A Novel Adaptive Spectrum Noise Cancellation Approach for Enhancing Heartbeat Rate Monitoring in a Wearable Device

This paper presents a novel approach, Adaptive Spectrum Noise Cancellation (ASNC), for motion artifacts removal in Photoplethysmography (PPG) signals measured by an optical biosensor to obtain clean PPG waveforms for heartbeat rate calculation. One challenge faced by this optical sensing method is the inevitable noise induced by movement when the user is in motion, especially when the motion frequency is very close to the target heartbeat rate. The proposed ASNC utilizes the onboard accelerometer and gyroscope sensors to detect and remove the artifacts adaptively, thus obtaining accurate heartbeat rate measurement while in motion. The ASNC algorithm makes use of a commonly accepted spectrum analysis approaches in medical digital signal processing, discrete cosine transform, to carry out frequency domain analysis. Results obtained by the proposed ASNC have been compared to the classic algorithms, the adaptive threshold peak detection and adaptive noise cancellation. The mean (standard deviation) absolute error and mean relative error of heartbeat rate calculated by ASNC is 0.33 (0.57) beats·min-1 and 0.65%, by adaptive threshold peak detection algorithm is 2.29 (2.21) beats·min-1 and 8.38%, by adaptive noise cancellation algorithm is 1.70 (1.50) beats·min-1 and 2.02%. While all algorithms performed well with both simulated PPG data and clean PPG data collected from our Verity device in situations free of motion artifacts, ASNC provided better accuracy when motion artifacts increase, especially when motion frequency is very close to the heartbeat rate

Estimating Carotid Pulse and Breathing Rate from Near-infrared Video of the Neck

Objective: Non-contact physiological measurement is a growing research area that allows capturing vital signs such as heart rate (HR) and breathing rate (BR) comfortably and unobtrusively with remote devices. However, most of the approaches work only in bright environments in which subtle photoplethysmographic and ballistocardiographic signals can be easily analyzed and/or require expensive and custom hardware to perform the measurements. Approach: This work introduces a low-cost method to measure subtle motions associated with the carotid pulse and breathing movement from the neck using near-infrared (NIR) video imaging. A skin reflection model of the neck was established to provide a theoretical foundation for the method. In particular, the method relies on template matching for neck detection, Principal Component Analysis for feature extraction, and Hidden Markov Models for data smoothing. Main Results: We compared the estimated HR and BR measures with ones provided by an FDA-cleared device in a 12-participant laboratory study: the estimates achieved a mean absolute error of 0.36 beats per minute and 0.24 breaths per minute under both bright and dark lighting. Significance: This work advances the possibilities of non-contact physiological measurement in real-life conditions in which environmental illumination is limited and in which the face of the person is not readily available or needs to be protected. Due to the increasing availability of NIR imaging devices, the described methods are readily scalable.Comment: 21 pages, 15 figure

Optimal fiducial points for pulse rate variability analysis from forehead and finger PPG signals

Objective: The aim of this work is to evaluate and compare five fiducialpoints for the temporal location of each pulse wave from forehead and fingerphotoplethysmographic pulse waves signals (PPG) to perform pulse rate variability(PRV) analysis as a surrogate of heart rate variability (HRV) analysis. Approach: Forehead and finger PPG signals were recorded during tilt-table testsimultaneously to the ECG. Artifacts were detected and removed and, five fiducialpoints were computed: apex, middle-amplitude and foot points of the PPG signal,apex point of the first derivative signal and, the intersection point of the tangent tothe PPG waveform at the apex of the derivative PPG signal and the tangent to thefoot of the PPG pulse defined as intersecting tangents method. Pulse period (PP)time intervals series were obtained from both PPG signals and compared to the RRintervals obtained from the ECG. Heart and pulse rate variability signals (HRV andPRV) were estimated and, classical time and frequency domain indices were computed. Main Results: The middle-amplitude point of the PPG signal (nM), the apexpoint of the first derivative (n*A), and the tangents intersection point (nT) are themost suitable fiducial points for PRV analysis, which result in the lowest relativeerrors estimated between PRV and HRV indices, higher correlation coefficients and reliability indexes. Statistically significant differences according to the Wilcoxon testbetween PRV and HRV signals were found for the apex and foot fiducial points ofthe PPG, as well as the lowest agreement between RR and PP series according toBland-Altman analysis. Hence, they have been considered less accurate for variabilityanalysis. In addition, the relative errors are significantly lower fornMandn*Afeaturesby using Friedman statistics with Bonferroni multiple-comparison test and, we proposenMas the most accurate fiducial point. Based on our results, forehead PPG seems toprovide more reliable information for a PRV assessment than finger PPG. Significance: The accuracy of the pulse wave detections depends on the morphologyof the PPG. There is therefore a need to widely define the most accurate fiducial pointto perform a PRV analysis under non-stationary conditions based on different PPGsensor locations and signal acquisition techniques

Sources of inaccuracy in photoplethysmography for continuous cardiovascular monitoring

Photoplethysmography (PPG) is a low-cost, noninvasive optical technique that uses change in light transmission with changes in blood volume within tissue to provide information for cardiovascular health and fitness. As remote health and wearable medical devices become more prevalent, PPG devices are being developed as part of wearable systems to monitor parameters such as heart rate (HR) that do not require complex analysis of the PPG waveform. However, complex analyses of the PPG waveform yield valuable clinical information, such as: blood pressure, respiratory information, sympathetic nervous system activity, and heart rate variability. Systems aiming to derive such complex parameters do not always account for realistic sources of noise, as testing is performed within controlled parameter spaces. A wearable monitoring tool to be used beyond fitness and heart rate must account for noise sources originating from individual patient variations (e.g., skin tone, obesity, age, and gender), physiology (e.g., respiration, venous pulsation, body site of measurement, and body temperature), and external perturbations of the device itself (e.g., motion artifact, ambient light, and applied pressure to the skin). Here, we present a comprehensive review of the literature that aims to summarize these noise sources for future PPG device development for use in health monitoring

A multi-channel opto-electronic sensor to accurately monitor heart rate against motion artefact during exercise

This study presents the use of a multi-channel opto-electronic sensor (OEPS) to effectively monitor critical physiological parameters whilst preventing motion artefact as increasingly demanded by personal healthcare. The aim of this work was to study how to capture the heart rate (HR) efficiently through a well-constructed OEPS and a 3-axis accelerometer with wireless communication. A protocol was designed to incorporate sitting, standing, walking, running and cycling. The datasets collected from these activities were processed to elaborate sport physiological effects. t-test, Bland-Altman Agreement (BAA), and correlation to evaluate the performance of the OEPS were used against Polar and Mio-Alpha HR monitors. No differences in the HR were found between OEPS, and either Polar or Mio-Alpha (both p > 0.05); a strong correlation was found between Polar and OEPS (r: 0.96, p < 0.001); the bias of BAA 0.85 bpm, the standard deviation (SD) 9.20 bpm, and the limits of agreement (LOA) from −17.18 bpm to +18.88 bpm. For the Mio-Alpha and OEPS, a strong correlation was found (r: 0.96, p < 0.001); the bias of BAA 1.63 bpm, SD 8.62 bpm, LOA from −15.27 bpm to +18.58 bpm. These results demonstrate the OEPS to be capable of carrying out real time and remote monitoring of heart rate

Accurate wearable heart rate monitoring during physical exercises using PPG

Objective: The challenging task of heart rate (HR) estimation from the photoplethysmographic (PPG) signal, during intensive physical exercises is tackled in this paper. Methods: The study presents a detailed analysis of a novel algorithm (WFPV) that exploits a Wiener filter to attenuate the motion artifacts, a phase vocoder to refine the HR estimate and user-adaptive postprocessing to track the subject physiology. Additionally, an offline version of the HR estimation algorithm that uses Viterbi decoding is designed for scenarios that do not require online HR monitoring (WFPV+VD). The performance of the HR estimation systems is rigorously compared with existing algorithms on the publically available database of 23 PPG recordings. Results: On the whole dataset of 23 PPG recordings, the algorithms result in average absolute errors of 1.97 and 1.37 BPM in the online and offline modes, respectively. On the test dataset of 10 PPG recordings which were most corrupted with motion artifacts, WFPV has an error of 2.95 BPM on its own and 2.32 BPM in an ensemble with 2 existing algorithms. Conclusion: The error rate is significantly reduced when compared with the state-of-the art PPG-based HR estimation methods. Significance: The proposed system is shown to be accurate in the presence of strong motion artifacts and in contrast to existing alternatives has very few free parameters to tune. The algorithm has a low computational cost and can be used for fitness tracking and health monitoring in wearable devices. The Matlab implementation of the algorithm is provided online

Systems and methods for physiological signal enhancement and biometric extraction using non-invasive optical sensors

A system and method for signal processing to remove unwanted noise components including: (i) wavelength-independent motion artifacts such as tissue, bone and skin effects, and (ii) wavelength-dependent motion artifact/noise components such as venous blood pulsation and movement due to various sources including muscle pump, respiratory pump and physical perturbation. Disclosed are methods, analytics, and their uses for reliable perfusion monitoring, arterial oxygen saturation monitoring, heart rate monitoring during daily activities and in hospital settings and for extraction of physiological parameters such as respiration information, hemodynamic parameters, venous capacity, and fluid responsiveness. The system and methods disclosed are extendable to include monitoring platforms for perfusion, hypoxia, arrhythmia detection, airway obstruction detection and sleep disorders including apnea.Board of Regents, University of Texas Syste