Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field.

Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. The gray-level images of nuclear chromatin are modelled as random fields. We used two-dimensional isotropic generalized Cauchy field to characterize local self-similarity and global long-range dependence behaviors in the image spatial data. Generalized Cauchy field allows the description of fractal behavior inferred from fractal dimension and the long-range dependence inferred from correlation exponent to be carried out independently. We demonstrated the usefulness of locally self-similar random fields with long-range dependence for modelling chromatin condensation

Visiting Power Laws in Cyber-Physical Networking Systems

Cyber-physical networking systems (CPNSs) are made up of various physical systems that are heterogeneous in nature. Therefore, exploring universalities in CPNSs for either data or systems is desired in its fundamental theory. This paper is in the aspect of data, aiming at addressing that power laws may yet be a universality of data in CPNSs. The contributions of this paper are in triple folds. First, we provide a short tutorial about power laws. Then, we address the power laws related to some physical systems. Finally, we discuss that power-law-type data may be governed by stochastically differential equations of fractional order. As a side product, we present the point of view that the upper bound of data flow at large-time scaling and the small one also follows power laws

Hölder Scales of Sea Level

The statistics of sea level is essential in the field of geosciences, ranging from ocean dynamics to climates. The fractal properties of sea level, such as long-range dependence (LRD) or long memory, 1/f noise behavior, and self-similarity (SS), are known. However, the description of its multiscale behavior as well as local roughness with the Hölder exponent h(t) from a view of multifractional Brownian motion (mBm) is rarely reported, to the best of our knowledge. In this research, we will exhibit that there is the multiscale property of sea level based on h(t)s of sea level data recorded by the National Data Buoy Center (NDBC) at six stations in the Florida and Eastern Gulf of Mexico. The contributions of this paper are twofold as follows. (i) Hölder exponent of sea level may not change with time considerably at small time scale, for example, daily time scale, but it varies significantly at large time scale, such as at monthly time scale. (ii) The dispersion of the Hölder exponents of sea level may be different at different stations. This implies that the Hölder roughness of sea level may be spatial dependent

Cell and cell-aggregate mechanics: remodelling, growth and interaction with the extracellular environment.

The scope of this dissertation is to give a contribution to the understanding of the mathematical description of cell and cellular aggregate mechanics, focusing on remodelling and growth processes which occur inside living structures and on the interactions among cells and the extracellular environment, during the process of cell migration

Radiobiology Textbook:Space Radiobiology

The study of the biologic effects of space radiation is considered a “hot topic,” with increased interest in the past years. In this chapter, the unique characteristics of the space radiation environment will be covered, from their history, characterization, and biological effects to the research that has been and is being conducted in the field. After a short introduction, you will learn the origin and characterization of the different types of space radiation and the use of mathematical models for the prediction of the radiation doses during different mission scenarios and estimate the biological risks due to this exposure. Following this, the acute, chronic, and late effects of radiation exposure in the human body are discussed before going into the detailed biomolecular changes affecting cells and tissues, and in which ways they differ from other types of radiation exposure. The next sections of this chapter are dedicated to the vast research that has been developed through the years concerning space radiation biology, from small animals to plant models and 3D cell cultures, the use of extremophiles in the study of radiation resistance mechanisms to the importance of ground-based irradiation facilities to simulate and study the space environment

Pameran Reka Cipta, Penyelidikan dan Inovasi (PRPI) 2009

PRPI 2009 kini telah memasuki tahun penganjurannya yang ke-7. Pameran penyelidikan di UPM telah bermula sejak tahun 1997 semasa Exhibition & Seminar Harnessing for Industry Advantage. Pada tahun 2002, Pameran Reka Cipta dan Penyelidikan (PRP) buat pertama kali telah diadakan dengan menggunakan konsep pertandingan hasil projek penyelidikan yang telah dijalankan oleh para penyelidik UPM. Kejayaan penganjuran PRP 2002 telah merintis usaha untuk menjadikannya sebagai aktiviti tahunan UPM dan ianya terus berkembang sejajar dengan nama baharunya yang ditukar kepada Pameran Reka Cipta, Penyelidikan dan Inovasi yang bermula penganjurannya pada tahun 2005. Sebagai kesinambungan daripada kejayaan penganjuran PRPI 2006, 2007 dan 2008 yang lalu dan status UPM sebagai salah sebuah Universiti Penyelidikan, PRPI 2009 kali ini yang merupakan pameran penyelidikan yang terbesar di UPM terus dilaksanakan dengan aspirasi dan semangat yang lebih jitu. Pameran ini juga menjadi pelantar kepada para penyelidik untuk mengenengahkan hasil penyelidikan yang dijalankan dan penemuan baharu kepada umum. Di samping itu ianya juga menjadi penanda aras terhadap kualiti sesuatu projek penyelidikan bagi melayakkan para penyelidik UPM untuk menyertai pameran di peringkat kebangsaan dan seterusnya antarabangsa. Adalah diharapkan pelaksanaan PRPI 2009 ini akan dapat menyemarakkan budaya penyelidikan di kalangan staf dan juga pelajar UPM sekaligus menjadikan UPM sebagai Universiti Penyelidikan yang cemerlang di negara ini