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Trends in Computer-Aided Diagnosis Using Deep 2 Learning Techniques: A Review of Recent Studies on 3 Algorithm Development 4
With recent focus on deep neural network architectures for development of algorithms for computer-aided diagnosis (CAD), we provide a review of studies within the last 3 years (2015-2017) reported in selected top journals and conferences. 29 studies that met our inclusion criteria were reviewed to identify trends in this field and to inform future development. Studies have focused mostly on cancer-related diseases within internal medicine while diseases within gender-/age-focused fields like gynaecology/pediatrics have not received much focus. All reviewed studies employed image datasets, mostly sourced from publicly available databases (55.2%) and few based on data from human subjects (31%) and non-medical datasets (13.8%), while CNN architecture was employed in most (70%) of the studies. Confirmation of the effect of data manipulation on quality of output and adoption of multi-class rather than binary classification also require more focus. Future studies should leverage collaborations with medical experts to aid future with actual clinical testing with reporting based on some generally applicable index to enable comparison. Our next steps on plans for CAD development for osteoarthritis (OA), with plans to consider multi-class classification and comparison across deep learning approaches and unsupervised architectures were also highlighted
Deep Learning based HEp-2 Image Classification: A Comprehensive Review
Classification of HEp-2 cell patterns plays a significant role in the
indirect immunofluorescence test for identifying autoimmune diseases in the
human body. Many automatic HEp-2 cell classification methods have been proposed
in recent years, amongst which deep learning based methods have shown
impressive performance. This paper provides a comprehensive review of the
existing deep learning based HEp-2 cell image classification methods. These
methods perform HEp-2 image classification at two levels, namely, cell-level
and specimen-level. Both levels are covered in this review. At each level, the
methods are organized with a deep network usage based taxonomy. The core idea,
notable achievements, and key strengths and weaknesses of each method are
critically analyzed. Furthermore, a concise review of the existing HEp-2
datasets that are commonly used in the literature is given. The paper ends with
a discussion on novel opportunities and future research directions in this
field. It is hoped that this paper would provide readers with a thorough
reference of this novel, challenging, and thriving field.Comment: Published in Medical Image Analysi