2,890 research outputs found
Invited review: Epidemics on social networks
Since its first formulations almost a century ago, mathematical models for
disease spreading contributed to understand, evaluate and control the epidemic
processes.They promoted a dramatic change in how epidemiologists thought of the
propagation of infectious diseases.In the last decade, when the traditional
epidemiological models seemed to be exhausted, new types of models were
developed.These new models incorporated concepts from graph theory to describe
and model the underlying social structure.Many of these works merely produced a
more detailed extension of the previous results, but some others triggered a
completely new paradigm in the mathematical study of epidemic processes. In
this review, we will introduce the basic concepts of epidemiology, epidemic
modeling and networks, to finally provide a brief description of the most
relevant results in the field.Comment: 17 pages, 13 figure
Commentary on the use of the reproduction number R during the COVID-19 pandemic
Since the beginning of the COVID-19 pandemic, the reproduction number R has become a popular epidemiological metric used to communicate the state of the epidemic. At its most basic, R is defined as the average number of secondary infections caused by one primary infected individual. R seems convenient, because the epidemic is expanding if R>1 and contracting if R<1. The magnitude of R indicates by how much transmission needs to be reduced to control the epidemic. Using R in a naĂŻve way can cause new problems. The reasons for this are threefold: (1) There is not just one definition of R but many, and the precise definition of R affects both its estimated value and how it should be interpreted. (2) Even with a particular clearly defined R, there may be different statistical methods used to estimate its value, and the choice of method will affect the estimate. (3) The availability and type of data used to estimate R vary, and it is not always clear what data should be included in the estimation. In this review, we discuss when R is useful, when it may be of use but needs to be interpreted with care, and when it may be an inappropriate indicator of the progress of the epidemic. We also argue that careful definition of R, and the data and methods used to estimate it, can make R a more useful metric for future management of the epidemic
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