27,932 research outputs found

    Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine

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    The organisms thriving under extreme conditions better than any other organism living on Earth, fascinate by their hostile growing parameters, physiological features, and their production of valuable bioactive metabolites. This is the case of microorganisms (bacteria, archaea, and fungi) that grow optimally at high salinities and are able to produce biomolecules of pharmaceutical interest for therapeutic applications. As along as the microbiota is being approached by massive sequencing, novel insights are revealing the environmental conditions on which the compounds are produced in the microbial community without more stress than sharing the same substratum with their peers, the salt. In this review are reported the molecules described and produced by halophilic microorganisms with a spectrum of action in vitro: antimicrobial and anticancer. The action mechanisms of these molecules, the urgent need to introduce alternative lead compounds and the current aspects on the exploitation and its limitations are discussed.España, MINECO CGL2017-83385-

    Arsenic in drinking water wells on the Bolivian high plain: field monitoring and effect of salinity on removal efficiency of iron-oxides-containing filters

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    In the rural areas around Oruro (Bolivia), untreated groundwater is used directly as drinking water. This research aimed to evaluate the general drinking water quality, with focus on arsenic (As) concentrations, based on analysis of 67 samples from about 16 communities of the Oruro district. Subsequently a filter using Iron Oxide Coated Sand (IOCS) and a filter using a Composite Iron Matrix (CIM) were tested for their arsenic removal capacity using synthetic water mimicking real groundwater. Heavy metal concentrations in the sampled drinking water barely exceeded WHO guidelines. Arsenic concentrations reached values up to 964 mu g L-1 and exceeded the current WHO provisional guideline value of 10 mu g L-1 in more than 50% of the sampled wells. The WHO guideline of 250 mg L-1 for chloride and sulphate was also exceeded in more than a third of the samples, indicating high salinity in the drinking waters. Synthetic drinking water could be treated effectively by the IOCS- and CIM-based filters reducing As to concentrations lower than 10 mu g L-1. High levels of chloride and sulphate did not influence As removal efficiency. However, phosphate concentrations in the range from 4 to 24 mg L-1 drastically decreased removal efficiency of the IOCS-based filter but had no effects on removal efficiency of the CIM-based filter. Results of this study can be used as a base for further testing and practical implementation of drinking water purification in the Oruro region

    Identification of novel stress-responsive biomarkers from gene expression datasets in tomato roots

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    Published by CSIRO Publishing. This is the Author Accepted Manuscript. This article may be used for personal use only.Abiotic stresses such as heat, drought or salinity have been widely studied individually. Nevertheless, in the nature and in the field, plants and crops are commonly exposed to a different combination of stresses, which often result in a synergistic response mediated by the activation of several molecular pathways that cannot be inferred from the response to each individual stress. By screening microarray data obtained from different plant species and under different stresses, we identified several conserved stress-responsive genes whose expression was differentially regulated in tomato (Solanum lycopersicum L.) roots in response to one or several stresses. We validated 10 of these genes as reliable biomarkers whose expression levels are related to different signalling pathways involved in adaptive stress responses. In addition, the genes identified in this work could be used as general salt-stress biomarkers to rapidly evaluate the response of salt-tolerant cultivars and wild species for which sufficient genetic information is not yet available

    Comparison of Regional and Statewide Impacts on Salinity Mitigation in the Arkansas River Valley

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    The Arkansas River in Colorado has a major salinity problem, due to agricultural runoff caused by irrigation. It is necessary to see how on-farm net sales, regional and state employment and income levels are affected by alternative aquifer recharge rates. The positive impacts were greatest for the 40% recharge rate.Resource /Energy Economics and Policy,

    Remote Sensing For Water Resources And Hydrology. Recommended research emphasis for the 1980's

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    The problems and the areas of activity that the Panel believes should be emphasized in work on remote sensing for water resources and hydrology in the 1980's are set forth. The Panel deals only with those activities and problems in water resources and hydrology that the Panel considers important, and where, in the Panel's opinion, application of current remote sensing capability or advancements in remote sensing capability can help meet urgent problems and provide large returns in practical benefits

    The coastal environmental profile of Brunei Darussalam: resource assessment and management issues

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    Coastal zone management, Resource development, Coastal zone, Environmental profile, Brunei Darussalam, Resource /Energy Economics and Policy,

    The Economics of Desertification, Land Degradation, and Drought; Toward an Integrated Global Assessment

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    Land degradation has not been comprehensively addressed at the global level or in developing countries. A suitable economic framework that could guide investments and institutional action is lacking. This study aims to overcome this deficiency and to provide a framework for a global assessment based on a consideration of the costs of action versus inaction regarding desertification, land degradation, and drought (DLDD). Most of the studies on the costs of land degradation (mainly limited to soil erosion) give cost estimates of less than 1 percent up to about 10 percent of the agricultural gross domestic product (GDP) for various countries worldwide. But the indirect costs of DLDD on the economy (national income), as well as their socioeconomic consequences (particularly poverty impacts), must be accounted for, too. Despite the numerous challenges, a global assessment of the costs of action and inaction against DLDD is possible, urgent, and necessary. This study provides a framework for such a global assessment and provides insights from some related country studies.Agricultural Finance, Crop Production/Industries, Environmental Economics and Policy, Land Economics/Use, Resource /Energy Economics and Policy,
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