Investigating microstructural variation in the human hippocampus using non-negative matrix factorization

In this work we use non-negative matrix factorization to identify patterns of microstructural variance in the human hippocampus. We utilize high-resolution structural and diffusion magnetic resonance imaging data from the Human Connectome Project to query hippocampus microstructure on a multivariate, voxelwise basis. Application of non-negative matrix factorization identifies spatial components (clusters of voxels sharing similar covariance patterns), as well as subject weightings (individual variance across hippocampus microstructure). By assessing the stability of spatial components as well as the accuracy of factorization, we identified 4 distinct microstructural components. Furthermore, we quantified the benefit of using multiple microstructural metrics by demonstrating that using three microstructural metrics (T1-weighted/T2-weighted signal, mean diffusivity and fractional anisotropy) produced more stable spatial components than when assessing metrics individually. Finally, we related individual subject weightings to demographic and behavioural measures using a partial least squares analysis. Through this approach we identified interpretable relationships between hippocampus microstructure and demographic and behavioural measures. Taken together, our work suggests non-negative matrix factorization as a spatially specific analytical approach for neuroimaging studies and advocates for the use of multiple metrics for data-driven component analyses

Distance Measures for Reduced Ordering Based Vector Filters

Reduced ordering based vector filters have proved successful in removing long-tailed noise from color images while preserving edges and fine image details. These filters commonly utilize variants of the Minkowski distance to order the color vectors with the aim of distinguishing between noisy and noise-free vectors. In this paper, we review various alternative distance measures and evaluate their performance on a large and diverse set of images using several effectiveness and efficiency criteria. The results demonstrate that there are in fact strong alternatives to the popular Minkowski metrics

Energy rating of a water pumping station using multivariate analysis

Among water management policies, the preservation and the saving of energy demand in water supply and treatment systems play key roles. When focusing on energy, the customary metric to determine the performance of water supply systems is linked to the definition of component-based energy indicators. This approach is unfit to account for interactions occurring among system elements or between the system and its environment. On the other hand, the development of information technology has led to the availability of increasing large amount of data, typically gathered from distributed sensor networks in so-called smart grids. In this context, data intensive methodologies address the possibility of using complex network modeling approaches, and advocate the issues related to the interpretation and analysis of large amount of data produced by smart sensor networks. In this perspective, the present work aims to use data intensive techniques in the energy analysis of a water management network. The purpose is to provide new metrics for the energy rating of the system and to be able to provide insights into the dynamics of its operations. The study applies neural network as a tool to predict energy demand, when using flowrate and vibration data as predictor variables