4,979,927 research outputs found

    Generation Brexit officially launches in six new languages

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    Today Generation Brexit officially launches in six new languages - German, French, Italian, Spanish, Polish and Greek. With our new language sections, the Generation Brexit project becomes the only pan-European Brexit project of its type. We want to hear from YOU, in your language. After you set up an account (top right side of the page), you can either come ..

    Generation Challenge Program : Follow-Up on Executive Council and Science Council Inquiries

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    This report was prepared for the autumn 2004 meetings of ExCo and the Science Council. It was later discussed during the CGIAR Business Meeting at AGM 2004. The report is a detailed response to inquiries made by the Executive Council and the Science Council regarding the challenge program's goals and added values

    National Apology to the Stolen Generations

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    The University of Notre Dame Australia, Broome Campus will hold a stall in support of the Kimberley Stolen Generation, please come and show your support

    National Apology Day

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    Event Flyer for Community Discussion on OneDayton

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    Event flyer for a June 5, 2014 roundtable discussion on regional cooperation and restructuring local government. The event was for members of Leadership Dayton and Generation Dayton to discuss recommendations by the organization OneDayton

    Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg depression rating scale, the gold standard clinician rating scale : a meta-analysis of randomised placebo-controlled trials

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    It has been claimed that efficacy estimates based on the Hamilton Depression Rating-Scale (HDRS) underestimate antidepressants true treatment effects due to the instrument's poor psychometric properties. The aim of this study is to compare efficacy estimates based on the HDRS with the gold standard procedure, the Montgomery-Asberg Depression Rating-Scale (MADRS)

    An Evening with Dean Cole

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    Join us for a unique opportunity to get to know Dean Cole, learn about his inspirational story as a first-generation lawyer, and hear his perspective, advice, and hope for the future. ND Law students, faculty, and staff are welcome. 4:30 PM Doors open to McCartan Courtroom 5-6 PM A talk and Q&A with Dean Marcus Cole in McCartan Courtroom 6-7:30 PM Catered reception in Eck Hall Atriumhttps://scholarship.law.nd.edu/ndls_posters/1604/thumbnail.jp

    Next generation sequencing in cancer: opportunities and challenges for precision cancer medicine

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    Over the past decade, testing the genes of patients and their specific cancer types has become standardized practice in medical oncology since somatic mutations, changes in gene expression and epigenetic modifications are all hallmarks of cancer. However, while cancer genetic assessment has been limited to single biomarkers to guide the use of therapies, improvements in nucleic acid sequencing technologies and implementation of different genome analysis tools have enabled clinicians to detect these genomic alterations and identify functional and disease-associated genomic variants. Next-generation sequencing (NGS) technologies have provided clues about therapeutic targets and genomic markers for novel clinical applications when standard therapy has failed. While Sanger sequencing, an accurate and sensitive approach, allows for the identification of potential novel variants, it is however limited by the single amplicon being interrogated. Similarly, quantitative and qualitative profiling of gene expression changes also represents a challenge for the cancer field. Both RT-PCR and microarrays are efficient approaches, but are limited to the genes present on the array or being assayed. This leaves vast swaths of the transcriptome, including non-coding RNAs and other features, unexplored. With the advent of the ability to collect and analyze genomic sequence data in a timely fashion and at an ever-decreasing cost, many of these limitations have been overcome and are being incorporated into cancer research and diagnostics giving patients and clinicians new hope for targeted and personalized treatment. Below we highlight the various applications of next-generation sequencing in precision cancer medicine

    Content determination in GRE : evaluating the evaluator

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    In this paper, we discuss the evaluation mea- sures proposed in a number of recent papers as- sociated with the TUNA project1, and which have become an important component of the First NLG Shared Task and Evaluation Cam- paign (STEC) on attribute selection for referring expressions generation. Focusing on reference to individual objects, we discuss what such evalu- ation measures should be expected to achieve, and what alternative measures merit considera- tion.peer-reviewe

    Attribute selection for referring expression generation : new algorithms and evaluation methods

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    Referring expression generation has recently been the subject of the first Shared Task Challenge in NLG. In this paper, we analyse the systems that participated in the Challenge in terms of their algorithmic properties, comparing new techniques to classic ones, based on results from a new human task-performance experiment and from the intrinsic measures that were used in the Challenge. We also consider the relationship between different evaluation methods, showing that extrinsic task-performance experiments and intrinsic evaluation methods yield results that are not significantly correlated. We argue that this highlights the importance of including extrinsic evaluation methods in comparative NLG evaluations.peer-reviewe
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