JPEG2000 ROI coding through component priority for digital mammography

Region Of Interest (ROI) coding is a prominent feature of some image coding systems aimed to prioritize specific areas of the image through the construction of a codestream that, decoded at increasing bit-rates, recovers the ROI first and with higher quality than the rest of the image. JPEG2000 is a wavelet-based coding system that is supported in the Digital Imaging and Communications in Medicine (DICOM) standard. Among other features, JPEG2000 provides lossy-to-lossless compression and ROI coding, which are especially relevant to the medical community. But, due to JPEG2000 supported ROI coding methods that guarantee lossless coding are not designed to achieve a high degree of accuracy to prioritize ROIs, they have not been incorporated in the medical community. - This paper introduces a ROI coding method that is able to prioritize multiple ROIs at different priorities, guaranteeing lossy-to-lossless coding. The proposed ROI Coding Through Component Prioritization (ROITCOP) method uses techniques of rate-distortion optimization combined with a simple yet effective strategy of ROI allocation that employs the multi-component support of JPEG2000 codestream. The main insight in ROITCOP is the allocation of each ROI to an component. Experimental results indicate that this ROI allocation strategy does not penalize coding performance whilst achieving an unprecedented degree of accuracy to delimit ROIs. - The proposed ROITCOP method maintains JPEG2000 compliance, thus easing its use in medical centers to share images. This paper analyzes in detail the use of ROITCOP to mammographies, where the ROIs are identified by computer-aided diagnosis. Extensive experimental tests using various ROI coding methods suggest that ROITCOP achieves enhanced coding performanc

JPEG2000 ROI coding through component priority for digital mammography

Region Of Interest (ROI) coding is a prominent feature of some image coding systems aimed to prioritize specific areas of the image through the construction of a codestream that, decoded at increasing bit-rates, recovers the ROI first and with higher quality than the rest of the image. JPEG2000 is a wavelet-based coding system that is supported in the Digital Imaging and Communications in Medicine (DICOM) standard. Among other features, JPEG2000 provides lossy-to-lossless compression and ROI coding, which are especially relevant to the medical community. But, due to JPEG2000 supported ROI coding methods that guarantee lossless coding are not designed to achieve a high degree of accuracy to prioritize ROIs, they have not been incorporated in the medical community. - This paper introduces a ROI coding method that is able to prioritize multiple ROIs at different priorities, guaranteeing lossy-to-lossless coding. The proposed ROI Coding Through Component Prioritization (ROITCOP) method uses techniques of rate-distortion optimization combined with a simple yet effective strategy of ROI allocation that employs the multi-component support of JPEG2000 codestream. The main insight in ROITCOP is the allocation of each ROI to an component. Experimental results indicate that this ROI allocation strategy does not penalize coding performance whilst achieving an unprecedented degree of accuracy to delimit ROIs. - The proposed ROITCOP method maintains JPEG2000 compliance, thus easing its use in medical centers to share images. This paper analyzes in detail the use of ROITCOP to mammographies, where the ROIs are identified by computer-aided diagnosis. Extensive experimental tests using various ROI coding methods suggest that ROITCOP achieves enhanced coding performanc

Hybrid Region-based Image Compression Scheme for Mamograms and Ultrasound Images

The need for transmission and archive of mammograms and ultrasound Images has dramatically increased in tele-healthcare applications. Such images require large amount of' storage space which affect transmission speed. Therefore an effective compression scheme is essential. Compression of these images. in general. laces a great challenge to compromise between the higher compression ratio and the relevant diagnostic information. Out of the many studied compression schemes. lossless . IPl. (i- LS and lossy SPII IT are found to he the most efficient ones. JPEG-LS and SI'll IT are chosen based on a comprehensive experimental study carried on a large number of mammograms and ultrasound images of different sizes and texture. The lossless schemes are evaluated based on the compression ratio and compression speed. The distortion in the image quality which is introduced by lossy methods evaluated based on objective criteria using Mean Square Error (MSE) and Peak signal to Noise Ratio (PSNR). It is found that lossless compression can achieve a modest compression ratio 2: 1 - 4: 1. bossy compression schemes can achieve higher compression ratios than lossless ones but at the price of the image quality which may impede diagnostic conclusions. In this work, a new compression approach called Ilvbrid Region-based Image Compression Scheme (IIYRICS) has been proposed for the mammograms and ultrasound images to achieve higher compression ratios without compromising the diagnostic quality. In I LYRICS, a modification for JPI; G-LS is introduced to encode the arbitrary shaped disease affected regions. Then Shape adaptive SPIT IT is applied on the remaining non region of interest. The results clearly show that this hybrid strategy can yield high compression ratios with perfect reconstruction of diagnostic relevant regions, achieving high speed transmission and less storage requirement. For the sample images considered in our experiment, the compression ratio increases approximately ten times. However, this increase depends upon the size of the region of interest chosen. It is also föund that the pre-processing (contrast stretching) of region of interest improves compression ratios on mammograms but not on ultrasound images

Correlation modeling for compression of computed tomography images

Abstract-Computed Tomography (CT) is a noninvasive medical test obtained via a series of X-ray exposures resulting in 3D images that aid medical diagnosis. Previous approaches for coding such 3D images propose to employ multi-component transforms to exploit correlation among CT slices, but these approaches do not always improve coding performance with respect to a simpler slice-by-slice coding approach. In this work, we propose a novel analysis which accurately predicts when the use of a multi-component transform is profitable. This analysis models the correlation coefficient r based on image acquisition parameters readily available at acquisition time. Extensive experimental results from multiple image sensors suggest that multi-component transforms are appropriate for images with correlation coefficient r in excess of 0.87

Hybrid Region-based Image Compression Scheme for Mamograms and Ultrasound Images

The need for transmission and archive of mammograms and ultrasound Images has dramatically increased in tele-healthcare applications. Such images require large amount of' storage space which affect transmission speed. Therefore an effective compression scheme is essential. Compression of these images. in general. laces a great challenge to compromise between the higher compression ratio and the relevant diagnostic information. Out of the many studied compression schemes. lossless . IPl. (i- LS and lossy SPII IT are found to he the most efficient ones. JPEG-LS and SI'll IT are chosen based on a comprehensive experimental study carried on a large number of mammograms and ultrasound images of different sizes and texture. The lossless schemes are evaluated based on the compression ratio and compression speed. The distortion in the image quality which is introduced by lossy methods evaluated based on objective criteria using Mean Square Error (MSE) and Peak signal to Noise Ratio (PSNR). It is found that lossless compression can achieve a modest compression ratio 2: 1 - 4: 1. bossy compression schemes can achieve higher compression ratios than lossless ones but at the price of the image quality which may impede diagnostic conclusions. In this work, a new compression approach called Ilvbrid Region-based Image Compression Scheme (IIYRICS) has been proposed for the mammograms and ultrasound images to achieve higher compression ratios without compromising the diagnostic quality. In I LYRICS, a modification for JPI; G-LS is introduced to encode the arbitrary shaped disease affected regions. Then Shape adaptive SPIT IT is applied on the remaining non region of interest. The results clearly show that this hybrid strategy can yield high compression ratios with perfect reconstruction of diagnostic relevant regions, achieving high speed transmission and less storage requirement. For the sample images considered in our experiment, the compression ratio increases approximately ten times. However, this increase depends upon the size of the region of interest chosen. It is also föund that the pre-processing (contrast stretching) of region of interest improves compression ratios on mammograms but not on ultrasound images

Efficient storage of microCT data preserving bone morphometry assessment

Available online 15 July 2015Preclinical micro-computed tomography (microCT) images are of utility for 3D morphological bone evaluation, which is of great interest in cancer detection and treatment development. This work introduces a compression strategy for microCTs that allocates specific substances in different Volumes of Interest (VoIs). The allocation procedure is conducted by the Hounsfield scale. The VoIs are coded independently and then grouped in a single DICOM-compliant file. The proposed method permits the use of different codecs, identifies and transmit data corresponding to a particular substance in the compressed domain without decoding the volume(s), and allows the computation of the 3D morphometry without needing to store or transmit the whole image. The proposed approach reduces the transmitted data in more than 90% when the 3D morphometry evaluation is performed in high density and low density bone. This work can be easily extended to other imaging modalities and applications that work with the Hounsfield scale

2-step scalar deadzone quantization for bitplane image coding

Modern lossy image coding systems generate a quality progressive codestream that, truncated at increasing rates, produces an image with decreasing distortion. Quality progressivity is commonly provided by an embedded quantizer that employs uniform scalar deadzone quantization (USDQ) together with a bitplane coding strategy. This paper introduces a 2-step scalar deadzone quantization (2SDQ) scheme that achieves same coding performance as that of USDQ while reducing the coding passes and the emitted symbols of the bitplane coding engine. This serves to reduce the computational costs of the codec and/or to code high dynamic range images. The main insights behind 2SDQ are the use of two quantization step sizes that approximate wavelet coefficients with more or less precision depending on their density, and a rate-distortion optimization technique that adjusts the distortion decreases produced when coding 2SDQ indexes. The integration of 2SDQ in current codecs is straightforward. The applicability and efficiency of 2SDQ are demonstrated within the framework of JPEG2000

Design of a secure architecture for the exchange of biomedical information in m-Health scenarios

El paradigma de m-Salud (salud móvil) aboga por la integración masiva de las más avanzadas tecnologías de comunicación, red móvil y sensores en aplicaciones y sistemas de salud, para fomentar el despliegue de un nuevo modelo de atención clínica centrada en el usuario/paciente. Este modelo tiene por objetivos el empoderamiento de los usuarios en la gestión de su propia salud (p.ej. aumentando sus conocimientos, promocionando estilos de vida saludable y previniendo enfermedades), la prestación de una mejor tele-asistencia sanitaria en el hogar para ancianos y pacientes crónicos y una notable disminución del gasto de los Sistemas de Salud gracias a la reducción del número y la duración de las hospitalizaciones. No obstante, estas ventajas, atribuidas a las aplicaciones de m-Salud, suelen venir acompañadas del requisito de un alto grado de disponibilidad de la información biomédica de sus usuarios para garantizar una alta calidad de servicio, p.ej. fusionar varias señales de un usuario para obtener un diagnóstico más preciso. La consecuencia negativa de cumplir esta demanda es el aumento directo de las superficies potencialmente vulnerables a ataques, lo que sitúa a la seguridad (y a la privacidad) del modelo de m-Salud como factor crítico para su éxito. Como requisito no funcional de las aplicaciones de m-Salud, la seguridad ha recibido menos atención que otros requisitos técnicos que eran más urgentes en etapas de desarrollo previas, tales como la robustez, la eficiencia, la interoperabilidad o la usabilidad. Otro factor importante que ha contribuido a retrasar la implementación de políticas de seguridad sólidas es que garantizar un determinado nivel de seguridad implica unos costes que pueden ser muy relevantes en varias dimensiones, en especial en la económica (p.ej. sobrecostes por la inclusión de hardware extra para la autenticación de usuarios), en el rendimiento (p.ej. reducción de la eficiencia y de la interoperabilidad debido a la integración de elementos de seguridad) y en la usabilidad (p.ej. configuración más complicada de dispositivos y aplicaciones de salud debido a las nuevas opciones de seguridad). Por tanto, las soluciones de seguridad que persigan satisfacer a todos los actores del contexto de m-Salud (usuarios, pacientes, personal médico, personal técnico, legisladores, fabricantes de dispositivos y equipos, etc.) deben ser robustas y al mismo tiempo minimizar sus costes asociados. Esta Tesis detalla una propuesta de seguridad, compuesta por cuatro grandes bloques interconectados, para dotar de seguridad a las arquitecturas de m-Salud con unos costes reducidos. El primer bloque define un esquema global que proporciona unos niveles de seguridad e interoperabilidad acordes con las características de las distintas aplicaciones de m-Salud. Este esquema está compuesto por tres capas diferenciadas, diseñadas a la medidas de los dominios de m-Salud y de sus restricciones, incluyendo medidas de seguridad adecuadas para la defensa contra las amenazas asociadas a sus aplicaciones de m-Salud. El segundo bloque establece la extensión de seguridad de aquellos protocolos estándar que permiten la adquisición, el intercambio y/o la administración de información biomédica -- por tanto, usados por muchas aplicaciones de m-Salud -- pero no reúnen los niveles de seguridad detallados en el esquema previo. Estas extensiones se concretan para los estándares biomédicos ISO/IEEE 11073 PHD y SCP-ECG. El tercer bloque propone nuevas formas de fortalecer la seguridad de los tests biomédicos, que constituyen el elemento esencial de muchas aplicaciones de m-Salud de carácter clínico, mediante codificaciones novedosas. Finalmente el cuarto bloque, que se sitúa en paralelo a los anteriores, selecciona herramientas genéricas de seguridad (elementos de autenticación y criptográficos) cuya integración en los otros bloques resulta idónea, y desarrolla nuevas herramientas de seguridad, basadas en señal -- embedding y keytagging --, para reforzar la protección de los test biomédicos.The paradigm of m-Health (mobile health) advocates for the massive integration of advanced mobile communications, network and sensor technologies in healthcare applications and systems to foster the deployment of a new, user/patient-centered healthcare model enabling the empowerment of users in the management of their health (e.g. by increasing their health literacy, promoting healthy lifestyles and the prevention of diseases), a better home-based healthcare delivery for elderly and chronic patients and important savings for healthcare systems due to the reduction of hospitalizations in number and duration. It is a fact that many m-Health applications demand high availability of biomedical information from their users (for further accurate analysis, e.g. by fusion of various signals) to guarantee high quality of service, which on the other hand entails increasing the potential surfaces for attacks. Therefore, it is not surprising that security (and privacy) is commonly included among the most important barriers for the success of m-Health. As a non-functional requirement for m-Health applications, security has received less attention than other technical issues that were more pressing at earlier development stages, such as reliability, eficiency, interoperability or usability. Another fact that has contributed to delaying the enforcement of robust security policies is that guaranteeing a certain security level implies costs that can be very relevant and that span along diferent dimensions. These include budgeting (e.g. the demand of extra hardware for user authentication), performance (e.g. lower eficiency and interoperability due to the addition of security elements) and usability (e.g. cumbersome configuration of devices and applications due to security options). Therefore, security solutions that aim to satisfy all the stakeholders in the m-Health context (users/patients, medical staff, technical staff, systems and devices manufacturers, regulators, etc.) shall be robust and, at the same time, minimize their associated costs. This Thesis details a proposal, composed of four interrelated blocks, to integrate appropriate levels of security in m-Health architectures in a cost-efcient manner. The first block designes a global scheme that provides different security and interoperability levels accordingto how critical are the m-Health applications to be implemented. This consists ofthree layers tailored to the m-Health domains and their constraints, whose security countermeasures defend against the threats of their associated m-Health applications. Next, the second block addresses the security extension of those standard protocols that enable the acquisition, exchange and/or management of biomedical information | thus, used by many m-Health applications | but do not meet the security levels described in the former scheme. These extensions are materialized for the biomedical standards ISO/IEEE 11073 PHD and SCP-ECG. Then, the third block proposes new ways of enhancing the security of biomedical standards, which are the centerpiece of many clinical m-Health applications, by means of novel codings. Finally the fourth block, with is parallel to the others, selects generic security methods (for user authentication and cryptographic protection) whose integration in the other blocks results optimal, and also develops novel signal-based methods (embedding and keytagging) for strengthening the security of biomedical tests. The layer-based extensions of the standards ISO/IEEE 11073 PHD and SCP-ECG can be considered as robust, cost-eficient and respectful with their original features and contents. The former adds no attributes to its data information model, four new frames to the service model |and extends four with new sub-frames|, and only one new sub-state to the communication model. Furthermore, a lightweight architecture consisting of a personal health device mounting a 9 MHz processor and an aggregator mounting a 1 GHz processor is enough to transmit a 3-lead electrocardiogram in real-time implementing the top security layer. The extra requirements associated to this extension are an initial configuration of the health device and the aggregator, tokens for identification/authentication of users if these devices are to be shared and the implementation of certain IHE profiles in the aggregator to enable the integration of measurements in healthcare systems. As regards to the extension of SCP-ECG, it only adds a new section with selected security elements and syntax in order to protect the rest of file contents and provide proper role-based access control. The overhead introduced in the protected SCP-ECG is typically 2{13 % of the regular file size, and the extra delays to protect a newly generated SCP-ECG file and to access it for interpretation are respectively a 2{10 % and a 5 % of the regular delays. As regards to the signal-based security techniques developed, the embedding method is the basis for the proposal of a generic coding for tests composed of biomedical signals, periodic measurements and contextual information. This has been adjusted and evaluated with electrocardiogram and electroencephalogram-based tests, proving the objective clinical quality of the coded tests, the capacity of the coding-access system to operate in real-time (overall delays of 2 s for electrocardiograms and 3.3 s for electroencephalograms) and its high usability. Despite of the embedding of security and metadata to enable m-Health services, the compression ratios obtained by this coding range from ' 3 in real-time transmission to ' 5 in offline operation. Complementarily, keytagging permits associating information to images (and other signals) by means of keys in a secure and non-distorting fashion, which has been availed to implement security measures such as image authentication, integrity control and location of tampered areas, private captioning with role-based access control, traceability and copyright protection. The tests conducted indicate a remarkable robustness-capacity tradeoff that permits implementing all this measures simultaneously, and the compatibility of keytagging with JPEG2000 compression, maintaining this tradeoff while setting the overall keytagging delay in only ' 120 ms for any image size | evidencing the scalability of this technique. As a general conclusion, it has been demonstrated and illustrated with examples that there are various, complementary and structured manners to contribute in the implementation of suitable security levels for m-Health architectures with a moderate cost in budget, performance, interoperability and usability. The m-Health landscape is evolving permanently along all their dimensions, and this Thesis aims to do so with its security. Furthermore, the lessons learned herein may offer further guidance for the elaboration of more comprehensive and updated security schemes, for the extension of other biomedical standards featuring low emphasis on security or privacy, and for the improvement of the state of the art regarding signal-based protection methods and applications

Understanding and advancing PDE-based image compression

This thesis is dedicated to image compression with partial differential equations (PDEs). PDE-based codecs store only a small amount of image points and propagate their information into the unknown image areas during the decompression step. For certain classes of images, PDE-based compression can already outperform the current quasi-standard, JPEG2000. However, the reasons for this success are not yet fully understood, and PDE-based compression is still in a proof-of-concept stage. With a probabilistic justification for anisotropic diffusion, we contribute to a deeper insight into design principles for PDE-based codecs. Moreover, by analysing the interaction between efficient storage methods and image reconstruction with diffusion, we can rank PDEs according to their practical value in compression. Based on these observations, we advance PDE-based compression towards practical viability: First, we present a new hybrid codec that combines PDE- and patch-based interpolation to deal with highly textured images. Furthermore, a new video player demonstrates the real-time capacities of PDE-based image interpolation and a new region of interest coding algorithm represents important image areas with high accuracy. Finally, we propose a new framework for diffusion-based image colourisation that we use to build an efficient codec for colour images. Experiments on real world image databases show that our new method is qualitatively competitive to current state-of-the-art codecs.Diese Dissertation ist der Bildkompression mit partiellen Differentialgleichungen (PDEs, partial differential equations) gewidmet. PDE-Codecs speichern nur einen geringen Anteil aller Bildpunkte und transportieren deren Information in fehlende Bildregionen. In einigen Fällen kann PDE-basierte Kompression den aktuellen Quasi-Standard, JPEG2000, bereits schlagen. Allerdings sind die Gründe für diesen Erfolg noch nicht vollständig erforscht, und PDE-basierte Kompression befindet sich derzeit noch im Anfangsstadium. Wir tragen durch eine probabilistische Rechtfertigung anisotroper Diffusion zu einem tieferen Verständnis PDE-basierten Codec-Designs bei. Eine Analyse der Interaktion zwischen effizienten Speicherverfahren und Bildrekonstruktion erlaubt es uns, PDEs nach ihrem Nutzen für die Kompression zu beurteilen. Anhand dieser Einsichten entwickeln wir PDE-basierte Kompression hinsichtlich ihrer praktischen Nutzbarkeit weiter: Wir stellen einen Hybrid-Codec für hochtexturierte Bilder vor, der umgebungsbasierte Interpolation mit PDEs kombiniert. Ein neuer Video-Dekodierer demonstriert die Echtzeitfähigkeit PDE-basierter Interpolation und eine Region-of-Interest-Methode erlaubt es, wichtige Bildbereiche mit hoher Genauigkeit zu speichern. Schlussendlich stellen wir ein neues diffusionsbasiertes Kolorierungsverfahren vor, welches uns effiziente Kompression von Farbbildern ermöglicht. Experimente auf Realwelt-Bilddatenbanken zeigen die Konkurrenzfähigkeit dieses Verfahrens auf