The cost and cost-effectiveness of alternative strategies to expand treatment to HIV-positive South Africans: scale economies and outreach costs

This repository item contains a single issue of the Health and Development Discussion Papers, an informal working paper series that began publishing in 2002 by the Boston University Center for Global Health and Development. It is intended to help the Center and individual authors to disseminate work that is being prepared for journal publication or that is not appropriate for journal publication but might still have value to readers.The South African government is currently discussing various alternative approaches to the further expansion of antiretroviral treatment (ART) in public-sector facilities. We used the EMOD-HIV model, a HIV transmission model which projects South African HIV incidence and prevalence and ARV treatment by age-group for alternative combinations of treatment eligibility criteria and testing, to generate 12 epidemiological scenarios. Using data from our own bottom-up cost analyses in South Africa, we separate outpatient cost into nonscale- dependent costs (drugs and laboratory tests) and scale-dependent cost (staff, space, equipment and overheads) and model the cost of production according to the expected future number and size of clinics. On the demand side, we include the cost of creating and sustaining the projected incremental demand for testing and treatment. Previous research with EMOD-HIV has shown that more vigorous recruitment of patients with CD4 counts less than 350 is an advantageous policy over a five-year horizon. Over 20 years, however, the model assumption that a person on treatment is 92% less infectious improves the cost-effectiveness of higher eligibility thresholds, averting HIV infections for between $1,700 and$2,800, while more vigorous expansion under the current guidelines would cost more than $7,500 per incremental HIV infection averted. Based on analysis of the sensitivity of the results to 1,728 alternative parameter combinations at each of four discount rates, we conclude that better knowledge of the behavioral elasticities could reduce the uncertainty of cost estimates by a factor of 4 to 10

Power consumption modeling in optical multilayer networks

The evaluation of and reduction in energy consumption of backbone telecommunication networks has been a popular subject of academic research for the last decade. A critical parameter in these studies is the power consumption of the individual network devices. It appears that across different studies, a wide range of power values for similar equipment is used. This is a result of the scattered and limited availability of power values for optical multilayer network equipment. We propose reference power consumption values for Internet protocol/multiprotocol label switching, Ethernet, optical transport networking and wavelength division multiplexing equipment. In addition we present a simplified analytical power consumption model that can be used for large networks where simulation is computationally expensive or unfeasible. For illustration and evaluation purpose, we apply both calculation approaches to a case study, which includes an optical bypass scenario. Our results show that the analytical model approximates the simulation result to over 90% or higher and that optical bypass potentially can save up to 50% of power over a non-bypass scenario

Video distribution system cost model

A cost model that can be used to systematically identify the costs of procuring and operating satellite linked communications systems is described. The user defines a network configuration by specifying the location of each participating site, the interconnection requirements, and the transmission paths available for the uplink (studio to satellite), downlink (satellite to audience), and voice talkback (between audience and studio) segments of the network. The model uses this information to calculate the least expensive signal distribution path for each participating site. Cost estimates are broken downy by capital, installation, lease, operations and maintenance. The design of the model permits flexibility in specifying network and cost structure

The ARKO labour-cost model

Beschrijving van het herziene EIM-Arbeidskostenmodel. De herziening was noodzakelijk door de drastische aanpassingen in het socialezekerheidsstelsel in de afgelopen jaren. Met het model is het mogelijk inzicht te verschaffen in de ontwikkeling van de afzonderlijke elementen van de loonkosten naar sector en grootteklasse op de korte termijn. Ook is het mogelijk de effecten op de loonkosten van beleidsmaatregelen in de socialezekerheidssfeer door te rekenen (naar grootteklasse en sector). Ook de ontwikkeling van de loonkosten in de jaren negentig komt aan de orde, waarbij de aandacht is toegespitst op de werkgeverswig.

An Invariant Cost Model for the Lambda Calculus

We define a new cost model for the call-by-value lambda-calculus satisfying the invariance thesis. That is, under the proposed cost model, Turing machines and the call-by-value lambda-calculus can simulate each other within a polynomial time overhead. The model only relies on combinatorial properties of usual beta-reduction, without any reference to a specific machine or evaluator. In particular, the cost of a single beta reduction is proportional to the difference between the size of the redex and the size of the reduct. In this way, the total cost of normalizing a lambda term will take into account the size of all intermediate results (as well as the number of steps to normal form).Comment: 19 page

Estimating Travel Cost Model: Spatial Approach

travel cost model, spatial analysis, Environmental Economics and Policy,

Cost Model-Driven Test Resource Partitioning for SoCs

The increasing complexity of modern SoCs and quality expectations are making the cost of test represent an significant fraction of the manufacturing cost. The main factors contributing to the cost of test are the required number of tester pins, the test application time, the tester memory requirements and the area overhead required by the test resources. These factors contribute with different weights, depending on the cost model of each product. Several methods have been proposed to optimize each of these factors, however none of them allows an objective function derived from the actual cost model of each product. In this paper, we propose a cost model-driven test resource allocation and scheduling method that minimizes the cost of test

Comparison Analysis of Cost Model and Revaluation Model Method on Fixed Assets Measurement and Its Impacts on Financial Report (Study on PT Mulia Industrindo Tbk)

This research aims to analyze the comparison of fixed assets measurement using cost model and revaluation model on PT Mulia Industrindo Tbk and also to know the impacts on company\u27s financial reports. Research method used in this study is comparative descriptive qualitative by comparing fixed assets measurement using cost model and revaluation model. Research object is PT Mulia Industrindo Tbk, especially the financial report for the year of 2008 until 2012. This research uses secondary data in the form of research object\u27s financial reports. Result of this research indicates that the implementation of revaluation model has some impacts to company\u27s financial reports because it increases the value of assets and equity, decreases gross income, increases equity\u27s value on company\u27s equity report, has positive and negative impacts on financial ratios, and also increases the amount of assets deferred tax and liabilities deferred tax