Certainty of outlier and boundary points processing in data mining

Data certainty is one of the issues in the real-world applications which is caused by unwanted noise in data. Recently, more attentions have been paid to overcome this problem. We proposed a new method based on neutrosophic set (NS) theory to detect boundary and outlier points as challenging points in clustering methods. Generally, firstly, a certainty value is assigned to data points based on the proposed definition in NS. Then, certainty set is presented for the proposed cost function in NS domain by considering a set of main clusters and noise cluster. After that, the proposed cost function is minimized by gradient descent method. Data points are clustered based on their membership degrees. Outlier points are assigned to noise cluster and boundary points are assigned to main clusters with almost same membership degrees. To show the effectiveness of the proposed method, two types of datasets including 3 datasets in Scatter type and 4 datasets in UCI type are used. Results demonstrate that the proposed cost function handles boundary and outlier points with more accurate membership degrees and outperforms existing state of the art clustering methods.Comment: Conference Paper, 6 page

Supporting Skin Lesion Diagnosis with Content-Based Image Retrieval

In recent years, many attempts have been dedicated to the creation of automated devices that could assist both expert and beginner dermatologists towards fast and early diagnosis of skin lesions. Tasks such as skin lesion classification and segmentation have been extensively addressed with deep learning algorithms, which in some cases reach a diagnostic accuracy comparable to that of expert physicians. However, the general lack of interpretability and reliability severely hinders the ability of those approaches to actually support dermatologists in the diagnosis process. In this paper a novel skin image retrieval system is presented, which exploits features extracted by Convolutional Neural Networks to gather similar images from a publicly available dataset, in order to assist the diagnosis process of both expert and novice practitioners. In the proposed framework, ResNet-50 is initially trained for the classification of dermoscopic images; then, the feature extraction part is isolated, and an embedding network is built on top of it. The embedding learns an alternative representation, which allows to check image similarity by means of a distance measure. Experimental results reveal that the proposed method is able to select meaningful images, which can effectively boost the classification accuracy of human dermatologists

Advancements and Breakthroughs in Ultrasound Imaging

Ultrasonic imaging is a powerful diagnostic tool available to medical practitioners, engineers and researchers today. Due to the relative safety, and the non-invasive nature, ultrasonic imaging has become one of the most rapidly advancing technologies. These rapid advances are directly related to the parallel advancements in electronics, computing, and transducer technology together with sophisticated signal processing techniques. This book focuses on state of the art developments in ultrasonic imaging applications and underlying technologies presented by leading practitioners and researchers from many parts of the world

Semantic Segmentation of Human Model Using Heat Kernel and Geodesic Distance

A novel approach of 3D human model segmentation is proposed, which is based on heat kernel signature and geodesic distance. Through calculating the heat kernel signature of the point clouds of human body model, the local maxima of thermal energy distribution of the model is found, and the set of feature points of the model is obtained. Heat kernel signature has affine invariability which can be used to extract the correct feature points of the human model in different postures. We adopt the method of geodesic distance to realize the hierarchical segmentation of human model after obtaining the semantic feature points of human model. The experimental results show that the method can overcome the defect of geodesic distance feature extraction. The human body models with different postures can be obtained with the model segmentation results of human semantic characteristics

Remote Sensing of the Oceans

This book covers different topics in the framework of remote sensing of the oceans. Latest research advancements and brand-new studies are presented that address the exploitation of remote sensing instruments and simulation tools to improve the understanding of ocean processes and enable cutting-edge applications with the aim of preserving the ocean environment and supporting the blue economy. Hence, this book provides a reference framework for state-of-the-art remote sensing methods that deal with the generation of added-value products and the geophysical information retrieval in related fields, including: Oil spill detection and discrimination; Analysis of tropical cyclones and sea echoes; Shoreline and aquaculture area extraction; Monitoring coastal marine litter and moving vessels; Processing of SAR, HF radar and UAV measurements

Sonar image interpretation for sub-sea operations

Mine Counter-Measure (MCM) missions are conducted to neutralise underwater explosives. Automatic Target Recognition (ATR) assists operators by increasing the speed and accuracy of data review. ATR embedded on vehicles enables adaptive missions which increase the speed of data acquisition. This thesis addresses three challenges; the speed of data processing, robustness of ATR to environmental conditions and the large quantities of data required to train an algorithm. The main contribution of this thesis is a novel ATR algorithm. The algorithm uses features derived from the projection of 3D boxes to produce a set of 2D templates. The template responses are independent of grazing angle, range and target orientation. Integer skewed integral images, are derived to accelerate the calculation of the template responses. The algorithm is compared to the Haar cascade algorithm. For a single model of sonar and cylindrical targets the algorithm reduces the Probability of False Alarm (PFA) by 80% at a Probability of Detection (PD) of 85%. The algorithm is trained on target data from another model of sonar. The PD is only 6% lower even though no representative target data was used for training. The second major contribution is an adaptive ATR algorithm that uses local sea-floor characteristics to address the problem of ATR robustness with respect to the local environment. A dual-tree wavelet decomposition of the sea-floor and an Markov Random Field (MRF) based graph-cut algorithm is used to segment the terrain. A Neural Network (NN) is then trained to filter ATR results based on the local sea-floor context. It is shown, for the Haar Cascade algorithm, that the PFA can be reduced by 70% at a PD of 85%. Speed of data processing is addressed using novel pre-processing techniques. The standard three class MRF, for sonar image segmentation, is formulated using graph-cuts. Consequently, a 1.2 million pixel image is segmented in 1.2 seconds. Additionally, local estimation of class models is introduced to remove range dependent segmentation quality. Finally, an A* graph search is developed to remove the surface return, a line of saturated pixels often detected as false alarms by ATR. The A* search identifies the surface return in 199 of 220 images tested with a runtime of 2.1 seconds. The algorithm is robust to the presence of ripples and rocks

Quantitative analysis with machine learning models for multi-parametric brain imaging data

Gliomas are considered to be the most common primary adult malignant brain tumor. With the dramatic increases in computational power and improvements in image analysis algorithms, computer-aided medical image analysis has been introduced into clinical applications. Precision tumor grading and genotyping play an indispensable role in clinical diagnosis, treatment and prognosis. Gliomas diagnostic procedures include histopathological imaging tests, molecular imaging scans and tumor grading. Pathologic review of tumor morphology in histologic sections is the traditional method for cancer classification and grading, yet human study has limitations that can result in low reproducibility and inter-observer agreement. Compared with histopathological images, Magnetic resonance (MR) imaging present the different structure and functional features, which might serve as noninvasive surrogates for tumor genotypes. Therefore, computer-aided image analysis has been adopted in clinical application, which might partially overcome these shortcomings due to its capacity to quantitatively and reproducibly measure multilevel features on multi-parametric medical information. Imaging features obtained from a single modal image do not fully represent the disease, so quantitative imaging features, including morphological, structural, cellular and molecular level features, derived from multi-modality medical images should be integrated into computer-aided medical image analysis. The image quality differentiation between multi-modality images is a challenge in the field of computer-aided medical image analysis. In this thesis, we aim to integrate the quantitative imaging data obtained from multiple modalities into mathematical models of tumor prediction response to achieve additional insights into practical predictive value. Our major contributions in this thesis are: 1. Firstly, to resolve the imaging quality difference and observer-dependent in histological image diagnosis, we proposed an automated machine-learning brain tumor-grading platform to investigate contributions of multi-parameters from multimodal data including imaging parameters or features from Whole Slide Images (WSI) and the proliferation marker KI-67. For each WSI, we extract both visual parameters such as morphology parameters and sub-visual parameters including first-order and second-order features. A quantitative interpretable machine learning approach (Local Interpretable Model-Agnostic Explanations) was followed to measure the contribution of features for single case. Most grading systems based on machine learning models are considered “black boxes,” whereas with this system the clinically trusted reasoning could be revealed. The quantitative analysis and explanation may assist clinicians to better understand the disease and accordingly to choose optimal treatments for improving clinical outcomes. 2. Based on the automated brain tumor-grading platform we propose, multimodal Magnetic Resonance Images (MRIs) have been introduced in our research. A new imaging–tissue correlation based approach called RA-PA-Thomics was proposed to predict the IDH genotype. Inspired by the concept of image fusion, we integrate multimodal MRIs and the scans of histopathological images for indirect, fast, and cost saving IDH genotyping. The proposed model has been verified by multiple evaluation criteria for the integrated data set and compared to the results in the prior art. The experimental data set includes public data sets and image information from two hospitals. Experimental results indicate that the model provided improves the accuracy of glioma grading and genotyping

Automated Resolution Selection for Image Segmentation

It is well known in image processing in general, and hence in image segmentation in particular, that computational cost increases rapidly with the number and dimensions of the images to be processed. Several fields, such as astronomy, remote sensing, and medical imaging, use very large images, which might also be 3D and/or captured at several frequency bands, all adding to the computational expense. Multiresolution analysis is one method of increasing the efficiency of the segmentation process. One multiresolution approach is the coarse-to-fine segmentation strategy, whereby the segmentation starts at a coarse resolution and is then fine-tuned during subsequent steps. Until now, the starting resolution for segmentation has been selected arbitrarily with no clear selection criteria. The research conducted for this thesis showed that starting from different resolutions for image segmentation results in different accuracies and speeds, even for images from the same dataset. An automated method for resolution selection for an input image would thus be beneficial. This thesis introduces a framework for the selection of the best resolution for image segmentation. First proposed is a measure for defining the best resolution based on user/system criteria, which offers a trade-off between accuracy and time. A learning approach is then described for the selection of the resolution, whereby extracted image features are mapped to the previously determined best resolution. In the learning process, class (i.e., resolution) distribution is imbalanced, making effective learning from the data difficult. A variant of AdaBoost, called RAMOBoost, is therefore used in this research for the learning-based selection of the best resolution for image segmentation. RAMOBoost is designed specifically for learning from imbalanced data. Two sets of features are used: Local Binary Patterns (LBP) and statistical features. Experiments conducted with four datasets using three different segmentation algorithms show that the resolutions selected through learning enable much faster segmentation than the original ones, while retaining at least the original accuracy. For three of the four datasets used, the segmentation results obtained with the proposed framework were significantly better than with the original resolution with respect to both accuracy and time

Segmentation, Super-resolution and Fusion for Digital Mammogram Classification

Mammography is one of the most common and effective techniques used by radiologists for the early detection of breast cancer. Recently, computer-aided detection/diagnosis (CAD) has become a major research topic in medical imaging and has been widely applied in clinical situations. According to statics, early detection of cancer can reduce the mortality rates by 30% to 70%, therefore detection and diagnosis in the early stage are very important. CAD systems are designed primarily to assist radiologists in detecting and classifying abnormalities in medical scan images, but the main challenges hindering their wider deployment is the difficulty in achieving accuracy rates that help improve radiologists’ performance. The detection and diagnosis of breast cancer face two main issues: the accuracy of the CAD system, and the radiologists’ performance in reading and diagnosing mammograms. This thesis focused on the accuracy of CAD systems. In particular, we investigated two main steps of CAD systems; pre-processing (enhancement and segmentation), feature extraction and classification. Through this investigation, we make five main contributions to the field of automatic mammogram analysis. In automated mammogram analysis, image segmentation techniques are employed in breast boundary or region-of-interest (ROI) extraction. In most Medio-Lateral Oblique (MLO) views of mammograms, the pectoral muscle represents a predominant density region and it is important to detect and segment out this muscle region during pre-processing because it could be bias to the detection of breast cancer. An important reason for the breast border extraction is that it will limit the search-zone for abnormalities in the region of the breast without undue influence from the background of the mammogram. Therefore, we propose a new scheme for breast border extraction, artifact removal and removal of annotations, which are found in the background of mammograms. This was achieved using an local adaptive threshold that creates a binary mask for the images, followed by the use of morphological operations. Furthermore, an adaptive algorithm is proposed to detect and remove the pectoral muscle automatically. Feature extraction is another important step of any image-based pattern classification system. The performance of the corresponding classification depends very much on how well the extracted features represent the object of interest. We investigated a range of different texture feature sets such as Local Binary Pattern Histogram (LBPH), Histogram of Oriented Gradients (HOG) descriptor, and Gray Level Co-occurrence Matrix (GLCM). We propose the use of multi-scale features based on wavelet and local binary patterns for mammogram classification. We extract histograms of LBP codes from the original image as well as the wavelet sub-bands. Extracted features are combined into a single feature set. Experimental results show that our proposed method of combining LBPH features obtained from the original image and with LBPH features obtained from the wavelet domain increase the classification accuracy (sensitivity and specificity) when compared with LBPH extracted from the original image. The feature vector size could be large for some types of feature extraction schemes and they may contain redundant features that could have a negative effect on the performance of classification accuracy. Therefore, feature vector size reduction is needed to achieve higher accuracy as well as efficiency (processing and storage). We reduced the size of the features by applying principle component analysis (PCA) on the feature set and only chose a small number of eigen components to represent the features. Experimental results showed enhancement in the mammogram classification accuracy with a small set of features when compared with using original feature vector. Then we investigated and propose the use of the feature and decision fusion in mammogram classification. In feature-level fusion, two or more extracted feature sets of the same mammogram are concatenated into a single larger fused feature vector to represent the mammogram. Whereas in decision-level fusion, the results of individual classifiers based on distinct features extracted from the same mammogram are combined into a single decision. In this case the final decision is made by majority voting among the results of individual classifiers. Finally, we investigated the use of super resolution as a pre-processing step to enhance the mammograms prior to extracting features. From the preliminary experimental results we conclude that using enhanced mammograms have a positive effect on the performance of the system. Overall, our combination of proposals outperforms several existing schemes published in the literature