9,550 research outputs found
Report from the Tri-Agency Cosmological Simulation Task Force
The Tri-Agency Cosmological Simulations (TACS) Task Force was formed when
Program Managers from the Department of Energy (DOE), the National Aeronautics
and Space Administration (NASA), and the National Science Foundation (NSF)
expressed an interest in receiving input into the cosmological simulations
landscape related to the upcoming DOE/NSF Vera Rubin Observatory (Rubin),
NASA/ESA's Euclid, and NASA's Wide Field Infrared Survey Telescope (WFIRST).
The Co-Chairs of TACS, Katrin Heitmann and Alina Kiessling, invited community
scientists from the USA and Europe who are each subject matter experts and are
also members of one or more of the surveys to contribute. The following report
represents the input from TACS that was delivered to the Agencies in December
2018.Comment: 36 pages, 3 figures. Delivered to NASA, NSF, and DOE in Dec 201
An Overview on Application of Machine Learning Techniques in Optical Networks
Today's telecommunication networks have become sources of enormous amounts of
widely heterogeneous data. This information can be retrieved from network
traffic traces, network alarms, signal quality indicators, users' behavioral
data, etc. Advanced mathematical tools are required to extract meaningful
information from these data and take decisions pertaining to the proper
functioning of the networks from the network-generated data. Among these
mathematical tools, Machine Learning (ML) is regarded as one of the most
promising methodological approaches to perform network-data analysis and enable
automated network self-configuration and fault management. The adoption of ML
techniques in the field of optical communication networks is motivated by the
unprecedented growth of network complexity faced by optical networks in the
last few years. Such complexity increase is due to the introduction of a huge
number of adjustable and interdependent system parameters (e.g., routing
configurations, modulation format, symbol rate, coding schemes, etc.) that are
enabled by the usage of coherent transmission/reception technologies, advanced
digital signal processing and compensation of nonlinear effects in optical
fiber propagation. In this paper we provide an overview of the application of
ML to optical communications and networking. We classify and survey relevant
literature dealing with the topic, and we also provide an introductory tutorial
on ML for researchers and practitioners interested in this field. Although a
good number of research papers have recently appeared, the application of ML to
optical networks is still in its infancy: to stimulate further work in this
area, we conclude the paper proposing new possible research directions
Contextual Analysis of Large-Scale Biomedical Associations for the Elucidation and Prioritization of Genes and their Roles in Complex Disease
Vast amounts of biomedical associations are easily accessible in public resources, spanning gene-disease associations, tissue-specific gene expression, gene function and pathway annotations, and many other data types. Despite this mass of data, information most relevant to the study of a particular disease remains loosely coupled and difficult to incorporate into ongoing research. Current public databases are difficult to navigate and do not interoperate well due to the plethora of interfaces and varying biomedical concept identifiers used. Because no coherent display of data within a specific problem domain is available, finding the latent relationships associated with a disease of interest is impractical.
This research describes a method for extracting the contextual relationships embedded within associations relevant to a disease of interest. After applying the method to a small test data set, a large-scale integrated association network is constructed for application of a network propagation technique that helps uncover more distant latent relationships. Together these methods are adept at uncovering highly relevant relationships without any a priori knowledge of the disease of interest.
The combined contextual search and relevance methods power a tool which makes pertinent biomedical associations easier to find, easier to assimilate into ongoing work, and more prominent than currently available databases. Increasing the accessibility of current information is an important component to understanding high-throughput experimental results and surviving the data deluge
Update and Compensation of Radio Map Based on Statistical Inference
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Updates in metabolomics tools and resources: 2014-2015
Data processing and interpretation represent the most challenging and time-consuming steps in high-throughput metabolomic experiments, regardless of the analytical platforms (MS or NMR spectroscopy based) used for data acquisition. Improved machinery in metabolomics generates increasingly complex datasets that create the need for more and better processing and analysis software and in silico approaches to understand the resulting data. However, a comprehensive source of information describing the utility of the most recently developed and released metabolomics resourcesâin the form of tools, software, and databasesâis currently lacking. Thus, here we provide an overview of freely-available, and open-source, tools, algorithms, and frameworks to make both upcoming and established metabolomics researchers aware of the recent developments in an attempt to advance and facilitate data processing workflows in their metabolomics research. The major topics include tools and researches for data processing, data annotation, and data visualization in MS and NMR-based metabolomics. Most in this review described tools are dedicated to untargeted metabolomics workflows; however, some more specialist tools are described as well. All tools and resources described including their analytical and computational platform dependencies are summarized in an overview Table
Enabling Micro-level Demand-Side Grid Flexiblity in Resource Constrained Environments
The increased penetration of uncertain and variable renewable energy presents
various resource and operational electric grid challenges. Micro-level
(household and small commercial) demand-side grid flexibility could be a
cost-effective strategy to integrate high penetrations of wind and solar
energy, but literature and field deployments exploring the necessary
information and communication technologies (ICTs) are scant. This paper
presents an exploratory framework for enabling information driven grid
flexibility through the Internet of Things (IoT), and a proof-of-concept
wireless sensor gateway (FlexBox) to collect the necessary parameters for
adequately monitoring and actuating the micro-level demand-side. In the summer
of 2015, thirty sensor gateways were deployed in the city of Managua
(Nicaragua) to develop a baseline for a near future small-scale demand response
pilot implementation. FlexBox field data has begun shedding light on
relationships between ambient temperature and load energy consumption, load and
building envelope energy efficiency challenges, latency communication network
challenges, and opportunities to engage existing demand-side user behavioral
patterns. Information driven grid flexibility strategies present great
opportunity to develop new technologies, system architectures, and
implementation approaches that can easily scale across regions, incomes, and
levels of development
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