11,877 research outputs found
Aggregating Content and Network Information to Curate Twitter User Lists
Twitter introduced user lists in late 2009, allowing users to be grouped
according to meaningful topics or themes. Lists have since been adopted by
media outlets as a means of organising content around news stories. Thus the
curation of these lists is important - they should contain the key information
gatekeepers and present a balanced perspective on a story. Here we address this
list curation process from a recommender systems perspective. We propose a
variety of criteria for generating user list recommendations, based on content
analysis, network analysis, and the "crowdsourcing" of existing user lists. We
demonstrate that these types of criteria are often only successful for datasets
with certain characteristics. To resolve this issue, we propose the aggregation
of these different "views" of a news story on Twitter to produce more accurate
user recommendations to support the curation process
Early detection of biochemically occult autonomous thyroid nodules
Objective: Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism,
but may exist even in the presence of normal TSH. This study was aimed at comparing the rate of autonomously
functioning areas and their cardiac sequelae in patients with nodular goitre studied with the usual and a
novel approach.
Design and methods: In total 490 adult outpatients with thyroid nodular goitre, living in a mild iodine-deficient
area, were selected in our referral centre for thyroid diseases from 2009 to 2014 on the basis of a suspicion of thyroid
functional autonomy. They were divided in three groups according to a non-conventional approach (excessive
response to thyroxine treatment: group 1) or conventional approach (low/normal TSH with clinical suspicion or low
TSH: groups 2 and 3). All patients of the study with the suspicion of thyroid functional autonomy underwent thyroid
scan with radioactive iodine (I131) uptake (RAIU).
Results: The percentage of confirmed thyroid functional autonomy was 319/490, being significantly higher in group
3 than in groups 1 and 2 (81.5 vs 64.7 vs 52.6%; chi-square P < 0.0001). However, the diagnosis with non-conventional
approach was made at a significant earlier age (P < 0.0001). Cardiac arrhythmias as well as atrial fibrillation were
similarly detected by conventional and non-conventional approaches (chi-square test: P = 0.2537; P = 0.8425).
Conclusions: The hyper-responsiveness to thyroxine treatment should induce the suspicion of thyroid functional
autonomy at an early stage, allowing to detect autonomous functioning areas in apparently euthyroid patients
Attention-deficit/hyperactivity disorder and brain metabolites from proton magnetic resonance spectroscopy : a systematic review and meta-analysis protocol
Despite major advances in the study of the brain, investigations on neurochemistry in vivo still lack the solid ground of more established methods, such as structural and functional magnetic resonance imaging. Proton magnetic resonance spectroscopy (MRS) is a technique that might potentially fill in this gap. Nevertheless, studies using this approach feature great methodological heterogeneity, such as varying voxel of choice, differences on emphasized metabolites, and absence of a standardized unit. In this study, we present a methodology for creating a systematic review and meta-analysis for this kind of scientific evidence using the prototypical case of attention-deficit/hyperactivity disorder
Requirements engineering: a review and research agenda
This paper reviews the area of requirements engineering. It
outlines the key concerns to which attention should be
devoted by both practitioners, who wish to "reengineer" their
development processes, and academics, seeking intellectual
challenges. It presents an assessment of the state-of-the-art
and draws conclusions in the form of a research agenda
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