The effectiveness of DNA databases in relation to their purpose and content : a systematic review

Different stakeholders use forensic DNA databases for different purposes; for example, law enforcement agencies use them as an investigative tool to identify suspects, and criminologists use them to study the offending patterns of unidentified suspects. A number of researchers have already studied their effectiveness, but none has performed an overview of the relevant literature. Such an overview could help future researchers and policymakers by evaluating their creation, use and expansion. Using a systematic review, this article synthesizes the most relevant research into the effectiveness of forensic DNA databases published between January 1985 and March 2018. We report the results of the selected studies and look deeper into the evidence by evaluating the relationship between the purpose, content, and effectiveness of DNA databases, three inseparable elements in this type of research. We classify the studies by purposes: (i) detection and clearance; (ii) deterrence; and (iii) criminological scientific knowledge. Each category uses different measurements to evaluate effectiveness. The majority of these studies report positive results, supporting the assumption that DNA databases are an effective tool for the police, society, and criminologists. (C) 2019 Elsevier B.V. All rights reserved

Reflections on student support in open and distance learning

This is a very interesting moment to reflect on Student Support in Open and Distance Learning (ODL). After some 10 years of the radical intrusion of a range of technologies, principally those grouped around what has been broadly termed ICT, we have the chance to see if and how the world of ODL has qualitatively changed. To begin with a historical perspective on the European context, as is well known correspondence education is said to have begun in England in 1844 with Isaac Pitman's shorthand course delivered by correspondence, using the new postal system, enabled in its turn by the rail system that was beginning to make travel and communication across England quicker than ever before (Shrestha, 1997). The crucial dimension of Pitman's system was that he corrected students' work and sent it back to them. Thus although separated from the teacher, students received feedback, together we can at least imagine with encouragement from their tutor

Whole-genome sequencing for national surveillance of Shiga toxin–producing Escherichia coli O157

Background. National surveillance of gastrointestinal pathogens, such as Shiga toxin–producing Escherichia coli O157 (STEC O157), is key to rapidly identifying linked cases in the distributed food network to facilitate public health interventions. In this study, we used whole-genome sequencing (WGS) as a tool to inform national surveillance of STEC O157 in terms of identifying linked cases and clusters and guiding epidemiological investigation. Methods. We retrospectively analyzed 334 isolates randomly sampled from 1002 strains of STEC O157 received by the Gastrointestinal Bacteria Reference Unit at Public Health England, Colindale, in 2012. The genetic distance between each isolate, as estimated by WGS, was calculated and phylogenetic methods were used to place strains in an evolutionary context. Results. Estimates of linked clusters representing STEC O157 outbreaks in England and Wales increased by 2-fold when WGS was used instead of traditional typing techniques. The previously unidentified clusters were often widely geographically distributed and small in size. Phylogenetic analysis facilitated identification of temporally distinct cases sharing common exposures and delineating those that shared epidemiological and temporal links. Comparison with multi locus variable number tandem repeat analysis (MLVA) showed that although MLVA is as sensitive as WGS, WGS provides a more timely resolution to outbreak clustering. Conclusions. WGS has come of age as a molecular typing tool to inform national surveillance of STEC O157; it can be used in real time to provide the highest strain-level resolution for outbreak investigation. WGS allows linked cases to be identified with unprecedented specificity and sensitivity that will facilitate targeted and appropriate public health investigations

Making Sense of Entrepreneurship Journals: Journal Rankings and Strategy Choices

Dozens of peer-reviewed, English language journals are currently published in our field. How ought we to evaluate them? This paper seeks to answer this question. To do so, we utilize both relevant literature and data on Entrepreneurship journals. The literature derives from both information science and other research areas that reflect on their journals. The data derives from six citation measures from Google Scholar, Scopus, and Web of Science. We find 59 currently published English language, peer reviewed journals in Entrepreneurship. Contestable judgments based on their impact measures suggest that one of these 59 could be considered as “A+, four as “A”, five as “AB”, eight as “B”, four as “BC”, 23 as “C”, thirteen as “barely detectable”, and one as “insufficient data but promising”. Journal rankings affect the resources and prestige accorded to business schools, disciplines and subdisciplines, and individual scholars. However, the need to fit evaluations to school strategy implies that no rating system, ours included, is definitive. Multiple measures are needed, letter grades are misleading, and journal rankings should match the institution’s strategy and priorities in stakeholder service. A wider purpose of this study is to alert readers to the range of current methodologies and the limits of conventional rankings. Our conclusions appear innocuous, but standard practice is to use restrictive measures, to employ letter grades, and to prioritize only one stakeholder: scholars. These practices are poorly suited to the Entrepreneurship field

European Regional Science: Between Economy of Culture and Economy of Catastrophes (Review of the ERSA 2005 Amsterdam Congress Reports)

ERSA Congress can be seen as laboratory of ideas with broad representation not only European, but also scientists from US, Japan, Korea, Brazil, African and Asian countries. With very high speed new thoughts and phenomena from the European regional scientific community appear on the stages of the ERSA annual Congresses. Three new features were characteristic for the 2005 ERSA Congress in comparison with the previous ones. First, special focus on the factors of density in the regional development. That was not surprising as the meeting was held in the city of Amsterdam with the highest density in Europe where land and space are scarce goods. Second, integrative tendencies in attempt to use natural factors to explain traditional phenomena of the regional science. Issues of land and water management coincide with economic growth and regional development in many reports. Third, for the first time theme of networks and network society was embedded in many sections of the Congress and in the very title of the Congress itself. All these aspects as participants demonstrated could be positive creative factors increasing cultural assets of the European regions, efficiency of the knowledge transfer, leisure activities; or negative as the source of disaster and risk for human beings. Density factors (lack of people or lack of space?) divide European regional science into two sciences – urban for the populated regions and regional for the territories scarcely populated with very different themes, methods and tools of research. Housing markets, urban sprawl and commuting patterns are popular topics in the first case; labour markets and human capital in the second case. New Economic Geography models work smoothly in the first regions but are inappropriate in the second. Competition is harder in the labour markets of the populated regions but is softer in the regions with scattered population where it is substituted by the forces of cooperation. Contemporary regional society can be sustainable only as network society. In the reports networks were examined on different levels: a) as transportation networks in the investment national or interregional projects; b) as policentricity urban structures replacing Cristaller’s hierarchy of central places; c) as public-public, public-private partnerships combining public and private stakeholders in the decision-making process. Transition of the European regions from the industrial to network/service has begun 25 years ago. Position of the concrete region on this route determines clearly the type and intensity of its problem and research agenda. The more advanced is the region or nation on this route the more often terms like “reinventâ€, “rethinkâ€, “revisited†are used in the scientific community. Rediscovery of the old concepts, definitions, essence (as Amsterdam Congress demonstrated) is very creative and challenging process of the post-industrial regional science.

Transferring intermediate technologies to rural enterprises in developing economies: a conceptual framework

This paper integrates the contributions from different branches of the technology transfer literature to identify enablers driving the transfer of intermediate or appropriate technologies to recipients in rural areas of developing economies. An in-depth analysis of the literature shows that many enablers identified in the literature focus on high technology transfers and are of limited relevance in the context of rural enterprises. Other important enablers in this specific setting are ignored or insufficiently considered. This paper proposes a framework comprising a specific set of enablers that facilitates technology transfer in rural enterprises in developing regional economies