Identifying Critical Regions for Robot Planning Using Convolutional Neural Networks

abstract: In this thesis, a new approach to learning-based planning is presented where critical regions of an environment with low probability measure are learned from a given set of motion plans. Critical regions are learned using convolutional neural networks (CNN) to improve sampling processes for motion planning (MP). In addition to an identification network, a new sampling-based motion planner, Learn and Link, is introduced. This planner leverages critical regions to overcome the limitations of uniform sampling while still maintaining guarantees of correctness inherent to sampling-based algorithms. Learn and Link is evaluated against planners from the Open Motion Planning Library (OMPL) on an extensive suite of challenging navigation planning problems. This work shows that critical areas of an environment are learnable, and can be used by Learn and Link to solve MP problems with far less planning time than existing sampling-based planners.Dissertation/ThesisMasters Thesis Computer Science 201

Hierarchical Manipulation for Constructing Free Standing Structures

abstract: In order for a robot to solve complex tasks in real world, it needs to compute discrete, high-level strategies that can be translated into continuous movement trajectories. These problems become increasingly difficult with increasing numbers of objects and domain constraints, as well as with the increasing degrees of freedom of robotic manipulator arms. The first part of this thesis develops and investigates new methods for addressing these problems through hierarchical task and motion planning for manipulation with a focus on autonomous construction of free-standing structures using precision-cut planks. These planks can be arranged in various orientations to design complex structures; reliably and autonomously building such structures from scratch is computationally intractable due to the long planning horizon and the infinite branching factor of possible grasps and placements that the robot could make. An abstract representation is developed for this class of problems and show how pose generators can be used to autonomously compute feasible robot motion plans for constructing a given structure. The approach was evaluated through simulation and on a real ABB YuMi robot. Results show that hierarchical algorithms for planning can effectively overcome the computational barriers to solving such problems. The second part of this thesis proposes a deep learning-based algorithm to identify critical regions for motion planning. Further investigation is done whether these learned critical regions can be translated to learn high-level landmark actions for automated planning.Dissertation/ThesisMasters Thesis Computer Science 201

Digital Oculomotor Biomarkers in Dementia

Dementia is an umbrella term that covers a number of neurodegenerative syndromes featuring gradual disturbance of various cognitive functions that are severe enough to interfere with tasks of daily life. The diagnosis of dementia occurs frequently when pathological changes have been developing for years, symptoms of cognitive impairment are evident and the quality of life of the patients has already been deteriorated significantly. Although brain imaging and fluid biomarkers allow the monitoring of disease progression in vivo, they are expensive, invasive and not necessarily diagnostic in isolation. Recent studies suggest that eye-tracking technology is an innovative tool that holds promise for accelerating early detection of the disease, as well as, supporting the development of strategies that minimise impairment during every day activities. However, the optimal methods for quantitative evaluation of oculomotor behaviour during complex and naturalistic tasks in dementia have yet to be determined. This thesis investigates the development of computational tools and techniques to analyse eye movements of dementia patients and healthy controls under naturalistic and less constrained scenarios to identify novel digital oculomotor biomarkers. Three key contributions are made. First, the evaluation of the role of environment during navigation in patients with typical Alzheimer disease and Posterior Cortical Atrophy compared to a control group using a combination of eye movement and egocentric video analysis. Secondly, the development of a novel method of extracting salient features directly from the raw eye-tracking data of a mixed sample of dementia patients during a novel instruction-less cognitive test to detect oculomotor biomarkers of dementia-related cognitive dysfunction. Third, the application of unsupervised anomaly detection techniques for visualisation of oculomotor anomalies during various cognitive tasks. The work presented in this thesis furthers our understanding of dementia-related oculomotor dysfunction and gives future research direction for the development of computerised cognitive tests and ecological interventions

Deep Learning Methods for 3D Aerial and Satellite Data

Recent advances in digital electronics have led to an overabundance of observations from electro-optical (EO) imaging sensors spanning high spatial, spectral and temporal resolution. This unprecedented volume, variety, and velocity is overwhelming our capacity to manage and translate that data into actionable information. Although decades of image processing research have taken the human out of the loop for many important tasks, the human analyst is still an irreplaceable link in the image exploitation chain, especially for more complex tasks requiring contextual understanding, memory, discernment, and learning. If knowledge discovery is to keep pace with the growing availability of data, new processing paradigms are needed in order to automate the analysis of earth observation imagery and ease the burden of manual interpretation. To address this gap, this dissertation advances fundamental and applied research in deep learning for aerial and satellite imagery. We show how deep learning---a computational model inspired by the human brain---can be used for (1) tracking, (2) classifying, and (3) modeling from a variety of data sources including full-motion video (FMV), Light Detection and Ranging (LiDAR), and stereo photogrammetry. First we assess the ability of a bio-inspired tracking method to track small targets using aerial videos. The tracker uses three kinds of saliency maps: appearance, location, and motion. Our approach achieves the best overall performance, including being the only method capable of handling long-term occlusions. Second, we evaluate the classification accuracy of a multi-scale fully convolutional network to label individual points in LiDAR data. Our method uses only the 3D-coordinates and corresponding low-dimensional spectral features for each point. Evaluated using the ISPRS 3D Semantic Labeling Contest, our method scored second place with an overall accuracy of 81.6\%. Finally, we validate the prediction capability of our neighborhood-aware network to model the bare-earth surface of LiDAR and stereo photogrammetry point clouds. The network bypasses traditionally-used ground classifications and seamlessly integrate neighborhood features with point-wise and global features to predict a per point Digital Terrain Model (DTM). We compare our results with two widely used softwares for DTM extraction, ENVI and LAStools. Together, these efforts have the potential to alleviate the manual burden associated with some of the most challenging and time-consuming geospatial processing tasks, with implications for improving our response to issues of global security, emergency management, and disaster response

A Survey on Deep Learning in Medical Image Analysis

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks and provide concise overviews of studies per application area. Open challenges and directions for future research are discussed.Comment: Revised survey includes expanded discussion section and reworked introductory section on common deep architectures. Added missed papers from before Feb 1st 201

Confocal Laser Endomicroscopy Image Analysis with Deep Convolutional Neural Networks

abstract: Rapid intraoperative diagnosis of brain tumors is of great importance for planning treatment and guiding the surgeon about the extent of resection. Currently, the standard for the preliminary intraoperative tissue analysis is frozen section biopsy that has major limitations such as tissue freezing and cutting artifacts, sampling errors, lack of immediate interaction between the pathologist and the surgeon, and time consuming. Handheld, portable confocal laser endomicroscopy (CLE) is being explored in neurosurgery for its ability to image histopathological features of tissue at cellular resolution in real time during brain tumor surgery. Over the course of examination of the surgical tumor resection, hundreds to thousands of images may be collected. The high number of images requires significant time and storage load for subsequent reviewing, which motivated several research groups to employ deep convolutional neural networks (DCNNs) to improve its utility during surgery. DCNNs have proven to be useful in natural and medical image analysis tasks such as classification, object detection, and image segmentation. This thesis proposes using DCNNs for analyzing CLE images of brain tumors. Particularly, it explores the practicality of DCNNs in three main tasks. First, off-the shelf DCNNs were used to classify images into diagnostic and non-diagnostic. Further experiments showed that both ensemble modeling and transfer learning improved the classifier’s accuracy in evaluating the diagnostic quality of new images at test stage. Second, a weakly-supervised learning pipeline was developed for localizing key features of diagnostic CLE images from gliomas. Third, image style transfer was used to improve the diagnostic quality of CLE images from glioma tumors by transforming the histology patterns in CLE images of fluorescein sodium-stained tissue into the ones in conventional hematoxylin and eosin-stained tissue slides. These studies suggest that DCNNs are opted for analysis of CLE images. They may assist surgeons in sorting out the non-diagnostic images, highlighting the key regions and enhancing their appearance through pattern transformation in real time. With recent advances in deep learning such as generative adversarial networks and semi-supervised learning, new research directions need to be followed to discover more promises of DCNNs in CLE image analysis.Dissertation/ThesisDoctoral Dissertation Neuroscience 201