INTEGRATED MODELING AND MONITORING FOR A HEALTHY AND SUSTAINABLE BUILDING ENVIRONMENT

The transmission of airborne diseases indoors is a significant challenge to public health. Buildings are hotspots for viral transmission, which can result in adverse effects on human health and quality of life, especially considering that individuals spend approximately 87% of their time indoors. The emergence of the COVID-19 pandemic has highlighted the importance of considering health aspects during the development of sustainable built environments. Consequently, maintaining a healthy, sustainable, and comfortable built environment represents a major challenge for facilities management teams. However, research on the infection risks associated with emerging pandemics is still in its infancy, and the effectiveness of intervention strategies remains uncertain. Furthermore, the complex interplay between health, energy consumption, and human comfort remains poorly understood, impeding the development of comprehensive control strategies that encompass all three critical dimensions of building sustainability. In addition, existing technologies have limitations to conduct real-time monitoring, while current communication methods between occupants and facilities management teams suffer from a lack of effectiveness, user-friendliness, and informativeness. These deficiencies hinder their ability to address the pressing needs of occupants during pandemics. To address these challenges, this dissertation proposes a convergent framework that integrates modeling, simulation, and monitoring methodologies for the development and maintenance of a sustainable built environment. Airborne transmission risks were first modeled and estimated under different epidemic scenarios, allowing for the evaluation of various intervention strategies. Facility data was then used to develop methods for modeling and simulating the dimensions of energy consumption and thermal comfort, allowing for the identification of tradeoff relationships among health, energy, and comfort, and quantitatively analyzing the impact of indoor environments through HVAC control strategies on the three major dimensions. Finally, an integrated platform was developed to enable the real-time assessment of health, energy, and comfort, including monitoring, visualization, and conversational communication functionalities. The developed framework thus encompasses modeling, simulation, monitoring, and communication capabilities and can be widely adopted by facility management teams, providing insights and guidance to governments and policymakers based on their specific needs. The applicability of the framework extends beyond specific pandemics and can be used to address a broader range of infectious diseases

Adaptive Communications for Next Generation Broadband Wireless Access Systems

Un dels aspectes claus en el disseny i gestió de les xarxes sense fils d'accés de banda ampla és l'ús eficient dels recursos radio. Des del punt de vista de l'operador, l'ample de banda és un bé escàs i preuat que s´ha d'explotar i gestionar de la forma més eficient possible tot garantint la qualitat del servei que es vol proporcionar. Per altra banda, des del punt de vista del usuari, la qualitat del servei ofert ha de ser comparable al de les xarxes fixes, requerint així un baix retard i una baixa pèrdua de paquets per cadascun dels fluxos de dades entre la xarxa i l'usuari. Durant els darrers anys s´han desenvolupat nombroses tècniques i algoritmes amb l'objectiu d'incrementar l'eficiència espectral. Entre aquestes tècniques destaca l'ús de múltiples antenes al transmissor i al receptor amb l'objectiu de transmetre diferents fluxos de dades simultaneament sense necessitat d'augmentar l'ample de banda. Per altra banda, la optimizació conjunta de la capa d'accés al medi i la capa física (fent ús de l'estat del canal per tal de gestionar de manera optima els recursos) també permet incrementar sensiblement l'eficiència espectral del sistema.L'objectiu d'aquesta tesi és l'estudi i desenvolupament de noves tècniques d'adaptació de l'enllaç i gestió dels recursos ràdio aplicades sobre sistemes d'accés ràdio de propera generació (Beyond 3G). Els estudis realitzats parteixen de la premissa que el transmisor coneix (parcialment) l'estat del canal i que la transmissió es realitza fent servir un esquema multiportadora amb múltiples antenes al transmisor i al receptor. En aquesta tesi es presenten dues línies d'investigació, la primera per casos d'una sola antenna a cada banda de l'enllaç, i la segona en cas de múltiples antenes. En el cas d'una sola antena al transmissor i al receptor, un nou esquema d'assignació de recursos ràdio i priorització dels paquets (scheduling) és proposat i analitzat integrant totes dues funcions sobre una mateixa entitat (cross-layer). L'esquema proposat té com a principal característica la seva baixa complexitat i que permet operar amb transmissions multimedia. Alhora, posteriors millores realitzades per l'autor sobre l'esquema proposat han permès també reduir els requeriments de senyalització i combinar de forma óptima usuaris d'alta i baixa mobilitat sobre el mateix accés ràdio, millorant encara més l'eficiència espectral del sistema. En cas d'enllaços amb múltiples antenes es proposa un nou esquema que combina la selecció del conjunt optim d'antenes transmissores amb la selecció de la codificació espai- (frequència-) temps. Finalment es donen una sèrie de recomanacions per tal de combinar totes dues línies d'investigació, així con un estat de l'art de les tècniques proposades per altres autors que combinen en part la gestió dels recursos ràdio i els esquemes de transmissió amb múltiples antenes.Uno de los aspectos claves en el diseño y gestión de las redes inalámbricas de banda ancha es el uso eficiente de los recursos radio. Desde el punto de vista del operador, el ancho de banda es un bien escaso y valioso que se debe explotar y gestionar de la forma más eficiente posible sin afectar a la calidad del servicio ofrecido. Por otro lado, desde el punto de vista del usuario, la calidad del servicio ha de ser comparable al ofrecido por las redes fijas, requiriendo así un bajo retardo y una baja tasa de perdida de paquetes para cada uno de los flujos de datos entre la red y el usuario. Durante los últimos años el número de técnicas y algoritmos que tratan de incrementar la eficiencia espectral en dichas redes es bastante amplio. Entre estas técnicas destaca el uso de múltiples antenas en el transmisor y en el receptor con el objetivo de poder transmitir simultáneamente diferentes flujos de datos sin necesidad de incrementar el ancho de banda. Por otro lado, la optimización conjunta de la capa de acceso al medio y la capa física (utilizando información de estado del canal para gestionar de manera óptima los recursos) también permite incrementar sensiblemente la eficiencia espectral del sistema.El objetivo de esta tesis es el estudio y desarrollo de nuevas técnicas de adaptación del enlace y la gestión de los recursos radio, y su posterior aplicación sobre los sistemas de acceso radio de próxima generación (Beyond 3G). Los estudios realizados parten de la premisa de que el transmisor conoce (parcialmente) el estado del canal a la vez que se considera que la transmisión se realiza sobre un sistema de transmisión multiportadora con múltiple antenas en el transmisor y el receptor. La tesis se centra sobre dos líneas de investigación, la primera para casos de una única antena en cada lado del enlace, y la segunda en caso de múltiples antenas en cada lado. Para el caso de una única antena en el transmisor y en el receptor, se ha desarrollado un nuevo esquema de asignación de los recursos radio así como de priorización de los paquetes de datos (scheduling) integrando ambas funciones sobre una misma entidad (cross-layer). El esquema propuesto tiene como principal característica su bajo coste computacional a la vez que se puede aplicar en caso de transmisiones multimedia. Posteriores mejoras realizadas por el autor sobre el esquema propuesto han permitido también reducir los requisitos de señalización así como combinar de forma óptima usuarios de alta y baja movilidad. Por otro lado, en caso de enlaces con múltiples antenas en transmisión y recepción, se presenta un nuevo esquema de adaptación en el cual se combina la selección de la(s) antena(s) transmisora(s) con la selección del esquema de codificación espacio-(frecuencia-) tiempo. Para finalizar, se dan una serie de recomendaciones con el objetivo de combinar ambas líneas de investigación, así como un estado del arte de las técnicas propuestas por otros autores que combinan en parte la gestión de los recursos radio y los esquemas de transmisión con múltiples antenas.In Broadband Wireless Access systems the efficient use of the resources is crucial from many points of views. From the operator point of view, the bandwidth is a scarce, valuable, and expensive resource which must be exploited in an efficient manner while the Quality of Service (QoS) provided to the users is guaranteed. On the other hand, a tight delay and link quality constraints are imposed on each data flow hence the user experiences the same quality as in fixed networks. During the last few years many techniques have been developed in order to increase the spectral efficiency and the throughput. Among them, the use of multiple antennas at the transmitter and the receiver (exploiting spatial multiplexing) with the joint optimization of the medium access control layer and the physical layer parameters.In this Ph.D. thesis, different adaptive techniques for B3G multicarrier wireless systems are developed and proposed focusing on the SS-MC-MA and the OFDM(A) (IEEE 802.16a/e/m standards) communication schemes. The research lines emphasize into the adaptation of the transmission having (Partial) knowledge of the Channel State Information for both; single antenna and multiple antenna links. For single antenna links, the implementation of a joint resource allocation and scheduling strategy by including adaptive modulation and coding is investigated. A low complexity resource allocation and scheduling algorithm is proposed with the objective to cope with real- and/or non-real- time requirements and constraints. A special attention is also devoted in reducing the required signalling. However, for multiple antenna links, the performance of a proposed adaptive transmit antenna selection scheme jointly with space-time block coding selection is investigated and compared with conventional structures. In this research line, mainly two optimizations criteria are proposed for spatial link adaptation, one based on the minimum error rate for fixed throughput, and the second focused on the maximisation of the rate for fixed error rate. Finally, some indications are given on how to include the spatial adaptation into the investigated and proposed resource allocation and scheduling process developed for single antenna transmission

Hybrid Solution of Stochastic Optimal Control Problems using Gauss Pseudospectral Method and Generalized Polynomial Chaos Algorithms

Two numerical methods, Gauss Pseudospectral Method and Generalized Polynomial Chaos Algorithm, were combined to form a hybrid algorithm for solving nonlinear optimal control and optimal path planning problems with uncertain parameters. The algorithm was applied to two concept demonstration problems: a nonlinear optimal control problem with multiplicative uncertain elements and a mission planning problem sponsored by USSTRATCOM. The mission planning scenario was constructed to find the path that minimizes the probability of being killed by lethal threats whose locations are uncertain to statistically quantify the effects those uncertainties have on the flight path solution, and to use the statistical properties to estimate the probability that the vehicle will be killed during mission execution. The results demonstrated that the method is able to effectively characterize how the optimal solution changes with uncertainty and that the results can be presented in a form that can be used by mission planners and aircrews to assess risks associated with a mission profile

The Value of Online Medication Rating Systems to Older Adults and Their Association with Self-Reported Outcomes

The Internet is a powerful and very popular vehicle for distributing judgment-free health information to patients. Multiple studies have examined the role of online health information as well as physician-rating websites in health care. Studies have examined the value of online drug information for patients and the value of the online drug information for patients. However, no study has examined the usefulness or value of online medication rating websites in facilitating physician-patient communication or participant-reported outcomes. In this study, the value of online medication rating websites to older adults in facilitating communication with their physicians using a newly developed tool was assessed. Additionally, the participant-reported outcomes of quality of life, satisfaction with physician communication, beliefs about medications, and medication adherence plus the relationship between the older adults’ actual ratings of their antihypertensive medications and their self-reported outcomes were examined. Older adults with poor quality of life were more likely to view the online medication rating websites more favorably than participants who enjoy good quality of life. Participants who liked to share health decisions with their physicians were also more likely to have favorable views of the online websites. In addition, older adults with hypertension, who highly rated their antihypertensive medication regimens, were more likely to have good physical quality of life, high satisfaction with physician communication, positive beliefs about medications, and high medication adherence. Older adults with poor quality of life were more likely to be unsatisfied with their antihypertensive medications, have multiple comorbidities, limited health literacy, low satisfaction with their communication with their physicians, take multiple medications, and were more likely to view online medication rating websites favorably compared to their counterparts with good quality of life. Online medication rating websites may play an important role in enhancing physician-patient communication particularly among this segment of the patient population

Mammography

In this volume, the topics are constructed from a variety of contents: the bases of mammography systems, optimization of screening mammography with reference to evidence-based research, new technologies of image acquisition and its surrounding systems, and case reports with reference to up-to-date multimodality images of breast cancer. Mammography has been lagged in the transition to digital imaging systems because of the necessity of high resolution for diagnosis. However, in the past ten years, technical improvement has resolved the difficulties and boosted new diagnostic systems. We hope that the reader will learn the essentials of mammography and will be forward-looking for the new technologies. We want to express our sincere gratitude and appreciation?to all the co-authors who have contributed their work to this volume

Current Challenges and Advances in Cataract Surgery

This reprint focuses on new trials related to cataract surgery, intraocular lens power calculations for cataracts after refractive surgery, problems related to high myopia, toric IOL power calculations, etc. Intraoperative use of the 3D Viewing System and OCT, studies on the spectacle dependence of EDOF, IOL fixation status and visual function, and dry eye after FLAC are also discussed. Proteomic analysis of aqueous humor proteins is also discussed