2,367 research outputs found
Multilinear Wavelets: A Statistical Shape Space for Human Faces
We present a statistical model for D human faces in varying expression,
which decomposes the surface of the face using a wavelet transform, and learns
many localized, decorrelated multilinear models on the resulting coefficients.
Using this model we are able to reconstruct faces from noisy and occluded D
face scans, and facial motion sequences. Accurate reconstruction of face shape
is important for applications such as tele-presence and gaming. The localized
and multi-scale nature of our model allows for recovery of fine-scale detail
while retaining robustness to severe noise and occlusion, and is
computationally efficient and scalable. We validate these properties
experimentally on challenging data in the form of static scans and motion
sequences. We show that in comparison to a global multilinear model, our model
better preserves fine detail and is computationally faster, while in comparison
to a localized PCA model, our model better handles variation in expression, is
faster, and allows us to fix identity parameters for a given subject.Comment: 10 pages, 7 figures; accepted to ECCV 201
Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates
The study of cerebral anatomy in developing neonates is of great importance for
the understanding of brain development during the early period of life. This
dissertation therefore focuses on three challenges in the modelling of cerebral
anatomy in neonates during brain development. The methods that have been
developed all use Magnetic Resonance Images (MRI) as source data.
To facilitate study of vascular development in the neonatal period, a set of image
analysis algorithms are developed to automatically extract and model cerebral
vessel trees. The whole process consists of cerebral vessel tracking from
automatically placed seed points, vessel tree generation, and vasculature
registration and matching. These algorithms have been tested on clinical Time-of-
Flight (TOF) MR angiographic datasets.
To facilitate study of the neonatal cortex a complete cerebral cortex segmentation
and reconstruction pipeline has been developed. Segmentation of the neonatal
cortex is not effectively done by existing algorithms designed for the adult brain
because the contrast between grey and white matter is reversed. This causes pixels
containing tissue mixtures to be incorrectly labelled by conventional methods. The
neonatal cortical segmentation method that has been developed is based on a novel
expectation-maximization (EM) method with explicit correction for mislabelled
partial volume voxels. Based on the resulting cortical segmentation, an implicit
surface evolution technique is adopted for the reconstruction of the cortex in
neonates. The performance of the method is investigated by performing a detailed
landmark study.
To facilitate study of cortical development, a cortical surface registration algorithm
for aligning the cortical surface is developed. The method first inflates extracted
cortical surfaces and then performs a non-rigid surface registration using free-form
deformations (FFDs) to remove residual alignment. Validation experiments using
data labelled by an expert observer demonstrate that the method can capture local
changes and follow the growth of specific sulcus
3D time series analysis of cell shape using Laplacian approaches
Background:
Fundamental cellular processes such as cell movement, division or food uptake critically depend on cells being able to change shape. Fast acquisition of three-dimensional image time series has now become possible, but we lack efficient tools for analysing shape deformations in order to understand the real three-dimensional nature of shape changes.
Results:
We present a framework for 3D+time cell shape analysis. The main contribution is three-fold: First, we develop a fast, automatic random walker method for cell segmentation. Second, a novel topology fixing method is proposed to fix segmented binary volumes without spherical topology. Third, we show that algorithms used for each individual step of the analysis pipeline (cell segmentation, topology fixing, spherical parameterization, and shape representation) are closely related to the Laplacian operator. The framework is applied to the shape analysis of neutrophil cells.
Conclusions:
The method we propose for cell segmentation is faster than the traditional random walker method or the level set method, and performs better on 3D time-series of neutrophil cells, which are comparatively noisy as stacks have to be acquired fast enough to account for cell motion. Our method for topology fixing outperforms the tools provided by SPHARM-MAT and SPHARM-PDM in terms of their successful fixing rates. The different tasks in the presented pipeline for 3D+time shape analysis of cells can be solved using Laplacian approaches, opening the possibility of eventually combining individual steps in order to speed up computations
Fast left ventricle tracking using localized anatomical affine optical flow
Fast left ventricle tracking using localized anatomical affine optical flowIn daily clinical cardiology practice, left ventricle (LV) global and regional function assessment is crucial for disease diagnosis, therapy selection, and patient follow-up. Currently, this is still a time-consuming task, spending valuable human resources. In this work, a novel fast methodology for automatic LV tracking is proposed based on localized anatomically constrained affine optical flow. This novel method can be combined to previously proposed segmentation frameworks or manually delineated surfaces at an initial frame to obtain fully delineated datasets and, thus, assess both global and regional myocardial function. Its feasibility and accuracy were investigated in 3 distinct public databases, namely in realistically simulated 3D ultrasound, clinical 3D echocardiography, and clinical cine cardiac magnetic resonance images. The method showed accurate tracking results in all databases, proving its applicability and accuracy for myocardial function assessment. Moreover, when combined to previous state-of-the-art segmentation frameworks, it outperformed previous tracking strategies in both 3D ultrasound and cardiac magnetic resonance data, automatically computing relevant cardiac indices with smaller biases and narrower limits of agreement compared to reference indices. Simultaneously, the proposed localized tracking method showed to be suitable for online processing, even for 3D motion assessment. Importantly, although here evaluated for LV tracking only, this novel methodology is applicable for tracking of other target structures with minimal adaptations.The authors acknowledge funding support from FCT - Fundacao para a Ciência e a Tecnologia, Portugal, and
the European Social Found, European Union, through the Programa Operacional Capital Humano (POCH) in
the scope of the PhD grants SFRH/BD/93443/2013 (S. Queiros) and SFRH/BD/95438/2013 (P. Morais), and
by the project ’PersonalizedNOS (01-0145-FEDER-000013)’ co-funded by Programa Operacional Regional
do Norte (Norte2020) through the European Regional Development Fund (ERDF).info:eu-repo/semantics/publishedVersio
Markerless deformation capture of hoverfly wings using multiple calibrated cameras
This thesis introduces an algorithm for the automated deformation capture of hoverfly
wings from multiple camera image sequences. The algorithm is capable of extracting
dense surface measurements, without the aid of fiducial markers, over an arbitrary number
of wingbeats of hovering flight and requires limited manual initialisation. A novel motion
prediction method, called the ‘normalised stroke model’, makes use of the similarity of adjacent
wing strokes to predict wing keypoint locations, which are then iteratively refined in
a stereo image registration procedure. Outlier removal, wing fitting and further refinement
using independently reconstructed boundary points complete the algorithm. It was tested
on two hovering data sets, as well as a challenging flight manoeuvre. By comparing the
3-d positions of keypoints extracted from these surfaces with those resulting from manual
identification, the accuracy of the algorithm is shown to approach that of a fully manual
approach. In particular, half of the algorithm-extracted keypoints were within 0.17mm of
manually identified keypoints, approximately equal to the error of the manual identification
process. This algorithm is unique among purely image based flapping flight studies in the
level of automation it achieves, and its generality would make it applicable to wing tracking
of other insects
Visualization and Correction of Automated Segmentation, Tracking and Lineaging from 5-D Stem Cell Image Sequences
Results: We present an application that enables the quantitative analysis of
multichannel 5-D (x, y, z, t, channel) and large montage confocal fluorescence
microscopy images. The image sequences show stem cells together with blood
vessels, enabling quantification of the dynamic behaviors of stem cells in
relation to their vascular niche, with applications in developmental and cancer
biology. Our application automatically segments, tracks, and lineages the image
sequence data and then allows the user to view and edit the results of
automated algorithms in a stereoscopic 3-D window while simultaneously viewing
the stem cell lineage tree in a 2-D window. Using the GPU to store and render
the image sequence data enables a hybrid computational approach. An
inference-based approach utilizing user-provided edits to automatically correct
related mistakes executes interactively on the system CPU while the GPU handles
3-D visualization tasks. Conclusions: By exploiting commodity computer gaming
hardware, we have developed an application that can be run in the laboratory to
facilitate rapid iteration through biological experiments. There is a pressing
need for visualization and analysis tools for 5-D live cell image data. We
combine accurate unsupervised processes with an intuitive visualization of the
results. Our validation interface allows for each data set to be corrected to
100% accuracy, ensuring that downstream data analysis is accurate and
verifiable. Our tool is the first to combine all of these aspects, leveraging
the synergies obtained by utilizing validation information from stereo
visualization to improve the low level image processing tasks.Comment: BioVis 2014 conferenc
AFFECT-PRESERVING VISUAL PRIVACY PROTECTION
The prevalence of wireless networks and the convenience of mobile cameras enable many new video applications other than security and entertainment. From behavioral diagnosis to wellness monitoring, cameras are increasing used for observations in various educational and medical settings. Videos collected for such applications are considered protected health information under privacy laws in many countries. Visual privacy protection techniques, such as blurring or object removal, can be used to mitigate privacy concern, but they also obliterate important visual cues of affect and social behaviors that are crucial for the target applications. In this dissertation, we propose to balance the privacy protection and the utility of the data by preserving the privacy-insensitive information, such as pose and expression, which is useful in many applications involving visual understanding.
The Intellectual Merits of the dissertation include a novel framework for visual privacy protection by manipulating facial image and body shape of individuals, which: (1) is able to conceal the identity of individuals; (2) provide a way to preserve the utility of the data, such as expression and pose information; (3) balance the utility of the data and capacity of the privacy protection.
The Broader Impacts of the dissertation focus on the significance of privacy protection on visual data, and the inadequacy of current privacy enhancing technologies in preserving affect and behavioral attributes of the visual content, which are highly useful for behavior observation in educational and medical settings. This work in this dissertation represents one of the first attempts in achieving both goals simultaneously
Automatic generation of statistical pose and shape models for articulated joints
Statistical analysis of motion patterns of body joints is potentially useful for detecting and quantifying pathologies. However, building a statistical motion model across different subjects remains a challenging task, especially for a complex joint like the wrist. We present a novel framework for simultaneous registration and segmentation of multiple 3-D (CT or MR) volumes of different subjects at various articulated positions. The framework starts with a pose model generated from 3-D volumes captured at different articulated positions of a single subject (template). This initial pose model is used to register the template volume to image volumes from new subjects. During this process, the Grow-Cut algorithm is used in an iterative refinement of the segmentation of the bone along with the pose parameters. As each new subject is registered and segmented, the pose model is updated, improving the accuracy of successive registrations. We applied the algorithm to CT images of the wrist from 25 subjects, each at five different wrist positions and demonstrated that it performed robustly and accurately. More importantly, the resulting segmentations allowed a statistical pose model of the carpal bones to be generated automatically without interaction. The evaluation results show that our proposed framework achieved accurate registration with an average mean target registration error of mm. The automatic segmentation results also show high consistency with the ground truth obtained semi-automatically. Furthermore, we demonstrated the capability of the resulting statistical pose and shape models by using them to generate a measurement tool for scaphoid-lunate dissociation diagnosis, which achieved 90% sensitivity and specificity
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