1,806,432 research outputs found
Industrial strategy and the UK regions: Sectorally narrow and spatially blind
The UK government's new Industrial Strategy could have a significant impact on the country's regions and localities. However, this has received little attention to date. The analysis presented here examines the existing location of the sectors targeted by the first phase of the Industrial Strategy Challenge Fund and the location of the R&D laboratories likely to be first in line for funding. In focusing on an extremely narrow range of sectors, the Fund is likely to have limited impact on the UK's persistent regional inequalities. The activities eligible for support account for relatively little of manufacturing or the rest of the economy and the basis of this targeting and its potential distributional consequences are spatially blind. As such, it runs the risk of widening regional divides in prosperity
Elsevier
© 2021 The Author(s). Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license.Organizing pneumonia (OP) is a sub-acute process of pulmonary tissue repair secondary to lung injury, defined histopathologically by intra-alveolar buds of granulation tissue within the lumen of distal pulmonary airspaces. It can be either cryptogenic or secondary (SOP) to different clinical conditions, namely infections. Despite being nonspecific, its diagnosis can be made by the association of clinical and imaging criteria. We report two cases of OP associated to SARS-CoV-2 pneumonia, admitted at a Portuguese tertiary hospital unit dedicated to COVID-19. Both patients presented with severe respiratory failure with need of invasive mechanical ventilation. After initial recovery, there was worsening of dyspnea and hypoxemic respiratory failure with increase in inflammatory markers. Chest CT revealed an OP pattern. Other conditions such as superinfection, auto-immune disease and iatrogenic etiology, were excluded and corticotherapy at a dose of 1 mg/kg/day was administered. Chest CT follow up of both our patients showed complete resolution of OP pattern, with mild to moderate residual pulmonary fibrosis without honeycombing. There is no OP to SARS-CoV-2 case series yet published describing the progress of patients after corticotherapy, although the association between systemic corticosteroids and lower all-cause mortality in patients with COVID-19 has been recently established. It is possible that, as has been described with other viruses, OP secondary to SARS-CoV-2 represents an immunological process after initial infection, presenting with elevation of inflammatory markers and cytokines storm in the bloodstream and lung tissue, which may explain the favorable response to corticosteroids.info:eu-repo/semantics/publishedVersio
The Reed Elsevier stock price gap
This is the report of a limited study on the structural stock price differences between Reed and Elsevier. The purpose of this study is to provide an overview of the problem area and to formulate and discuss several hypotheses regarding the causes of this gap. The research was performed by interviewing bankers, financial analysts, academics and the Director Corporate Finance of Reed-Elsevier. Statistical evaluation was not the primary goal. A solution of the gap problem is not yet found.Mergers;Share Prices;Elsevier;Reed;business economics
Elsevier SciVai
Blok obsahuje 2 přednášky New research perspective – SciVal for the Czech Republic (Szymański, Krzysztof) a Using SciVal at the University of Bath (Robinson, Kate) a následnou společnou diskuzi
Radiation Testing of Electronics for the CMS Endcap Muon System
The electronics used in the data readout and triggering system for the
Compact Muon Solenoid (CMS) experiment at the Large Hadron Collider (LHC)
particle accelerator at CERN are exposed to high radiation levels. This
radiation can cause permanent damage to the electronic circuitry, as well as
temporary effects such as data corruption induced by Single Event Upsets. Once
the High Luminosity LHC (HL-LHC) accelerator upgrades are completed it will
have five times higher instantaneous luminosity than LHC, allowing for
detection of rare physics processes, new particles and interactions. Tests have
been performed to determine the effects of radiation on the electronic
components to be used for the Endcap Muon electronics project currently being
designed for installation in the CMS experiment in 2013. During these tests the
digital components on the test boards were operating with active data readout
while being irradiated with 55 MeV protons. In reactor tests, components were
exposed to 30 years equivalent levels of neutron radiation expected at the
HL-LHC. The highest total ionizing dose (TID) for the muon system is expected
at the inner-most portion of the CMS detector, with 8900 rad over ten years.
Our results show that Commercial Off-The-Shelf (COTS) components selected for
the new electronics will operate reliably in the CMS radiation environment
Collective flow from AA, pA to pp collisions - Toward a unified paradigm
I give an overview of the latest development in understanding collective
phenomena in high-multiplicity hadronic final state from relativistic
nucleus-nucleus, proton-nucleus and proton-proton collisions. Upon reviewing
the experimental data and confronting them with theoretical models, a unified
paradigm in describing the observed collectivity across all hadronic collision
systems is emerging. Potential future paths toward addressing key open
questions, especially on collectivity in small systems (pp, pA), are discussed.Comment: 9 pages, 6 figures, plenary contribution to Quark Matter 2017,
February 5-11 (2017), Chicago (IL), US
MEXIT: Maximal un-coupling times for stochastic processes
Classical coupling constructions arrange for copies of the \emph{same} Markov
process started at two \emph{different} initial states to become equal as soon
as possible. In this paper, we consider an alternative coupling framework in
which one seeks to arrange for two \emph{different} Markov (or other
stochastic) processes to remain equal for as long as possible, when started in
the \emph{same} state. We refer to this "un-coupling" or "maximal agreement"
construction as \emph{MEXIT}, standing for "maximal exit". After highlighting
the importance of un-coupling arguments in a few key statistical and
probabilistic settings, we develop an explicit \MEXIT construction for
stochastic processes in discrete time with countable state-space. This
construction is generalized to random processes on general state-space running
in continuous time, and then exemplified by discussion of \MEXIT for Brownian
motions with two different constant drifts.Comment: 28 page
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