Biosignal‐based human–machine interfaces for assistance and rehabilitation : a survey

As a definition, Human–Machine Interface (HMI) enables a person to interact with a device. Starting from elementary equipment, the recent development of novel techniques and unobtrusive devices for biosignals monitoring paved the way for a new class of HMIs, which take such biosignals as inputs to control various applications. The current survey aims to review the large literature of the last two decades regarding biosignal‐based HMIs for assistance and rehabilitation to outline state‐of‐the‐art and identify emerging technologies and potential future research trends. PubMed and other databases were surveyed by using specific keywords. The found studies were further screened in three levels (title, abstract, full‐text), and eventually, 144 journal papers and 37 conference papers were included. Four macrocategories were considered to classify the different biosignals used for HMI control: biopotential, muscle mechanical motion, body motion, and their combinations (hybrid systems). The HMIs were also classified according to their target application by considering six categories: prosthetic control, robotic control, virtual reality control, gesture recognition, communication, and smart environment control. An ever‐growing number of publications has been observed over the last years. Most of the studies (about 67%) pertain to the assistive field, while 20% relate to rehabilitation and 13% to assistance and rehabilitation. A moderate increase can be observed in studies focusing on robotic control, prosthetic control, and gesture recognition in the last decade. In contrast, studies on the other targets experienced only a small increase. Biopotentials are no longer the leading control signals, and the use of muscle mechanical motion signals has experienced a considerable rise, especially in prosthetic control. Hybrid technologies are promising, as they could lead to higher performances. However, they also increase HMIs’ complex-ity, so their usefulness should be carefully evaluated for the specific application

Ongoing temporal dynamics of broadband EEG during movement intention for BCI

Brain Computer Interface (BCI) empowers individuals with severe movement impairing conditions to interact with the computers directly by their thoughts, without the involvement of any motor pathways. Motor-based BCIs can offer intuitive control by merely intending to move. Hence, to develop effective motor-based non-invasive BCIs, it is essential to understand the mechanisms of neural processes involved in motor command generation in electroencephalography (EEG). The EEG consists of complex narrowband oscillatory and broadband arrhythmic processes. However, there is more focus on the oscillations in different frequency bands for studying motor command generation in the literature. The narrowband processes such as event-related (de)synchronisation (ERD/S) and movement-related cortical potential (MRCP) are commonly used for movement detection. Analysis of these narrowband EEG components disregards the information existing in the rest of the frequencies and their dynamics. Hence, this thesis investigates various facets of previously unexplored temporal dynamics of neuronal processes in the broadband arrhythmic EEG to fill the gap in the knowledge of motor command generation on a single trial basis in the BCI framework. The temporal dynamics of the broadband EEG were characterised by the decay of its autocorrelation. The autocorrelation decayed according to the power-law resulting in the longrange temporal correlations (LRTC). The instantaneous ongoing changes in the broadband LRTC were uniquely quantified by the Hurst exponent on very short EEG sliding windows. There was an increase in the temporal dependencies in the EEG leading to slower decay of autocorrelation during the movement and significant increase in the LRTC (p<0.05). Different types of temporal dependencies in the broadband EEG were comprehensively examined further by modelling the long and short-range correlations together using autoregressive fractionally integrated moving average model (ARFIMA). The short-range correlations also changed significantly (p<0.05) during the movement. These ongoing changes in the dynamics of the broadband EEG were able to predict the movement 1 s before its onset with accuracy higher than ERD and MRCP. The LRTCs were robust across participants and did not require determination of participant specific parameters such as most responsive spectral or spatial components

Physical Diagnosis and Rehabilitation Technologies

The book focuses on the diagnosis, evaluation, and assistance of gait disorders; all the papers have been contributed by research groups related to assistive robotics, instrumentations, and augmentative devices

A survey on bio-signal analysis for human-robot interaction

The use of bio-signals analysis in human-robot interaction is rapidly increasing. There is an urgent demand for it in various applications, including health care, rehabilitation, research, technology, and manufacturing. Despite several state-of-the-art bio-signals analyses in human-robot interaction (HRI) research, it is unclear which one is the best. In this paper, the following topics will be discussed: robotic systems should be given priority in the rehabilitation and aid of amputees and disabled people; second, domains of feature extraction approaches now in use, which are divided into three main sections (time, frequency, and time-frequency). The various domains will be discussed, then a discussion of each domain's benefits and drawbacks, and finally, a recommendation for a new strategy for robotic systems

Robotic Platforms for Assistance to People with Disabilities

People with congenital and/or acquired disabilities constitute a great number of dependents today. Robotic platforms to help people with disabilities are being developed with the aim of providing both rehabilitation treatment and assistance to improve their quality of life. A high demand for robotic platforms that provide assistance during rehabilitation is expected because of the health status of the world due to the COVID-19 pandemic. The pandemic has resulted in countries facing major challenges to ensure the health and autonomy of their disabled population. Robotic platforms are necessary to ensure assistance and rehabilitation for disabled people in the current global situation. The capacity of robotic platforms in this area must be continuously improved to benefit the healthcare sector in terms of chronic disease prevention, assistance, and autonomy. For this reason, research about human–robot interaction in these robotic assistance environments must grow and advance because this topic demands sensitive and intelligent robotic platforms that are equipped with complex sensory systems, high handling functionalities, safe control strategies, and intelligent computer vision algorithms. This Special Issue has published eight papers covering recent advances in the field of robotic platforms to assist disabled people in daily or clinical environments. The papers address innovative solutions in this field, including affordable assistive robotics devices, new techniques in computer vision for intelligent and safe human–robot interaction, and advances in mobile manipulators for assistive tasks

Rehabilitation Engineering

Population ageing has major consequences and implications in all areas of our daily life as well as other important aspects, such as economic growth, savings, investment and consumption, labour markets, pensions, property and care from one generation to another. Additionally, health and related care, family composition and life-style, housing and migration are also affected. Given the rapid increase in the aging of the population and the further increase that is expected in the coming years, an important problem that has to be faced is the corresponding increase in chronic illness, disabilities, and loss of functional independence endemic to the elderly (WHO 2008). For this reason, novel methods of rehabilitation and care management are urgently needed. This book covers many rehabilitation support systems and robots developed for upper limbs, lower limbs as well as visually impaired condition. Other than upper limbs, the lower limb research works are also discussed like motorized foot rest for electric powered wheelchair and standing assistance device

Enhancing brain/neural-machine interfaces for upper limb motor restoration in chronic stroke and cervical spinal cord injury

Operation of assistive exoskeletons based on voluntary control of sensorimotor rhythms (SMR, 8-12 Hz) enables intuitive control of finger or arm movements in severe paralysis after chronic stroke or cervical spinal cord injury (SCI). To improve reliability of such systems outside the laboratory, in particular when brain activity is recorded non-invasively with scalp electroencephalography (EEG), a hybrid EEG/electrooculography (EOG) brain/neural-machine interface (B/NMI) was recently introduced. Besides providing assistance, recent studies indicate that repeated use of such systems can trigger neural recovery. However, important prerequisites have to achieved before broader use in clinical settings or everyday life environments is feasible. Current B/NMI systems predominantly restore hand function, but do not allow simultaneous control of more proximal joints for whole-arm motor coordination as required for most stroke survivors suffering from paralysis in the entire upper limb. Besides paralysis, cognitive impairments including post-stroke fatigue due to the brain lesion reduce the capacity to maintain effortful B/NMI control over a longer period of time. This impedes the applicability in daily life assistance and might even limits the efficacy of neurorehabilitation training. In contrast to stroke survivors, tetraplegics due to cervical SCI lack motor function in both hands. Given that most activities of daily living (ADL) involve bimanual manipulation, e.g., to open the lid of a bottle, bilateral exoskeleton control is required but was not shown yet in tetraplegics. To further enhance B/NMI systems, we first investigated whether B/NMI whole-arm exoskeleton control in hemiplegia after chronic stroke is feasible and safe. In contrast to simple grasping, control of more complex tasks involving the entire upper limb was not feasible with established B/NMIs because high- dimensionality of such multiple joint systems exceeds the bandwidth of these interfaces. Thus, we blended B/NMI control with vision-guidance to receive a semiautonomous whole-arm exoskeleton control. Such setup allowed to divide ADL tasks into a sequence of EEG/EOG-triggered sub-tasks reducing complexity for the user. While, for instance, a drinking task was resolved into EOG-induced reaching, lifting and placing back the cup, grasping and releasing movements were based on intuitive SMR control. Feasibility of such shared vision-guided B/NMI control was assumed when executions were initialized within 3 s (fluent control) and a minimum of 75 % of subtasks were executed within that time (reliable control). We showed feasibility in healthy subjects as well as stroke survivors without report of any side effects documenting safe use. Similarly, feasibility and safety of bilateral B/NMI control after cervical SCI was evaluated. To enable bilateral B/NMI control, established EEG-based grasping and EOG-based releasing or stop commands were complemented with a novel EOG command allowing to switch laterality by performing prolonged horizontal eye movements (>1 s) to the left or to the right. Study results with healthy subjects and tetraplegics document fluent initialization of grasping motions below 3 s as well as safe use as unintended grasping could be stopped before a full motion was conducted. Superiority of novel bilateral control was documented by a higher accuracy of up to 22 % in tetraplegics compared to a bilateral control without prolonged EOG command. Lastly, as reliable B/NMI control is cognitively demanding, e.g., by imagining or attempting the desired movements, we investigated whether heart rate variability (HRV) can be used as biomarker to predict declining control performance, which is often reported in stroke survivors due to their cognitive impairments. Referring to the close brain-heart connection, we showed in healthy subjects that a decline in HRV is specific as well as predictive to a decline in B/NMI control performance within a single training session. The predictive link was revealed by a Granger-causality analysis. In conclusion, we could demonstrate important enhancements in B/NMI control paradigms including complex whole-arm exoskeleton control as well as individual performance monitoring within a training session based on HRV. Both achievements contribute to broaden the use as a standard therapy in stroke neurorehabilitation. Especially the predictive characteristic of HRV paves the way for adaptive B/NMI control paradigms to account for individual differences among impaired stroke survivors. Moreover, we also showed feasibility and safety of a novel implementation for bilateral B/NMI control, which is necessary for reliable operation of two hand-exoskeletons for bimanual ADLs after SCI

Sensory integration through the scope of body ownership

Sensory integration is the process by which the brain combines distinct sensory modalities, such that the merged information can be efficiently used to interact with the environment. Body ownership is an example of a subjective experience that emerges through sensory integration. The mechanisms of sensory integration are not yet fully understood. By employing illusions such as the body ownership illusion, where a person falsely perceives an artificial limb as part of their body, brain processes governing sensory integration can be investigated. In this PhD project, a virtual reality platform capable of eliciting a body ownership illusion via accurately timed visuo-tactile stimulation was developed, and used as a tool for studying sensory integration. A threat perception experiment, and an experiment inducing visuo-tactile stimulation with temporal delay were conducted using this platform. Biophysical and behavioural results from this study showed that threat perception and body ownership are not necessarily correlated, but can be viewed as parallel processes within the context of embodiment, and can be observed in distinct neural correlates of brain activity. Based on the results from these studies, it is proposed that the experience of body ownership is not an all-or-nothing, binary experience, but instead, can be considered as a graded experience and having multiple levels

Optimizing Common Spatial Pattern for a Motor Imagerybased BCI by Eigenvector Filteration

One of the fundamental criterion for the successful application of a brain-computer interface (BCI) system is to extract significant features that confine invariant characteristics specific to each brain state. Distinct features play an important role in enabling a computer to associate different electroencephalogram (EEG) signals to different brain states. To ease the workload on the feature extractor and enhance separability between different brain states, the data is often transformed or filtered to maximize separability before feature extraction. The common spatial patterns (CSP) approach can achieve this by linearly projecting the multichannel EEG data into a surrogate data space by the weighted summation of the appropriate channels. However, choosing the optimal spatial filters is very significant in the projection of the data and this has a direct impact on classification. This paper presents an optimized pattern selection method from the CSP filter for improved classification accuracy. Based on the hypothesis that values closer to zero in the CSP filter introduce noise rather than useful information, the CSP filter is modified by analyzing the CSP filter and removing/filtering the degradative or insignificant values from the filter. This hypothesis is tested by comparing the BCI results of eight subjects using the conventional CSP filters and the optimized CSP filter. In majority of the cases the latter produces better performance in terms of the overall classification accuracy