Current Status of the EMOO Repository, Including Current and Future Research Trends

In this talk, Ill present some statistics of the EMOO repository (delta.cs.cinvestav.mx/~ccoello/EMOO/), emphasizing some of the trends that have been detected in terms of basic research and applications of multi-objective evolutionary algorithms. For example, Ill discuss the remarkable increase in PhD theses related to EMOO, as well as the number of journal papers and exposure of the area in evolutionary computation conferences. Finally, some (potential) future research trends will also be discussed

04461 Abstracts Collection -- Practical Approaches to Multi-Objective Optimization

From 07.11.04 to 12.11.04, the Dagstuhl Seminar 04461 ``Practical Approaches to Multi-Objective Optimization\u27\u27 was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the seminar topics and goals in general. Links to extended abstracts or full papers are provided, if available

A multiple objective optimization approach to the decommissioning and dismantling of a nuclear power plant.

The complexity, relevance and critical nature of the decommissioning of nuclear power plants (NPP) are of great significance in today\u27s society. Following the catastrophe in Fukushima a shift in the general public\u27s perception of NPP took place throughout the world and in Europe in particular. In this dissertation interdisciplinary methods will be discussed to identify solutions which take into account the technological complexity and organizational issues involved in the dismantling and decommissioning process of NPP. Operations research, lean management, simultaneous engineering, cost analysis, multiple-objective optimization, project management, software tools are powerful concepts and methodologies when undertaking the dismantling and decommissioning process of NPP. Besides the presentation of a wide range of terminological and methodological definitions and technical terms based on the Literature Review, in the dissertation a framework for model development of a Multiple objective optimization problem (MOOP) will discussed focusing on empirical data from a virtual NPP. The theoretical foundation of the framework is at the intersection of two successful approaches used to describe and accomplish similar complex challenges, and the integration of state-of-the-art process approaches such as lean management. The procedural conception of the model is mainly leant on the OMEGA model (International Atomic Energy Agency (IAEA) (2008)). Mathematically the model is derived from Jones et. al. (1998). Finally the application of the model using different software tools (AIMMS, MATLAB, R and SPSS) will be presented. In conclusion the work will be put into a position to venture a critical outlook and discussion for the future of the decommissioning and dismantling processes of NPP. The main goal of this dissertation is to define the requirements for the optimization of three objectives: Minimizing the total project cost, reducing the safety hazard (risk) and managing project duration. Also a description of how the programming language R and the AIMMS program interfaces with the OMEGA application and how R will be used to solve the MOOP will be given. The software Microsoft Project will be leveraged in order to model this objective

A Comprehensive Review of Bio-Inspired Optimization Algorithms Including Applications in Microelectronics and Nanophotonics

The application of artificial intelligence in everyday life is becoming all-pervasive and unavoidable. Within that vast field, a special place belongs to biomimetic/bio-inspired algorithms for multiparameter optimization, which find their use in a large number of areas. Novel methods and advances are being published at an accelerated pace. Because of that, in spite of the fact that there are a lot of surveys and reviews in the field, they quickly become dated. Thus, it is of importance to keep pace with the current developments. In this review, we first consider a possible classification of bio-inspired multiparameter optimization methods because papers dedicated to that area are relatively scarce and often contradictory. We proceed by describing in some detail some more prominent approaches, as well as those most recently published. Finally, we consider the use of biomimetic algorithms in two related wide fields, namely microelectronics (including circuit design optimization) and nanophotonics (including inverse design of structures such as photonic crystals, nanoplasmonic configurations and metamaterials). We attempted to keep this broad survey self-contained so it can be of use not only to scholars in the related fields, but also to all those interested in the latest developments in this attractive area

Advances in Evolutionary Algorithms

With the recent trends towards massive data sets and significant computational power, combined with evolutionary algorithmic advances evolutionary computation is becoming much more relevant to practice. Aim of the book is to present recent improvements, innovative ideas and concepts in a part of a huge EA field

The hitler-youth in the third reich

This work attempts to answer, at least in part, two specific questions: why did the Hitler-Youth arise, and what was it? Any judgement which this paper offers as to why the Hitler-Youth arose by all rights should be questioned. Probably it is too soon to attempt such an analysis. But if attempts were never made, the criticism, which almost invariably results in further thinking and perhaps firmer conclusions would have no point at which to begin

Functional and structural genomics of amino acid metabolism in Streptomyces coelicolor

An investigation of amino acid metabolism in Streptomyces coelicolor, including the anabolism of tryptophan, histidine, the branched-chain amino acids and proline, as well as the catabolism of the latter, is reported. The experiments reported herein were conceptually conceived within a functional genomics framework. For this purpose the complete genome sequence of S. coelicolor was systematically exploited. Moreover, the current knowledge on the physiology of Streptomyces was taken onboard, as well as the prevailing and emerging notions on the evolution of proteins and metabolic pathways. Some of the results obtained using S. coelicolor as a model organism were expanded to other actinomycetes, such as Mycobacterium tuberculosis. This was aided by a comparative genomics analysis of the actinomycetes whose genomes have been sequenced. The theoretical principles that give support to this thesis are introduced in Chapter 1. This study was greatly facilitated by the development of a novel PCRtargeting mutagenesis method of which details can be found in Chapter VII. The discovery of a common isomerase for tryptophan and histidine biosynthesis is reported in Chapter II. This discovery arose from efforts aimed at reconstructing the tryptophan biosynthetic pathway of S. coelicolor, since the genome sequence project of this organism failed to identifiy a trpF gene coding for the enzyme phosphoribosyl anthranilate isomerase. The solution of this functional genomics discrepancy led to the discovery of a putative (~a)8-barrel enzyme, termed PriA, whose preliminary functional and structural characterisation is reported in Chapter III. The evolutionary implications of the discovery of PriA are discussed within Chapters III and N. A comparative genomics analysis of actinomycetes centred on the priA gene is presented in the latter Chapter, supporting the notion that this novel protein is spread across the high (0 + C) content Gram-positive organisms. Indeed, it was predicted that a priA orthologue accounts for the lack of a trpF gene from the genome of M tuberculosis, a hypothesis that proved to be correct. Finally, evidence to support the notion that the histidine and tryptophan biosynthetic pathways co-evolved is presented. In contrast to the isomerisation catalysed by PriA, in which an enzyme is shared by two amino acid biosynthetic pathways, several paralogous enzymes with the potential to account for the first step of tryptophan biosynthesis from chorismate were found on the genome of S. coelicolor. These chorismate-utilising enzymes are investigated in Chapter V. Mutational analysis of some of this paralogues is reported and it is anticipated that the analysis and results reported therein will serve to direct future experiments aimed at identifying the trpE paralogue encoding the enzyme anthranilate synthase. Chapter VI reports on the identification of the proC gene involved in the last step of proline biosynthesis in S. coelicolor. The pyrroline-5-carboxylate reductase activity of the enzyme encoded by the putative proC gene was extensively characterised, with particular emphasis on the interaction between primary and secondary metabolism. Furthermore, mutational analysis of proC suggested that paralogues of this gene are present on the genome of this organism, since its deletion did not lead to an auxotrophic phenotype. Investigation of this observation showed that two paralogous enzymes encoded by i1vC-like genes, involved in biosynthesis of the branched-chain amino acids, are capable of compensating for the lack of proC. This is the first example of a physiological link between the biosynthesis of proline and the branched-chain amino acids. To sum up, the results reported in this thesis represent an advancement towards understanding the physiology of S. coelicolor as a model actinomycete, within a functional and structural genomics framework. They also offer evidence on the evolutionary principles that lead to the appearance of novel proteins and metabolic pathways in bacteria.EThOS - Electronic Theses Online ServiceGBUnited Kingdo