20,338 research outputs found
Prediction of peptides binding to MHC class I alleles by partial periodic pattern mining
MHC (Major Histocompatibility Complex) is a key player in the immune response of an organism. It is important to be able to predict which antigenic peptides will bind to a spe-cific MHC allele and which will not, creating possibilities for controlling immune response and for the applications of immunotherapy. However a problem encountered in the computational binding prediction methods for MHC class I is the presence of bulges and loops in the peptides, changing the total length. Most machine learning methods in use to-day require the sequences to be of same length to success-fully mine the binding motifs. We propose the use of time-based data mining methods in motif mining to be able to mine motifs position-independently. Also, the information for both binding and non-binding peptides are used on the contrary to the other methods which only rely on binding peptides. The prediction results are between 70-80% for the tested alleles
ANTIDS: Self-Organized Ant-based Clustering Model for Intrusion Detection System
Security of computers and the networks that connect them is increasingly
becoming of great significance. Computer security is defined as the protection
of computing systems against threats to confidentiality, integrity, and
availability. There are two types of intruders: the external intruders who are
unauthorized users of the machines they attack, and internal intruders, who
have permission to access the system with some restrictions. Due to the fact
that it is more and more improbable to a system administrator to recognize and
manually intervene to stop an attack, there is an increasing recognition that
ID systems should have a lot to earn on following its basic principles on the
behavior of complex natural systems, namely in what refers to
self-organization, allowing for a real distributed and collective perception of
this phenomena. With that aim in mind, the present work presents a
self-organized ant colony based intrusion detection system (ANTIDS) to detect
intrusions in a network infrastructure. The performance is compared among
conventional soft computing paradigms like Decision Trees, Support Vector
Machines and Linear Genetic Programming to model fast, online and efficient
intrusion detection systems.Comment: 13 pages, 3 figures, Swarm Intelligence and Patterns (SIP)- special
track at WSTST 2005, Muroran, JAPA
AI Solutions for MDS: Artificial Intelligence Techniques for Misuse Detection and Localisation in Telecommunication Environments
This report considers the application of Articial Intelligence (AI) techniques to
the problem of misuse detection and misuse localisation within telecommunications
environments. A broad survey of techniques is provided, that covers inter alia
rule based systems, model-based systems, case based reasoning, pattern matching,
clustering and feature extraction, articial neural networks, genetic algorithms, arti
cial immune systems, agent based systems, data mining and a variety of hybrid
approaches. The report then considers the central issue of event correlation, that
is at the heart of many misuse detection and localisation systems. The notion of
being able to infer misuse by the correlation of individual temporally distributed
events within a multiple data stream environment is explored, and a range of techniques,
covering model based approaches, `programmed' AI and machine learning
paradigms. It is found that, in general, correlation is best achieved via rule based approaches,
but that these suffer from a number of drawbacks, such as the difculty of
developing and maintaining an appropriate knowledge base, and the lack of ability
to generalise from known misuses to new unseen misuses. Two distinct approaches
are evident. One attempts to encode knowledge of known misuses, typically within
rules, and use this to screen events. This approach cannot generally detect misuses
for which it has not been programmed, i.e. it is prone to issuing false negatives.
The other attempts to `learn' the features of event patterns that constitute normal
behaviour, and, by observing patterns that do not match expected behaviour, detect
when a misuse has occurred. This approach is prone to issuing false positives,
i.e. inferring misuse from innocent patterns of behaviour that the system was not
trained to recognise. Contemporary approaches are seen to favour hybridisation,
often combining detection or localisation mechanisms for both abnormal and normal
behaviour, the former to capture known cases of misuse, the latter to capture
unknown cases. In some systems, these mechanisms even work together to update
each other to increase detection rates and lower false positive rates. It is concluded
that hybridisation offers the most promising future direction, but that a rule or state
based component is likely to remain, being the most natural approach to the correlation
of complex events. The challenge, then, is to mitigate the weaknesses of
canonical programmed systems such that learning, generalisation and adaptation
are more readily facilitated
Application of an AIS to the problem of through life health management of remotely piloted aircraft
The operation of RPAS includes a cognitive problem for the operators(Pilots,
maintainers, ,managers, and the wider organization) to effectively maintain their situational
awareness of the aircraft and predict its health state. This has a large impact on their ability
to successfully identify faults and manage systems during operations. To overcome these
system deficiencies an asset health management system that integrates more cognitive
abilities to aid situational awareness could prove beneficial. This paper outlines an artificial
immune system (AIS) approach that could meet these challenges and an experimental
method within which to evaluate it
Passively mode-locked laser using an entirely centred erbium-doped fiber
This paper describes the setup and experimental results for an entirely centred erbium-doped fiber laser with passively mode-locked output. The gain medium of the ring laser cavity configuration comprises a 3 m length of two-core optical fiber, wherein an undoped outer core region of 9.38 μm diameter surrounds a 4.00 μm diameter central core region doped with erbium ions at 400 ppm concentration. The generated stable soliton mode-locking output has a central wavelength of 1533 nm and pulses that yield an average output power of 0.33 mW with a pulse energy of 31.8 pJ. The pulse duration is 0.7 ps and the measured output repetition rate of 10.37 MHz corresponds to a 96.4 ns pulse spacing in the pulse train
Application of artificial neural network in market segmentation: A review on recent trends
Despite the significance of Artificial Neural Network (ANN) algorithm to
market segmentation, there is a need of a comprehensive literature review and a
classification system for it towards identification of future trend of market
segmentation research. The present work is the first identifiable academic
literature review of the application of neural network based techniques to
segmentation. Our study has provided an academic database of literature between
the periods of 2000-2010 and proposed a classification scheme for the articles.
One thousands (1000) articles have been identified, and around 100 relevant
selected articles have been subsequently reviewed and classified based on the
major focus of each paper. Findings of this study indicated that the research
area of ANN based applications are receiving most research attention and self
organizing map based applications are second in position to be used in
segmentation. The commonly used models for market segmentation are data mining,
intelligent system etc. Our analysis furnishes a roadmap to guide future
research and aid knowledge accretion and establishment pertaining to the
application of ANN based techniques in market segmentation. Thus the present
work will significantly contribute to both the industry and academic research
in business and marketing as a sustainable valuable knowledge source of market
segmentation with the future trend of ANN application in segmentation.Comment: 24 pages, 7 figures,3 Table
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Disease modelling using evolved discriminate function
Precocious diagnosis increases the survival time and patient quality of life. It is a binary classification, exhaustively studied in the literature. This paper innovates proposing the application of genetic programming to obtain a discriminate function. This function contains the disease dynamics used to classify the patients with as little false negative diagnosis as possible. If its value is greater than zero then it means that the patient is ill, otherwise healthy. A graphical representation is proposed to show the influence of each dataset attribute in the discriminate function. The experiment deals with Breast Cancer and Thrombosis & Collagen diseases diagnosis. The main conclusion is that the discriminate function is able to classify the patient using numerical clinical data, and the graphical representation displays patterns that allow understanding of the model
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