3,141 research outputs found

    Index to NASA tech briefs, 1971

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    The entries are listed by category, subject, author, originating source, source number/Tech Brief number, and Tech Brief number/source number. There are 528 entries

    NASA Tech Briefs Index, 1976

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    Abstracts of new technology derived from the research and development activities of the National Aeronautics and Space Administration are presented. Emphasis is placed on information considered likely to be transferrable across industrial, regional, or disciplinary lines. Subject matter covered includes: electronic components and circuits; electronic systems; physical sciences; materials; life sciences; mechanics; machinery; fabrication technology; and mathematics and information sciences

    Optofluidic plasmonic onchip nanosensor array for biodetection

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    Thesis (Ph.D.)--Boston UniversitySurface plasmon resonance (SPR) sensing has been demonstrated in the past decade to be the gold standard technique for biochemical interaction analysis, and plays an important role in drug discovery and biomedical research. The technique circumvents the need of fluorescence/radioactive tagging or enzymatic detection, enables ultrasensitive remote sensing, and quantitatively monitors bio-interaction in real time. Although SPR has these attractive features that can satisfy most research/clinic requirements, there still exist problems that limit its applications. First, the reflection geometry of the prism coupling scheme adds limitations for high throughput screening application. Additionally, SPR instrumentations are bulky and not suitable for point-of-care settings. Moreover, the SPR sensor is embedded in conventional micro-fluidic cells, in which the sensor performance is limited by inefficient analyte transport. Suspended plasmonic nanohole array (PNA) offers an opportunity to overcome these limitations. A collinear excitation/collection coupling scheme combined with the small footprint of PNA provides unique platform for multiplexing and system minimization. The suspended nanohole structure also offers a unique configuration to integrate nano-photonics with nano-fluidics. This thesis focuses on developing a lab-on-a-chip PNA platform for point-of-care bio-detection. To achieve this, we first demonstrate that the figure-of-merit of our PNA sensor surpasses that of the prism coupled SPR. We also show that the ultrasensitive label-free PNA sensor is able to directly detect intact viruses from biological media at clinically relevant concentrations with little sample preparation. We then present a plasmonic microarray with over one million PNA sensors on a microscope slide for high throughput screening applications. A dual-color filter imaging method is introduced to increase the accuracy, reliability, and signal-to-noise ratio in a highly multiplexed manner. Finally, we present a nanoplasmonic-nanofluidic platform enabling active delivery of analyte to the sensor. Sensor response time is reduced by an order of magnitude compared to the conventional flow scheme. A dynamic range spanning 5 orders of magnitude from 10^3 to 10^7 particles/mL is shown on this platform corresponding to analyte concentration sufficient for clinical applications. The proposed approach opens up opportunities of a lab-on-a-chip bio-detection system for drug screening, disease diagnostic as well as clinic studies

    Defect and thickness inspection system for cast thin films using machine vision and full-field transmission densitometry

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    Quick mass production of homogeneous thin film material is required in paper, plastic, fabric, and thin film industries. Due to the high feed rates and small thicknesses, machine vision and other nondestructive evaluation techniques are used to ensure consistent, defect-free material by continuously assessing post-production quality. One of the fastest growing inspection areas is for 0.5-500 micrometer thick thin films, which are used for semiconductor wafers, amorphous photovoltaics, optical films, plastics, and organic and inorganic membranes. As a demonstration application, a prototype roll-feed imaging system has been designed to inspect high-temperature polymer electrolyte membrane (PEM), used for fuel cells, after being die cast onto a moving transparent substrate. The inspection system continuously detects thin film defects and classifies them with a neural network into categories of holes, bubbles, thinning, and gels, with a 1.2% false alarm rate, 7.1% escape rate, and classification accuracy of 96.1%. In slot die casting processes, defect types are indicative of a misbalance in the mass flow rate and web speed; so, based on the classified defects, the inspection system informs the operator of corrective adjustments to these manufacturing parameters. Thickness uniformity is also critical to membrane functionality, so a real-time, full-field transmission densitometer has been created to measure the bi-directional thickness profile of the semi-transparent PEM between 25-400 micrometers. The local thickness of the 75 mm x 100 mm imaged area is determined by converting the optical density of the sample to thickness with the Beer-Lambert law. The PEM extinction coefficient is determined to be 1.4 D/mm and the average thickness error is found to be 4.7%. Finally, the defect inspection and thickness profilometry systems are compiled into a specially-designed graphical user interface for intuitive real-time operation and visualization.M.S.Committee Chair: Tequila Harris; Committee Member: Levent Degertekin; Committee Member: Wayne Dale

    Smart Sensor Technologies for IoT

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    The recent development in wireless networks and devices has led to novel services that will utilize wireless communication on a new level. Much effort and resources have been dedicated to establishing new communication networks that will support machine-to-machine communication and the Internet of Things (IoT). In these systems, various smart and sensory devices are deployed and connected, enabling large amounts of data to be streamed. Smart services represent new trends in mobile services, i.e., a completely new spectrum of context-aware, personalized, and intelligent services and applications. A variety of existing services utilize information about the position of the user or mobile device. The position of mobile devices is often achieved using the Global Navigation Satellite System (GNSS) chips that are integrated into all modern mobile devices (smartphones). However, GNSS is not always a reliable source of position estimates due to multipath propagation and signal blockage. Moreover, integrating GNSS chips into all devices might have a negative impact on the battery life of future IoT applications. Therefore, alternative solutions to position estimation should be investigated and implemented in IoT applications. This Special Issue, “Smart Sensor Technologies for IoT” aims to report on some of the recent research efforts on this increasingly important topic. The twelve accepted papers in this issue cover various aspects of Smart Sensor Technologies for IoT

    Human retinal oximetry using hyperspectral imaging

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    The aim of the work reported in this thesis was to investigate the possibility of measuring human retinal oxygen saturation using hyperspectral imaging. A direct non-invasive quantitative mapping of retinal oxygen saturation is enabled by hyperspectral imaging whereby the absorption spectra of oxygenated and deoxygenated haemoglobin are recorded and analysed. Implementation of spectral retinal imaging thus requires ophthalmic instrumentation capable of efficiently recording the requisite spectral data cube. For this purpose, a spectral retinal imager was developed for the first time by integrating a liquid crystal tuneable filter into the illumination system of a conventional fundus camera to enable the recording of narrow-band spectral images in time sequence from 400nm to 700nm. Postprocessing algorithms were developed to enable accurate exploitation of spectral retinal images and overcome the confounding problems associated with this technique due to the erratic eye motion and illumination variation. Several algorithms were developed to provide semi-quantitative and quantitative oxygen saturation measurements. Accurate quantitative measurements necessitated an optical model of light propagation into the retina that takes into account the absorption and scattering of light by red blood cells. To validate the oxygen saturation measurements and algorithms, a model eye was constructed and measurements were compared with gold-standard measurements obtained by a Co-Oximeter. The accuracy of the oxygen saturation measurements was (3.31%± 2.19) for oxygenated blood samples. Clinical trials from healthy and diseased subjects were analysed and oxygen saturation measurements were compared to establish a merit of certain retinal diseases. Oxygen saturation measurements were in agreement with clinician expectations in both veins (48%±9) and arteries (96%±5). We also present in this thesis the development of novel clinical instrument based on IRIS to perform retinal oximetry.Al-baath University, Syri

    Detection of Surface Cracks in Metals using Microwave and Millimeter-Wave Nondestructive Testing Techniques-A Review

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    Integrity Assessment of Metallic Structures Requires Inspection Tools Capable of Detecting and Evaluating Cracks Reliably. to This End, Many Microwave and Millimeter-Wave Nondestructive Testing and Evaluation (NDT&E) Methods Have Been Developed and Applied Successfully in the Past. Detection of Fatigue Cracks with Widths Less Than 5 Μ M using Noncontact Microwave-Based Inspection Methods Was Demonstrated in the 1970s. Since their Introduction, These Methods Have Evolved Considerably Toward Enhancing the Detection Sensitivity and Resolution. Undertaking Key Application Challenges Has Attracted Considerable Attention in the Past Three Decades and Led to the Development of the Near-Field Techniques for Crack Detection. to Address a Need that Cannot Be Fulfilled by Other NDT&E Modalities, Innovative Noncontact Microwave and Millimeter-Wave NDT&E Methods Were Devised Recently to Detect Cracks of Arbitrary Orientations under Thick Dielectric Structures. While the Reported Methods Share the Same Underlying Physical Principles, They Vary Considerably in Terms of the Devised Probes/sensors and the Application Procedure. Consequently, their Sensitivity and Resolution as Well as their Limitations Vary. This Article Reviews the Various Crack Detection Methods Developed To-Date and Compares Them in Terms of Common Performance Metrics. This Comprehensive Review is Augmented with Experimental Comparisons and Benchmarking Aimed to Benefit NDT&E Practitioners and Researchers Alike
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