14,148 research outputs found

    Hybrid Meta-Heuristics for Robust Scheduling

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    The production and delivery of rapidly perishable goods in distributed supply networks involves a number of tightly coupled decision and optimization problems regarding the just-in-time production scheduling and the routing of the delivery vehicles in order to satisfy strict customer specified time-windows. Besides dealing with the typical combinatorial complexity related to activity assignment and synchronization, effective methods must also provide robust schedules, coping with the stochastic perturbations (typically transportation delays) affecting the distribution process. In this paper, we propose a novel metaheuristic approach for robust scheduling. Our approach integrates mathematical programming, multi-objective evolutionary computation, and problem-specific constructive heuristics. The optimization algorithm returns a set of solutions with different cost and risk tradeoffs, allowing the analyst to adapt the planning depending on the attitude to risk. The effectiveness of the approach is demonstrated by a real-world case concerning the production and distribution of ready-mixed concrete.Meta-Heuristics;Multi-Objective Genetic Optimization;Robust Scheduling;Supply Networks

    Network-based business process management: embedding business logic in communications networks

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    Advanced Business Process Management (BPM) tools enable the decomposition of previously integrated and often ill-defined processes into re-usable process modules. These process modules can subsequently be distributed on the Internet over a variety of many different actors, each with their own specialization and economies-of-scale. The economic benefits of process specialization can be huge. However, how should such actors in a business network find, select, and control, the best partner for what part of the business process, in such a way that the best result is achieved? This particular management challenge requires more advanced techniques and tools in the enabling communications networks. An approach has been developed to embed business logic into the communications networks in order to optimize the allocation of business resources from a network point of view. Initial experimental results have been encouraging while at the same time demonstrating the need for more robust techniques in a future of massively distributed business processes.active networks;business process management;business protocols;embedded business logic;genetic algorithms;internet distributed process management;payment systems;programmable networks;resource optimization

    Inference of analytical thermodynamic models for biological networks

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    We present an automated algorithm for inferring analytical models of closed reactive biochemical mixtures, on the basis of standard approaches borrowed from thermodynamics and kinetic theory of gases. As an input, the method requires a number of steady states (i.e. an equilibria cloud in the phase-space), and at least one time series of measurements for each species. Validations are discussed for both the Michaelis-Menten mechanism (four species, two conservation laws) and the mitogen-activated protein kinase - MAPK - mechanism (eleven species, three conservation laws

    On green routing and scheduling problem

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    The vehicle routing and scheduling problem has been studied with much interest within the last four decades. In this paper, some of the existing literature dealing with routing and scheduling problems with environmental issues is reviewed, and a description is provided of the problems that have been investigated and how they are treated using combinatorial optimization tools

    Machine Learning for Fluid Mechanics

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    The field of fluid mechanics is rapidly advancing, driven by unprecedented volumes of data from field measurements, experiments and large-scale simulations at multiple spatiotemporal scales. Machine learning offers a wealth of techniques to extract information from data that could be translated into knowledge about the underlying fluid mechanics. Moreover, machine learning algorithms can augment domain knowledge and automate tasks related to flow control and optimization. This article presents an overview of past history, current developments, and emerging opportunities of machine learning for fluid mechanics. It outlines fundamental machine learning methodologies and discusses their uses for understanding, modeling, optimizing, and controlling fluid flows. The strengths and limitations of these methods are addressed from the perspective of scientific inquiry that considers data as an inherent part of modeling, experimentation, and simulation. Machine learning provides a powerful information processing framework that can enrich, and possibly even transform, current lines of fluid mechanics research and industrial applications.Comment: To appear in the Annual Reviews of Fluid Mechanics, 202

    Artificial Intelligence for Hospital Health Care:Application Cases and Answers to Challenges in European Hospitals

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    The development and implementation of artificial intelligence (AI) applications in health care contexts is a concurrent research and management question. Especially for hospitals, the expectations regarding improved efficiency and effectiveness by the introduction of novel AI applications are huge. However, experiences with real-life AI use cases are still scarce. As a first step towards structuring and comparing such experiences, this paper is presenting a comparative approach from nine European hospitals and eleven different use cases with possible application areas and benefits of hospital AI technologies. This is structured as a current review and opinion article from a diverse range of researchers and health care professionals. This contributes to important improvement options also for pandemic crises challenges, e.g., the current COVID-19 situation. The expected advantages as well as challenges regarding data protection, privacy, or human acceptance are reported. Altogether, the diversity of application cases is a core characteristic of AI applications in hospitals, and this requires a specific approach for successful implementation in the health care sector. This can include specialized solutions for hospitals regarding human-computer interaction, data management, and communication in AI implementation projects
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