Intraoperative detection of blood vessels with an imaging needle during neurosurgery in humans

Intracranial hemorrhage can be a devastating complication associated with needle biopsies of the brain. Hemorrhage can occur to vessels located adjacent to the biopsy needle as tissue is aspirated into the needle and removed. No intraoperative technology exists to reliably identify blood vessels that are at risk of damage. To address this problem, we developed an “imaging needle” that can visualize nearby blood vessels in real time. The imaging needle contains a miniaturized optical coherence tomography probe that allows differentiation of blood flow and tissue. In 11 patients, we were able to intraoperatively detect blood vessels (diameter, \u3e500 μm) with a sensitivity of 91.2% and a specificity of 97.7%. This is the first reported use of an optical coherence tomography needle probe in human brain in vivo. These results suggest that imaging needles may serve as a valuable tool in a range of neurosurgical needle interventions

Project Reach: Implementation of Evidence-Based Psychotherapy Within Integrated Healthcare for Hurricane Harvey Affected Individuals

Project Reach was established to deliver evidence-based mental healthcare services to children and adults affected by Hurricane Harvey and its aftermath. Through Project Reach, an innovative multi-component assessment and treatment service is utilized to identify and treat in integrated healthcare settings both children and adults exhibiting significant behavioral health concerns in Houston. The aim is to provide sustainable, integrated mental health services through primary care and school-based settings to post-Harvey affected individuals whose emotional needs remain unmet. This paper describes the design and implementation of Project Reach as well as special considerations for implementation. The overall goal of Project Reach is to form a platform for expanding integrated services for those affected by Harvey that will maximize behavioral health outcomes while reducing cost and improving access

The Importance Of Community: Investing In Effective Community-Based Crime Prevention Strategies

After more than a year of listening to our community, researching evidence-based practices, and evaluating our own efforts, 'The Importance of Community' inaugural report unequivocally asserts that our greatest potential of reducing homicides and incarceration as a result of committing a crime is deeply rooted in collective community action and targeted interventions aimed at serving narrowly defined populations. In this report, The Indianapolis Foundation will summarize years of community-based recommendations and provides a specific community investment plan based on multiple community convenings, crime prevention related reports, and listening to our community

Laser induced surface acoustic wave combined with phase sensitive optical coherence tomography for superficial tissue characterization:a solution for practical application

Mechanical properties are important parameters that can be used to assess the physiologic conditions of biologic tissue. Measurements and mapping of tissue mechanical properties can aid in the diagnosis, characterisation and treatment of diseases. As a non-invasive, non-destructive and non-contact method, laser induced surface acoustic waves (SAWs) have potential to accurately characterise tissue elastic properties. However, challenge still exists when the laser is directly applied to the tissue because of potential heat generation due to laser energy deposition. This paper focuses on the thermal effect of the laser induced SAW on the tissue target and provides an alternate solution to facilitate its application in clinic environment. The solution proposed is to apply a thin agar membrane as surface shield to protect the tissue. Transient thermal analysis is developed and verified by experiments to study the effects of the high energy Nd:YAG laser pulse on the surface shield. The approach is then verified by measuring the mechanical property of skin in a Thiel mouse model. The results demonstrate a useful step toward the practical application of laser induced SAW method for measuring real elasticity of normal and diseased tissues in dermatology and other surface epithelia

Anti-Poverty Strategies for the UK: Poverty and Crime Review

This review of the literature about how and why poverty and crime influence one another, and the benefits to crime reduction of reducing poverty, looks at the implications for practical policies and strategies

The Courage to Lead: The Leadership Legacies of American Presidents John Fitzgerald Kennedy and Theodore Roosevelt

Prolific writer Iodice chronicles the legacies of former American presidents John F. Kennedy and Theodore Roosevelt whose accomplishments, both domestic and international, shaped constituencies then and now. From the Panama Canal ― which opened up trade routes for global commerce — to the preservation of lands for environmental purposes and public enjoyment, to the enactment of civil rights legislation that would collectively create a template for future world leaders, Iodice emphasizes that these specific political icons blazed indelible trails