Medvedkine

Chris Marker’s portrait of Alexandre Medvedkine in the 1993 film Le tombeau d’Alexandre/The Last Bolshevik is highly instructive of his own relationship to Soviet cinema. Most especially, this difficult or troubled rapport with the antecedents to cinéma vérité in the West (and its protean formal properties, in terms of structure and often satirical-critical commentary) comes forth in the figures he assembles to comment upon Medvedkine’s life work. When Medvedkine’s Scast’e (Le Bonheur/Happiness) (1934) leaked to the West (c.1967), sent like an “SOS” in multiple bottles to various film archives (one by one from deep within the Soviet film world), Marker and SLON received a copy by way of Jacques Ledoux (curator of the Cinémathèque Royale de Belgique, in Belgium). The film opened the floodgates of a retrospective survey of Soviet filmmaking repressed and forgotten other than by remote and distant figures (partisans) who somehow survived the Stalinist purges of the 1930s

Gypsum-DL: an open-source program for preparing small-molecule libraries for structure-based virtual screening

Computational techniques such as structure-based virtual screening require carefully prepared 3D models of potential small-molecule ligands. Though powerful, existing commercial programs for virtual-library preparation have restrictive and/or expensive licenses. Freely available alternatives, though often effective, do not fully account for all possible ionization, tautomeric, and ring-conformational variants. We here present Gypsum-DL, a free, robust open-source program that addresses these challenges. As input, Gypsum-DL accepts virtual compound libraries in SMILES or flat SDF formats. For each molecule in the virtual library, it enumerates appropriate ionization, tautomeric, chiral, cis/trans isomeric, and ring-conformational forms. As output, Gypsum-DL produces an SDF file containing each molecular form, with 3D coordinates assigned. To demonstrate its utility, we processed 1558 molecules taken from the NCI Diversity Set VI and 56,608 molecules taken from a Distributed Drug Discovery (D3) combinatorial virtual library. We also used 4463 high-quality protein-ligand complexes from the PDBBind database to show that Gypsum-DL processing can improve virtual-screening pose prediction. Gypsum-DL is available free of charge under the terms of the Apache License, Version 2.0

Client/provider relationship: Library as client and art students as provider

What started as a discussion about how to bring more art into the library developed into a valuable collaboration with faculty and students that brought murals into the architecture library. The arts and architecture librarian reached out to one of the painting professors to discuss showcasing student work in the branch library, and the result was an elaborate mural project. The librarian worked with two professors in the Department of Art and Art History and their students in fall 2017 to bring this artwork to fruition. This article covers how the project developed and how it resulted in creating an inviting space to inspire learning

English-medium instruction in European higher education: review and future research.

The purpose of this volume has been to give an account of the status of English as a medium of instruction in various political, geographical and ideological contexts: Northern, Southern, Eastern, Western and Central Europe, regions at different stages of EMI implementation. It is our hope that the preceding chapters have given comparative insights into some of the discussions and issues associated with EMI in European higher education. While contributors have investigated a diverse set of empirical, pedagogical and political issues, many issues remain to be addressed in more detail. In these final few pages of the volume, we briefly review some of the main issues that have arisen in the preceding chapters and the broader EMI literature and propose further directions in methodological approaches, areas, and scopes