Aerospace Medicine and Biology: A continuing bibliography with indexes (supplement 314)

This bibliography lists 139 reports, articles, and other documents introduced into the NASA scientific and technical information system in August, 1988

Museum Lighting - an holistic approach

Among the environmental parameters that effect exhibited artifacts, light is the most complex and the only essential for the observer as to appreciate the artifacts, thus being one of the most critical variables of art exposure. Research on strategies for energy saving and the renovation of light destined to Heritage is examined by daylight admission and Light-Emitting Diode (LED) technology. The extended review of the literature presented below, over museum lighting, evidenced the parallel advance of lighting principles with lighting design, concerning what determines visual quality and perception. Lighting quality is an interdisciplinaryfield of research affecting human activity and under a requested task, visual performance, while at the same time improving well-being. In this sense, the role of the lighting designer is to match and rank human needs with economic and environmental aspects as to architectural principles and to translate the results into a feasible design and an efficient installation. Quality factors for art exposure, involving color fidelity and damage, along with visual perception necessitate of useful metrics through established criteria. The challenge for the museum for a holistic design of natural and artificial light is still missing of substantial metrics, even though recent findings provide some insight on the workflow to establish. Luminance-based design metrics and contrast criteria are used in this study as key strategies for museum lighting, combining comfort and viewing fine arts through advanced computer rendering. The exploration of the transition inside a daylit gallery where moving in the museum environment offers an experience for a series of adaptation changes through photopic, mesopic and dark-adapted scotopic function, along with change on the sensitivity of the spectrum. The luminance appearance and the transition adaptation in the museum field lack of research examination; the relationship of prescriptive requirements and luminance- based design has been explored initially in the field of road lighting, where the relative visual performance has been evidenced to be in the center of the CIE standard for tunnel lighting. Daylight simulation via climate-based modeling, introducing daylight filters as solar shading devices, has been proposed as the object of experimental research, connecting light “filtering” with luminance; this workflow could be applied in several fields of research considering museum environment and give responses in the preservation of artwork involving daylight. The subject of this thesis is the proposal of a ‘trama’ surface installed on windows to reduce and control daylight, studying how energy and conservation targets can be achieved. New light sources and smart control systems will integrate to a holistic approach for museum lighting design

Patient-specific planning for thermal magnetic resonance of glioblastoma multiforme

Thermal intervention is a potent sensitizer of cells to chemo- and radiotherapy in cancer treatment. Glioblastoma multiforme (GBM) is a potential clinical target, given the cancer's aggressive nature and resistance to current treatment options. This drives research into optimization algorithms for treatment planning as well as radiofrequency (RF) applicator design for treatment delivery. In this work, nine clinically realistic GBM target volumes (TVs) for thermal intervention are compared using three optimization algorithms and up to ten RF applicator designs for thermal magnetic resonance. Hyperthermia treatment planning (HTP) was successfully performed for all cases, including very small, large, and even split target volumes. Minimum requirements formulated for the metrics assessing HTP outcome were met and exceeded for all patient specific cases. Results indicate a 16 channel two row arrangement to be most promising. HTP of TVs with a small extent in the cranial–caudal direction in conjunction with a large radial extent remains challenging despite the advanced optimization algorithms used. In general, deep seated targets are favorable. Overall, our findings indicate that a one-size-fits-all RF applicator might not be the ultimate approach in hyperthermia of brain tumors. It stands to reason that modular and reconfigurable RF applicator configurations might best suit the needs of targeting individual GBM geometry

Optimising Light Source Spectrum to Reduce the Energy Absorbed by Objects

Light is used to illuminate objects in the built environment. Humans can only observe light reflected from an object. Light absorbed by an object turns into heat and does not contribute to visibility. Since the spectral output of the new lighting technologies can be tuned, it is possible to imagine a lighting system that detects the colours of objects and emits customised light to minimise the absorbed energy. Previous optimisation studies investigated the use of narrowband LEDs to maximise the efficiency and colour quality of a light source. While these studies aimed to tune a white light source for general use, the lighting system proposed here minimises the energy consumed by lighting by detecting colours of objects and emitting customised light onto each coloured part of the object. This thesis investigates the feasibility of absorption-minimising light source spectra and their impact on the colour appearance of objects and energy consumption. Two computational studies were undertaken to form the theoretical basis of the absorption-minimising light source spectra. Computational simulations show that the theoretical single-peak spectra can lower the energy consumption up to around 38 % to 62 %, and double-peak test spectra can result in energy savings up to 71 %, without causing colour shifts. In these studies, standard reference illuminants, theoretical test spectra and coloured test samples were used. These studies are followed by the empirical evidence collected from two psychophysical experiments. Data from the experiments show that observers find the colour appearance of objects equally natural and attractive under spectrally optimised spectra and reference white light sources. An increased colour difference, to a certain extent, is found acceptable, which allows even higher energy savings. However, the translucent nature of some objects may negatively affect the results