Towards a human eye behavior model by applying Data Mining Techniques on Gaze Information from IEC

In this paper, we firstly present what is Interactive Evolutionary Computation (IEC) and rapidly how we have combined this artificial intelligence technique with an eye-tracker for visual optimization. Next, in order to correctly parameterize our application, we present results from applying data mining techniques on gaze information coming from experiments conducted on about 80 human individuals

A Novel Long-term, Multi-Channel and Non-invasive Electrophysiology Platform for Zebrafish.

Zebrafish are a popular vertebrate model for human neurological disorders and drug discovery. Although fecundity, breeding convenience, genetic homology and optical transparency have been key advantages, laborious and invasive procedures are required for electrophysiological studies. Using an electrode-integrated microfluidic system, here we demonstrate a novel multichannel electrophysiology unit to record multiple zebrafish. This platform allows spontaneous alignment of zebrafish and maintains, over days, close contact between head and multiple surface electrodes, enabling non-invasive long-term electroencephalographic recording. First, we demonstrate that electrographic seizure events, induced by pentylenetetrazole, can be reliably distinguished from eye or tail movement artifacts, and quantifiably identified with our unique algorithm. Second, we show long-term monitoring during epileptogenic progression in a scn1lab mutant recapitulating human Dravet syndrome. Third, we provide an example of cross-over pharmacology antiepileptic drug testing. Such promising features of this integrated microfluidic platform will greatly facilitate high-throughput drug screening and electrophysiological characterization of epileptic zebrafish

Investigating the effectiveness of an efficient label placement method using eye movement data

This paper focuses on improving the efficiency and effectiveness of dynamic and interactive maps in relation to the user. A label placement method with an improved algorithmic efficiency is presented. Since this algorithm has an influence on the actual placement of the name labels on the map, it is tested if this efficient algorithms also creates more effective maps: how well is the information processed by the user. We tested 30 participants while they were working on a dynamic and interactive map display. Their task was to locate geographical names on each of the presented maps. Their eye movements were registered together with the time at which a given label was found. The gathered data reveal no difference in the user's response times, neither in the number and the duration of the fixations between both map designs. The results of this study show that the efficiency of label placement algorithms can be improved without disturbing the user's cognitive map. Consequently, we created a more efficient map without affecting its effectiveness towards the user

Modeling Task Effects in Human Reading with Neural Attention

Humans read by making a sequence of fixations and saccades. They often skip words, without apparent detriment to understanding. We offer a novel explanation for skipping: readers optimize a tradeoff between performing a language-related task and fixating as few words as possible. We propose a neural architecture that combines an attention module (deciding whether to skip words) and a task module (memorizing the input). We show that our model predicts human skipping behavior, while also modeling reading times well, even though it skips 40% of the input. A key prediction of our model is that different reading tasks should result in different skipping behaviors. We confirm this prediction in an eye-tracking experiment in which participants answers questions about a text. We are able to capture these experimental results using the our model, replacing the memorization module with a task module that performs neural question answering

Aerospace medicine and biology: A continuing bibliography with indexes, supplement 197, September 1979

This bibliography lists 193 reports, articles, and other documents introduced into the NASA scientific and technical information system in August 1979

Quantifying sleep architecture dynamics and individual differences using big data and Bayesian networks

The pattern of sleep stages across a night (sleep architecture) is influenced by biological, behavioral, and clinical variables. However, traditional measures of sleep architecture such as stage proportions, fail to capture sleep dynamics. Here we quantify the impact of individual differences on the dynamics of sleep architecture and determine which factors or set of factors best predict the next sleep stage from current stage information. We investigated the influence of age, sex, body mass index, time of day, and sleep time on static (e.g. minutes in stage, sleep efficiency) and dynamic measures of sleep architecture (e.g. transition probabilities and stage duration distributions) using a large dataset of 3202 nights from a non-clinical population. Multi-level regressions show that sex effects duration of all Non-Rapid Eye Movement (NREM) stages, and age has a curvilinear relationship for Wake After Sleep Onset (WASO) and slow wave sleep (SWS) minutes. Bayesian network modeling reveals sleep architecture depends on time of day, total sleep time, age and sex, but not BMI. Older adults, and particularly males, have shorter bouts (more fragmentation) of Stage 2, SWS, and they transition less frequently to these stages. Additionally, we showed that the next sleep stage and its duration can be optimally predicted by the prior 2 stages and age. Our results demonstrate the potential benefit of big data and Bayesian network approaches in quantifying static and dynamic architecture of normal sleep