Artifact-Aware Analogue/Mixed-Signal Front-Ends for Neural Recording Applications

This paper presents a brief review of techniques to overcome the problems associated with artifacts in analog frontends for neural recording applications. These techniques are employed for handling Common-Mode (CM) Differential-Mode (DM) artifacts and include techniques such as Average Template Subtraction, Channel Blanking or Blind Adaptive Stimulation Artifact Rejection (ASAR), among others. Additionally, a new technique for DM artifacts compression is proposed. It allows to compress these artifacts to the requirements of the analog frontend and, afterwards, it allows to reconstruct the whole artifact or largely suppress it.Ministerio de Economía y Empresa TEC2016-80923-

Flexible and stretchable electronics for wearable healthcare

Measuring the quality of human health and well-being is one of the key growth areas in our society. Preferably, these measurements are done as unobtrusive as possible. These sensoric devices are then to be integrated directly on the human body as a patch or integrated into garments. This requires the devices to be very thin, flexible and sometimes even stretchable. An overview will be given of recent technology developments in this domain and concrete application examples will be shown

Two improved methods for testing ADC parametric faults by digital input signals

In this paper, two improved methods are presented extending our previous work. The first one improves the results by adjusting the voltage levels of the input pulse wave stimulus. Compared with the sine wave input stimulus, the four-level pulse wave can detect even more faulty cases with the offset faults. The second one improves the results by calculating the similarity of the output spectra between the golden devices and the DUTs. Compared with the previous method [10], it is less sensitive to the jitter and the change of the rise/fall time of the input pulse wave stimulus. In these two methods, a number of golden devices are tested at first to obtain the fault-free range. At last, a signature result is obtained from both methods. It can filter out the faulty devices in a quick way before testing the specific values of the conventional dynamic and static parameters

Enhanced Sensitivity of CMOS Image Sensors by Stacked Diodes

We have investigated and compared the performance of photodiodes built with stacked p/n junctions operating in parallel versus conventional ones made with single p/n junctions. We propose a method to characterize and compare photodiodes sensitivity. For this purpose, a dedicated chip in the standard AMS 180-nm HV technology has been fabricated. Four different sensor structures were implemented and compared. Experimental results are provided. Measurements show sensitivity enhancement ranging from 55% to 70% within the 500-1100 nm spectral region. The larger increment is happening in the near infrared band (up to 62%). Such results make stacked photodiodes suitable candidates for the implementation of photosensors in vision chips designed for standard CMOS technologies.Ministerio de Economía y Competitividad TEC2012-33634, TEC2015-66878- C3-1-RJunta de Andalucía TIC 2012-2338Office of Naval Research (USA) N00014141035

Phase Synchronization Operator for On-Chip Brain Functional Connectivity Computation

This paper presents an integer-based digital processor for the calculation of phase synchronization between two neural signals. It is based on the measurement of time periods between two consecutive minima. The simplicity of the approach allows for the use of elementary digital blocks, such as registers, counters, and adders. The processor, fabricated in a 0.18- μ m CMOS process, only occupies 0.05 mm 2 and consumes 15 nW from a 0.5 V supply voltage at a signal input rate of 1024 S/s. These low-area and low-power features make the proposed processor a valuable computing element in closed-loop neural prosthesis for the treatment of neural disorders, such as epilepsy, or for assessing the patterns of correlated activity in neural assemblies through the evaluation of functional connectivity maps.Ministerio de Economía y Competitividad TEC2016-80923-POffice of Naval Research (USA) N00014-19-1-215

A 32 Input Multiplexed Channel Analog Front-End with Spatial Delta Encoding Technique and Differential Artifacts Compression

This paper describes a low-noise, low-power and high dynamic range analog front-end intended for sensing neural signals. In order to reduce interface area, a 32-channel multiplexer is implemented on circuit input. Furthermore, a spatial delta encoding is proposed to compress the signal range. A differential artifact compression algorithm is implemented to avoid saturation in the signal path, thus enabling reconstruct or suppressing artifacts in digital domain. The proposed design has been implemented using 0.18 μm TSMC technology. Experimental results shows a power consumption per channel of 1.0 μW, an input referred noise of 1.1 μVrms regarding the bandwidth of interest and a dynamic range of 91 dB.Ministerio de Economía y Competitividad TEC2016-80923-POffice of Naval Research ONR N00014- 19-1-215