3,331 research outputs found

    Information maps: tools for document exploration

    Get PDF

    ARIANA: Adaptive Robust and Integrative Analysis for finding Novel Associations

    Get PDF
    The effective mining of biological literature can provide a range of services such as hypothesis-generation, semantic-sensitive information retrieval, and knowledge discovery, which can be important to understand the confluence of different diseases, genes, and risk factors. Furthermore, integration of different tools at specific levels could be valuable. The main focus of the dissertation is developing and integrating tools in finding network of semantically related entities. The key contribution is the design and implementation of an Adaptive Robust and Integrative Analysis for finding Novel Associations. ARIANA is a software architecture and a web-based system for efficient and scalable knowledge discovery. It integrates semantic-sensitive analysis of text-data through ontology-mapping with database search technology to ensure the required specificity. ARIANA was prototyped using the Medical Subject Headings ontology and PubMed database and has demonstrated great success as a dynamic-data-driven system. ARIANA has five main components: (i) Data Stratification, (ii) Ontology-Mapping, (iii) Parameter Optimized Latent Semantic Analysis, (iv) Relevance Model and (v) Interface and Visualization. The other contribution is integration of ARIANA with Online Mendelian Inheritance in Man database, and Medical Subject Headings ontology to provide gene-disease associations. Empirical studies produced some exciting knowledge discovery instances. Among them was the connection between the hexamethonium and pulmonary inflammation and fibrosis. In 2001, a research study at John Hopkins used the drug hexamethonium on a healthy volunteer that ended in a tragic death due to pulmonary inflammation and fibrosis. This accident might have been prevented if the researcher knew of published case report. Since the original case report in 1955, there has not been any publications regarding that association. ARIANA extracted this knowledge even though its database contains publications from 1960 to 2012. Out of 2,545 concepts, ARIANA ranked “Scleroderma, Systemic”, “Neoplasms, Fibrous Tissue”, “Pneumonia”, “Fibroma”, and “Pulmonary Fibrosis” as the 13th, 16th, 38th, 174th and 257th ranked concept respectively. The researcher had access to such knowledge this drug would likely not have been used on healthy subjects.In today\u27s world where data and knowledge are moving away from each other, semantic-sensitive tools such as ARIANA can bridge that gap and advance dissemination of knowledge

    Cognition-based approaches for high-precision text mining

    Get PDF
    This research improves the precision of information extraction from free-form text via the use of cognitive-based approaches to natural language processing (NLP). Cognitive-based approaches are an important, and relatively new, area of research in NLP and search, as well as linguistics. Cognitive approaches enable significant improvements in both the breadth and depth of knowledge extracted from text. This research has made contributions in the areas of a cognitive approach to automated concept recognition in. Cognitive approaches to search, also called concept-based search, have been shown to improve search precision. Given the tremendous amount of electronic text generated in our digital and connected world, cognitive approaches enable substantial opportunities in knowledge discovery. The generation and storage of electronic text is ubiquitous, hence opportunities for improved knowledge discovery span virtually all knowledge domains. While cognition-based search offers superior approaches, challenges exist due to the need to mimic, even in the most rudimentary way, the extraordinary powers of human cognition. This research addresses these challenges in the key area of a cognition-based approach to automated concept recognition. In addition it resulted in a semantic processing system framework for use in applications in any knowledge domain. Confabulation theory was applied to the problem of automated concept recognition. This is a relatively new theory of cognition using a non-Bayesian measure, called cogency, for predicting the results of human cognition. An innovative distance measure derived from cogent confabulation and called inverse cogency, to rank order candidate concepts during the recognition process. When used with a multilayer perceptron, it improved the precision of concept recognition by 5% over published benchmarks. Additional precision improvements are anticipated. These research steps build a foundation for cognition-based, high-precision text mining. Long-term it is anticipated that this foundation enables a cognitive-based approach to automated ontology learning. Such automated ontology learning will mimic human language cognition, and will, in turn, enable the practical use of cognitive-based approaches in virtually any knowledge domain --Abstract, page iii

    Knowledge management research trends : an analysis of an academic journal

    Get PDF
    Abstract: This paper discusses information and knowledge management (IKM) research trends, based on the abstracts, titles and keywords of original research articles published in the South African Journal of Information Management (SAJIM) between 1999 and 2017. Leximancer, a natural language analysis software tool, was employed to examine the titles, abstracts and keywords of articles published in this journal. The findings of this paper report on the evolution of the field of IKM research over 19 years of publication, and compares the findings to global trends in IKM research

    Use of Semantic Technology to Create Curated Data Albums

    Get PDF
    One of the continuing challenges in any Earth science investigation is the discovery and access of useful science content from the increasingly large volumes of Earth science data and related information available online. Current Earth science data systems are designed with the assumption that researchers access data primarily by instrument or geophysical parameter. Those who know exactly the data sets they need can obtain the specific files using these systems. However, in cases where researchers are interested in studying an event of research interest, they must manually assemble a variety of relevant data sets by searching the different distributed data systems. Consequently, there is a need to design and build specialized search and discovery tools in Earth science that can filter through large volumes of distributed online data and information and only aggregate the relevant resources needed to support climatology and case studies. This paper presents a specialized search and discovery tool that automatically creates curated Data Albums. The tool was designed to enable key elements of the search process such as dynamic interaction and sense-making. The tool supports dynamic interaction via different modes of interactivity and visual presentation of information. The compilation of information and data into a Data Album is analogous to a shoebox within the sense-making framework. This tool automates most of the tedious information/data gathering tasks for researchers. Data curation by the tool is achieved via an ontology-based, relevancy ranking algorithm that filters out non-relevant information and data. The curation enables better search results as compared to the simple keyword searches provided by existing data systems in Earth science

    Use of Semantic Technology to Create Curated Data Albums

    Get PDF
    One of the continuing challenges in any Earth science investigation is the discovery and access of useful science content from the increasingly large volumes of Earth science data and related information available online. Current Earth science data systems are designed with the assumption that researchers access data primarily by instrument or geophysical parameter. Those who know exactly the data sets they need can obtain the specific files using these systems. However, in cases where researchers are interested in studying an event of research interest, they must manually assemble a variety of relevant data sets by searching the different distributed data systems. Consequently, there is a need to design and build specialized search and discover tools in Earth science that can filter through large volumes of distributed online data and information and only aggregate the relevant resources needed to support climatology and case studies. This paper presents a specialized search and discovery tool that automatically creates curated Data Albums. The tool was designed to enable key elements of the search process such as dynamic interaction and sense-making. The tool supports dynamic interaction via different modes of interactivity and visual presentation of information. The compilation of information and data into a Data Album is analogous to a shoebox within the sense-making framework. This tool automates most of the tedious information/data gathering tasks for researchers. Data curation by the tool is achieved via an ontology-based, relevancy ranking algorithm that filters out nonrelevant information and data. The curation enables better search results as compared to the simple keyword searches provided by existing data systems in Earth science
    corecore