Detecting bias due to input modelling in computer simulation

This is the first paper to approach the problem of bias in the output of a stochastic simulation due to using input distributions whose parameters were estimated from real-world data. We consider, in particular, the bias in simulation-based estimators of the expected value (long-run average) of the real-world system performance; this bias will be present even if one employs unbiased estimators of the input distribution parameters due to the (typically) nonlinear relationship between these parameters and the output response. To date this bias has been assumed to be negligible because it decreases rapidly as the quantity of real-world input data increases. While true asymptotically, this property does not imply that the bias is actually small when, as is always the case, data are finite. We present a delta-method approach to bias estimation that evaluates the nonlinearity of the expected-value performance surface as a function of the input-model parameters. Since this response surface is unknown, we propose an innovative experimental design to fit a response-surface model that facilitates a test for detecting a bias of a relevant size with specified power. We evaluate the method using controlled experiments, and demonstrate it through a realistic case study concerning a healthcare call centre

Detecting bias due to input modelling in computer simulation

Bias due to input modelling is almost always assumed negligible and ignored. It is known that increasing the amount of real-world data available for modelling input processes causes this form of bias to decrease faster than the variance due to input uncertainty. However, this does not mean bias is irrelevant when considering the error in a simulation performance measure caused by input modelling. In this paper we present a response surface approach to bias estimation in simulation models along with a diagnostic test for identifying, with controlled power, bias due to input modelling of a size that would be concerning to a practitioner

Understanding from Machine Learning Models

Simple idealized models seem to provide more understanding than opaque, complex, and hyper-realistic models. However, an increasing number of scientists are going in the opposite direction by utilizing opaque machine learning models to make predictions and draw inferences, suggesting that scientists are opting for models that have less potential for understanding. Are scientists trading understanding for some other epistemic or pragmatic good when they choose a machine learning model? Or are the assumptions behind why minimal models provide understanding misguided? In this paper, using the case of deep neural networks, I argue that it is not the complexity or black box nature of a model that limits how much understanding the model provides. Instead, it is a lack of scientific and empirical evidence supporting the link that connects a model to the target phenomenon that primarily prohibits understanding

Medical imaging analysis with artificial neural networks

Given that neural networks have been widely reported in the research community of medical imaging, we provide a focused literature survey on recent neural network developments in computer-aided diagnosis, medical image segmentation and edge detection towards visual content analysis, and medical image registration for its pre-processing and post-processing, with the aims of increasing awareness of how neural networks can be applied to these areas and to provide a foundation for further research and practical development. Representative techniques and algorithms are explained in detail to provide inspiring examples illustrating: (i) how a known neural network with fixed structure and training procedure could be applied to resolve a medical imaging problem; (ii) how medical images could be analysed, processed, and characterised by neural networks; and (iii) how neural networks could be expanded further to resolve problems relevant to medical imaging. In the concluding section, a highlight of comparisons among many neural network applications is included to provide a global view on computational intelligence with neural networks in medical imaging

Predictive Coding as a Model of Biased Competition in Visual Attention

Attention acts, through cortical feedback pathways, to enhance the response of cells encoding expected or predicted information. Such observations are inconsistent with the predictive coding theory of cortical function which proposes that feedback acts to suppress information predicted by higher-level cortical regions. Despite this discrepancy, this article demonstrates that the predictive coding model can be used to simulate a number of the effects of attention. This is achieved via a simple mathematical rearrangement of the predictive coding model, which allows it to be interpreted as a form of biased competition model. Nonlinear extensions to the model are proposed that enable it to explain a wider range of data

A review of applied methods in Europe for flood-frequency analysis in a changing environment

The report presents a review of methods used in Europe for trend analysis, climate change projections and non-stationary analysis of extreme precipitation and flood frequency. In addition, main findings of the analyses are presented, including a comparison of trend analysis results and climate change projections. Existing guidelines in Europe on design flood and design rainfall estimation that incorporate climate change are reviewed. The report concludes with a discussion of research needs on non-stationary frequency analysis for considering the effects of climate change and inclusion in design guidelines. Trend analyses are reported for 21 countries in Europe with results for extreme precipitation, extreme streamflow or both. A large number of national and regional trend studies have been carried out. Most studies are based on statistical methods applied to individual time series of extreme precipitation or extreme streamflow using the non-parametric Mann-Kendall trend test or regression analysis. Some studies have been reported that use field significance or regional consistency tests to analyse trends over larger areas. Some of the studies also include analysis of trend attribution. The studies reviewed indicate that there is some evidence of a general increase in extreme precipitation, whereas there are no clear indications of significant increasing trends at regional or national level of extreme streamflow. For some smaller regions increases in extreme streamflow are reported. Several studies from regions dominated by snowmelt-induced peak flows report decreases in extreme streamflow and earlier spring snowmelt peak flows. Climate change projections have been reported for 14 countries in Europe with results for extreme precipitation, extreme streamflow or both. The review shows various approaches for producing climate projections of extreme precipitation and flood frequency based on alternative climate forcing scenarios, climate projections from available global and regional climate models, methods for statistical downscaling and bias correction, and alternative hydrological models. A large number of the reported studies are based on an ensemble modelling approach that use several climate forcing scenarios and climate model projections in order to address the uncertainty on the projections of extreme precipitation and flood frequency. Some studies also include alternative statistical downscaling and bias correction methods and hydrological modelling approaches. Most studies reviewed indicate an increase in extreme precipitation under a future climate, which is consistent with the observed trend of extreme precipitation. Hydrological projections of peak flows and flood frequency show both positive and negative changes. Large increases in peak flows are reported for some catchments with rainfall-dominated peak flows, whereas a general decrease in flood magnitude and earlier spring floods are reported for catchments with snowmelt-dominated peak flows. The latter is consistent with the observed trends. The review of existing guidelines in Europe on design floods and design rainfalls shows that only few countries explicitly address climate change. These design guidelines are based on climate change adjustment factors to be applied to current design estimates and may depend on design return period and projection horizon. The review indicates a gap between the need for considering climate change impacts in design and actual published guidelines that incorporate climate change in extreme precipitation and flood frequency. Most of the studies reported are based on frequency analysis assuming stationary conditions in a certain time window (typically 30 years) representing current and future climate. There is a need for developing more consistent non-stationary frequency analysis methods that can account for the transient nature of a changing climate

Errors and Artefacts in Agent-Based Modelling

The objectives of this paper are to define and classify different types of errors and artefacts that can appear in the process of developing an agent-based model, and to propose activities aimed at avoiding them during the model construction and testing phases. To do this in a structured way, we review the main concepts of the process of developing such a model – establishing a general framework that summarises the process of designing, implementing, and using agent-based models. Within this framework we identify the various stages where different types of errors and artefacts may appear. Finally we propose activities that could be used to detect (and hence eliminate) each type of error or artefact.Verification, Replication, Artefact, Error, Agent-Based Modelling, Modelling Roles

Sensor failure detection system

Advanced concepts for detecting, isolating, and accommodating sensor failures were studied to determine their applicability to the gas turbine control problem. Five concepts were formulated based upon such techniques as Kalman filters and a screening process led to the selection of one advanced concept for further evaluation. The selected advanced concept uses a Kalman filter to generate residuals, a weighted sum square residuals technique to detect soft failures, likelihood ratio testing of a bank of Kalman filters for isolation, and reconfiguring of the normal mode Kalman filter by eliminating the failed input to accommodate the failure. The advanced concept was compared to a baseline parameter synthesis technique. The advanced concept was shown to be a viable concept for detecting, isolating, and accommodating sensor failures for the gas turbine applications

The evaluation of failure detection and isolation algorithms for restructurable control

Three failure detection and identification techniques were compared to determine their usefulness in detecting and isolating failures in an aircraft flight control system; excluding sensor and flight control computer failures. The algorithms considered were the detection filter, the Generalized Likelihood Ratio test and the Orthogonal Series Generalized Likelihood Ratio test. A modification to the basic detection filter is also considered which uses secondary filtering of the residuals to produce unidirectional failure signals. The algorithms were evaluated by testing their ability to detect and isolate control surface failures in a nonlinear simulation of a C-130 aircraft. It was found that failures of some aircraft controls are difficult to distinguish because they have a similar effect on the dynamics of the vehicle. Quantitative measures for evaluating the distinguishability of failures are considered. A system monitoring strategy for implementing the failure detection and identification techniques was considered. This strategy identified the mix of direct measurement of failures versus the computation of failure necessary for implementation of the technology in an aircraft system