition, a hybrid strategy with innovative floor estimation to handle the elevator operations is implemented. Finally the presented system controls the working processes of the related sub-system. The experiments prove the efficiency of the presented system

Mobile robot transportation in laboratory automation

In this dissertation a new mobile robot transportation system is developed for the modern laboratory automation to connect the distributed automated systems and workbenches. In the system, a series of scientific and technical robot indoor issues are presented and solved, including the multiple robot control strategy, the indoor transportation path planning, the hybrid robot indoor localization, the recharging optimization, the robot-automated door interface, the robot blind arm grasping & placing, etc. The experiments show the proposed system and methods are effective and efficient

Intelligent strategies for mobile robotics in laboratory automation

In this thesis a new intelligent framework is presented for the mobile robots in laboratory automation, which includes: a new multi-floor indoor navigation method is presented and an intelligent multi-floor path planning is proposed; a new signal filtering method is presented for the robots to forecast their indoor coordinates; a new human feature based strategy is proposed for the robot-human smart collision avoidance; a new robot power forecasting method is proposed to decide a distributed transportation task; a new blind approach is presented for the arm manipulations for the robots

Ground Robotic Hand Applications for the Space Program study (GRASP)

This document reports on a NASA-STDP effort to address research interests of the NASA Kennedy Space Center (KSC) through a study entitled, Ground Robotic-Hand Applications for the Space Program (GRASP). The primary objective of the GRASP study was to identify beneficial applications of specialized end-effectors and robotic hand devices for automating any ground operations which are performed at the Kennedy Space Center. Thus, operations for expendable vehicles, the Space Shuttle and its components, and all payloads were included in the study. Typical benefits of automating operations, or augmenting human operators performing physical tasks, include: reduced costs; enhanced safety and reliability; and reduced processing turnaround time

Robotics and automation in the city: a research agenda

Globally cities are becoming experimental sites for new forms of robotic and automation technologies applied across a wide variety of sectors in multiple areas of economic and social life. As these innovations leave the laboratory and factory, this paper analyses how robotics and automation systems are being layered upon existing urban digital networks, extending the capabilities and capacities of human agency and infrastructure networks, and reshaping the city and citizen’s everyday experiences. To date, most work in this field has been speculative and isolated in nature. We set out a research agenda that goes beyond analysis of discrete applications and effects, to investigate how robotics and automation connect across urban domains and the implications for: differential urban geographies, the selective enhancement of individuals and collective management of infrastructures, the socio-spatial sorting of cities and the potential for responsible urban innovation

Towards Robotic Laboratory Automation Plug & Play: The "LAPP" Framework

Increasing the level of automation in pharmaceutical laboratories and production facilities plays a crucial role in delivering medicine to patients. However, the particular requirements of this field make it challenging to adapt cutting-edge technologies present in other industries. This article provides an overview of relevant approaches and how they can be utilized in the pharmaceutical industry, especially in development laboratories. Recent advancements include the application of flexible mobile manipulators capable of handling complex tasks. However, integrating devices from many different vendors into an end-to-end automation system is complicated due to the diversity of interfaces. Therefore, various approaches for standardization are considered in this article, and a concept is proposed for taking them a step further. This concept enables a mobile manipulator with a vision system to "learn" the pose of each device and - utilizing a barcode - fetch interface information from a universal cloud database. This information includes control and communication protocol definitions and a representation of robot actions needed to operate the device. In order to define the movements in relation to the device, devices have to feature - besides the barcode - a fiducial marker as standard. The concept will be elaborated following appropriate research activities in follow-up papers

Process automation for analytical measurements providing high precise sample preparation in life science applications

Laboratories providing life science applications will gain on improved analysis´ efficiency and reliability by automating sample pretreatment. However, commercially available automated systems are especially suitable for the standardized MTP-format allowing for biological assays, whereas automating analytical sample pretreatment is still an unsolved challenge. Therefore, the purpose of this presentation is the design, the realization, and evaluation of an automated system that supplies multistep analytical sample pretreatment and high flexibility for easy upgrading and performance adaption