Individual Microscopic Results Of Bottleneck Experiments

This contribution provides microscopic experimental study of pedestrian motion in front of the bottleneck, explains the high variance of individual travel time by the statistical analysis of trajectories. The analysis shows that this heterogeneity increases with increasing occupancy. Some participants were able to reach lower travel time due more efficient path selection and more aggressive behavior within the crowd. Based on this observations, linear model predicting travel time with respect to the aggressiveness of pedestrian is proposed.Comment: Submitted to Traffic and Granullar Flow 2015, Springe

DEVELOPMENT OF A MIXED-FLOW OPTIMIZATION SYSTEM FOR EMERGENCY EVACUATION IN URBAN NETWORKS

In most metropolitan areas, an emergency evacuation may demand a potentially large number of evacuees to use transit systems or to walk over some distance to access their passenger cars. In the process of approaching designated pick-up points for evacuation, the massive number of pedestrians often incurs tremendous burden to vehicles in the roadway network. Hence, one critical issue in a multi-modal evacuation planning is the effective coordination of the vehicle and pedestrian flows by considering their complex interactions. The purpose of this research is to develop an integrated system that is capable of generating the optimal evacuation plan and reflecting the real-world network traffic conditions caused by the conflicts of these two types of flows. The first part of this research is an integer programming model designed to optimize the control plans for massive mixed pedestrian-vehicle flows within the evacuation zone. The proposed model, integrating the pedestrian and vehicle networks, can effectively account for their potential conflicts during the evacuation. The model can generate the optimal routing strategies to guide evacuees moving toward either their pick-up locations or parking areas and can also produce a responsive plan to accommodate the massive pedestrian movements. The second part of this research is a mixed-flow simulation tool that can capture the conflicts between pedestrians, between vehicles, and between pedestrians and vehicles in an evacuation network. The core logic of this simulation model is the Mixed-Cellular Automata (MCA) concept, which, with some embedded components, offers a realistic mechanism to reflect the competing and conflicting interactions between vehicle and pedestrian flows. This study is expected to yield the following contributions * Design of an effective framework for planning a multi-modal evacuation within metropolitan areas; * Development of an integrated mixed-flow optimization model that can overcome various modeling and computing difficulties in capturing the mixed-flow dynamics in urban network evacuation; * Construction and calibration of a new mixed-flow simulation model, based on the Cellular Automaton concept, to reflect various conflicting patterns between vehicle and pedestrian flows in an evacuation network

Transport Layer solution for bulk data transfers over Heterogeneous Long Fat Networks in Next Generation Networks

Aquesta tesi per compendi centra les seves contribucions en l'aprenentatge i innovació de les Xarxes de Nova Generació. És per això que es proposen diferents contribucions en diferents àmbits (Smart Cities, Smart Grids, Smart Campus, Smart Learning, Mitjana, eHealth, Indústria 4.0 entre d'altres) mitjançant l'aplicació i combinació de diferents disciplines (Internet of Things, Building Information Modeling, Cloud Storage, Ciberseguretat, Big Data, Internet de el Futur, Transformació Digital). Concretament, es detalla el monitoratge sostenible del confort a l'Smart Campus, la que potser es la meva aportació més representativa dins de la conceptualització de Xarxes de Nova Generació. Dins d'aquest innovador concepte de monitorització s'integren diferents disciplines, per poder oferir informació sobre el nivell de confort de les persones. Aquesta investigació demostra el llarg recorregut que hi ha en la transformació digital dels sectors tradicionals i les NGNs. Durant aquest llarg aprenentatge sobre les NGN a través de les diferents investigacions, es va poder observar una problemàtica que afectava de manera transversal als diferents camps d'aplicació de les NGNs i que aquesta podia tenir una afectació en aquests sectors. Aquesta problemàtica consisteix en el baix rendiment durant l'intercanvi de grans volums de dades sobre xarxes amb gran capacitat d'ample de banda i remotament separades geogràficament, conegudes com a xarxes elefant. Concretament, això afecta al cas d'ús d'intercanvi massiu de dades entre regions Cloud (Cloud Data Sharing use case). És per això que es va estudiar aquest cas d'ús i les diferents alternatives a nivell de protocols de transport,. S'estudien les diferents problemàtiques que pateixen els protocols i s'observa per què aquests no són capaços d'arribar a rendiments òptims. Deguda a aquesta situació, s'hipotetiza que la introducció de mecanismes que analitzen les mètriques de la xarxa i que exploten eficientment la capacitat de la mateixa milloren el rendiment dels protocols de transport sobre xarxes elefant heterogènies durant l'enviament massiu de dades. Primerament, es dissenya l’Adaptative and Aggressive Transport Protocol (AATP), un protocol de transport adaptatiu i eficient amb l'objectiu de millorar el rendiment sobre aquest tipus de xarxes elefant. El protocol AATP s'implementa i es prova en un simulador de xarxes i un testbed sota diferents situacions i condicions per la seva validació. Implementat i provat amb èxit el protocol AATP, es decideix millorar el propi protocol, Enhanced-AATP, sobre xarxes elefant heterogènies. Per això, es dissenya un mecanisme basat en el Jitter Ràtio que permet fer aquesta diferenciació. A més, per tal de millorar el comportament del protocol, s’adapta el seu sistema de fairness per al repartiment just dels recursos amb altres fluxos Enhanced-AATP. Aquesta evolució s'implementa en el simulador de xarxes i es realitzen una sèrie de proves. A l'acabar aquesta tesi, es conclou que les Xarxes de Nova Generació tenen molt recorregut i moltes coses a millorar causa de la transformació digital de la societat i de l'aparició de nova tecnologia disruptiva. A més, es confirma que la introducció de mecanismes específics en la concepció i operació dels protocols de transport millora el rendiment d'aquests sobre xarxes elefant heterogènies.Esta tesis por compendio centra sus contribuciones en el aprendizaje e innovación de las Redes de Nueva Generación. Es por ello que se proponen distintas contribuciones en diferentes ámbitos (Smart Cities, Smart Grids, Smart Campus, Smart Learning, Media, eHealth, Industria 4.0 entre otros) mediante la aplicación y combinación de diferentes disciplinas (Internet of Things, Building Information Modeling, Cloud Storage, Ciberseguridad, Big Data, Internet del Futuro, Transformación Digital). Concretamente, se detalla la monitorización sostenible del confort en el Smart Campus, la que se podría considerar mi aportación más representativa dentro de la conceptualización de Redes de Nueva Generación. Dentro de este innovador concepto de monitorización se integran diferentes disciplinas, para poder ofrecer información sobre el nivel de confort de las personas. Esta investigación demuestra el recorrido que existe en la transformación digital de los sectores tradicionales y las NGNs. Durante este largo aprendizaje sobre las NGN a través de las diferentes investigaciones, se pudo observar una problemática que afectaba de manera transversal a los diferentes campos de aplicación de las NGNs y que ésta podía tener una afectación en estos sectores. Esta problemática consiste en el bajo rendimiento durante el intercambio de grandes volúmenes de datos sobre redes con gran capacidad de ancho de banda y remotamente separadas geográficamente, conocidas como redes elefante, o Long Fat Networks (LFNs). Concretamente, esto afecta al caso de uso de intercambio de datos entre regiones Cloud (Cloud Data Data use case). Es por ello que se estudió este caso de uso y las diferentes alternativas a nivel de protocolos de transporte. Se estudian las diferentes problemáticas que sufren los protocolos y se observa por qué no son capaces de alcanzar rendimientos óptimos. Debida a esta situación, se hipotetiza que la introducción de mecanismos que analizan las métricas de la red y que explotan eficientemente la capacidad de la misma mejoran el rendimiento de los protocolos de transporte sobre redes elefante heterogéneas durante el envío masivo de datos. Primeramente, se diseña el Adaptative and Aggressive Transport Protocol (AATP), un protocolo de transporte adaptativo y eficiente con el objetivo maximizar el rendimiento sobre este tipo de redes elefante. El protocolo AATP se implementa y se prueba en un simulador de redes y un testbed bajo diferentes situaciones y condiciones para su validación. Implementado y probado con éxito el protocolo AATP, se decide mejorar el propio protocolo, Enhanced-AATP, sobre redes elefante heterogéneas. Además, con tal de mejorar el comportamiento del protocolo, se mejora su sistema de fairness para el reparto justo de los recursos con otros flujos Enhanced-AATP. Esta evolución se implementa en el simulador de redes y se realizan una serie de pruebas. Al finalizar esta tesis, se concluye que las Redes de Nueva Generación tienen mucho recorrido y muchas cosas a mejorar debido a la transformación digital de la sociedad y a la aparición de nueva tecnología disruptiva. Se confirma que la introducción de mecanismos específicos en la concepción y operación de los protocolos de transporte mejora el rendimiento de estos sobre redes elefante heterogéneas.This compendium thesis focuses its contributions on the learning and innovation of the New Generation Networks. That is why different contributions are proposed in different areas (Smart Cities, Smart Grids, Smart Campus, Smart Learning, Media, eHealth, Industry 4.0, among others) through the application and combination of different disciplines (Internet of Things, Building Information Modeling, Cloud Storage, Cybersecurity, Big Data, Future Internet, Digital Transformation). Specifically, the sustainable comfort monitoring in the Smart Campus is detailed, which can be considered my most representative contribution within the conceptualization of New Generation Networks. Within this innovative monitoring concept, different disciplines are integrated in order to offer information on people's comfort levels. . This research demonstrates the long journey that exists in the digital transformation of traditional sectors and New Generation Networks. During this long learning about the NGNs through the different investigations, it was possible to observe a problematic that affected the different application fields of the NGNs in a transversal way and that, depending on the service and its requirements, it could have a critical impact on any of these sectors. This issue consists of a low performance operation during the exchange of large volumes of data on networks with high bandwidth capacity and remotely geographically separated, also known as Elephant networks, or Long Fat Networks (LFNs). Specifically, this critically affects the Cloud Data Sharing use case. That is why this use case and the different alternatives at the transport protocol level were studied. For this reason, the performance and operation problems suffered by layer 4 protocols are studied and it is observed why these traditional protocols are not capable of achieving optimal performance. Due to this situation, it is hypothesized that the introduction of mechanisms that analyze network metrics and efficiently exploit network’s capacity meliorates the performance of Transport Layer protocols over Heterogeneous Long Fat Networks during bulk data transfers. First, the Adaptive and Aggressive Transport Protocol (AATP) is designed. An adaptive and efficient transport protocol with the aim of maximizing its performance over this type of elephant network.. The AATP protocol is implemented and tested in a network simulator and a testbed under different situations and conditions for its validation. Once the AATP protocol was designed, implemented and tested successfully, it was decided to improve the protocol itself, Enhanced-AATP, to improve its performance over heterogeneous elephant networks. In addition, in order to upgrade the behavior of the protocol, its fairness system is improved for the fair distribution of resources among other Enhanced-AATP flows. Finally, this evolution is implemented in the network simulator and a set of tests are carried out. At the end of this thesis, it is concluded that the New Generation Networks have a long way to go and many things to improve due to the digital transformation of society and the appearance of brand-new disruptive technology. Furthermore, it is confirmed that the introduction of specific mechanisms in the conception and operation of transport protocols improves their performance on Heterogeneous Long Fat Networks

Assessment, Diagnosis and Service Life Prediction

Service life prediction is crucial for the adoption of more sustainable solutions, allowing developers to optimize the costs and environmental impact of buildings during their life cycle. An accurate assessment of the service life of buildings requires a thorough understanding of the degradation mechanisms and behaviour of the construction materials. Building pathology assessment methods characterize the deterioration state of buildings, using specific measurable properties as indicators. Based on this information, different service life prediction methodologies can be defined to provide reliable data concerning the most probable failure time of whole buildings and individual components according to their characteristics and their age. This Special Issue provides new perspectives on the existing knowledge related with various aspects of the Assessment, Diagnosis and Service Life Prediction of buildings and their components. The ten original research studies published in this Special Issue result from research centres and university departments of Civil and Construction Engineering, Safety Management, Environmental Engineering, Geotechnical Engineering, and Architecture and the Built Environment, with relevant contributions from experts from Australia, Brazil, the Czech Republic, Hong Kong, Iran, Israel, Norway, Portugal, and Taiwan. The studies included in this Special Issue address topics related to: Building pathology assessment methods; Diagnosis of defects in buildings and components; Appropriate intervention and repair techniques; Deterministic and stochastic service life prediction models

Discovery of orexant and anorexant agents with indazole scaffold endowed with peripheral antiedema activity

CB1 receptors and endocannabinoids are integrated components of neuronal networks controlling different organism’s functions, such as appetite and food intake in the hypothalamus. A series of Rimonabant/Fubinaca hybrids have been synthesized in solution as C-terminal amides, acids, methyl esters and N-methyl amides. These compounds have been studied in cannabinoid receptor binding assay and functional receptor assay in vitro, the most active among them as agonist (LONI 11) and antagonist (LONI 4) were tested in vivo to evaluate their ability to stimulate or suppress the feeding behavior after i.p. administration. For LONI 11 formalin test and tail flick tests after s.c. and i.c.v. routes respectively, were also performed in vivo with the aim to investigate the antinociceptive effect at the central or peripheral level. In the Zymosan-induced edema and hyperalgesia, LONI 11 reduced the % paw volume increase and % paw latency after s.c. administration, also suggesting a potential anti-inflammatory activity at the periphery. Keywords. Cannabinoid receptor, Rimonabant, food intake, anorexant agent, edema

THE STANCE LOGISTICS: An Attempt to Adapt Logistics Principles on Human and Inter-human Movement Behaviors

The broad span of Logistics Management encompasses control of time, place, movement, energy (efforts, labor), as well as the positioning, stance and movement of products, materials, commodities, and people. This study coins the term Stance Logistics to focus on the stance and movement of people within the range of Logistics principles. The philosophy behind this is to enhance the required sensitivity with respect to management and control of time, place, movement, motion, stance and energy in material and nonmaterial exchanges and in all types of human encounters. Stance Logistics includes not only the “on foot” (pedestrian) or “in-vehicle” (automated) movements and public behaviour in stopping, standing, and positioning, but also individual predisposition of physical and mental response, and awareness (aesthesia). This essay describes the application of the scientific principles of Logistics to the personal experiences of people. Current Logistics literature includes mostly models developed on pedestrian and evacuation movement behaviour. To the author’s knowledge, however, there is nothing documented on the issue of personal individual Logistics Stance. Behaviours, especially that of blocking other people’s ways and passages, intervening, rudeness and queue-jumping in various environmental settings have not been extensively studied, if at all, whether during walking, pausing, stopping, face-to-face encounters, standing or waiting in lines and lanes or waiting for an elevator or metro train door to open. This study seeks underlying clues to increase sensitivity and awareness of people’s movement particularly in public areas by shedding light on Logistics behaviours of people. When combined with applicable models of pedestrian movements and integrated with the general principles of Logistics, Stance Logistics can serve as an important guide to facilitate the daily activities of many people. It is believed that, this exploratory study will pave the way for further research to produce promising results on the aspects of this new concept of Stance Logistic

MODELLING VIRTUAL ENVIRONMENT FOR ADVANCED NAVAL SIMULATION

This thesis proposes a new virtual simulation environment designed as element of an interoperable federation of simulator to support the investigation of complex scenarios over the Extended Maritime Framework (EMF). Extended Maritime Framework is six spaces environment (Underwater, Water surface, Ground, Air, Space, and Cyberspace) where parties involved in Joint Naval Operations act. The amount of unmanned vehicles involved in the simulation arise the importance of the Communication modelling, thus the relevance of Cyberspace. The research is applied to complex cases (one applied to deep waters and one to coast and littoral protection) as examples to validate this approach; these cases involve different kind of traditional assets (e.g. satellites, helicopters, ships, submarines, underwater sensor infrastructure, etc.) interact dynamically and collaborate with new autonomous systems (i.e. AUV, Gliders, USV and UAV). The use of virtual simulation is devoted to support validation of new concepts and investigation of collaborative engineering solutions by providing a virtual representation of the current situation; this approach support the creation of dynamic interoperable immersive framework that could support training for Man in the Loop, education and tactical decision introducing the Man on the Loop concepts. The research and development of the Autonomous Underwater Vehicles requires continuous testing so a time effective approach can result a very useful tool. In this context the simulation can be useful to better understand the behaviour of Unmanned Vehicles and to avoid useless experimentations and their costs finding problems before doing them. This research project proposes the creation of a virtual environment with the aim to see and understand a Joint Naval Scenario. The study will be focusing especially on the integration of Autonomous Systems with traditional assets; the proposed simulation deals especially with collaborative operation involving different types of Autonomous Underwater Vehicles (AUV), Unmanned Surface Vehicles (USV) and UAV (Unmanned Aerial Vehicle). The author develops an interoperable virtual simulation devoted to present the overall situation for supervision considering also the sensor capabilities, communications and mission effectiveness that results dependent of the different asset interaction over a complex heterogeneous network. The aim of this research is to develop a flexible virtual simulation solution as crucial element of an HLA federation able to address the complexity of Extended Maritime Framework (EMF). Indeed this new generation of marine interoperable simulation is a strategic advantage for investigating the problems related to the operational use of autonomous systems and to finding new ways to use them respect to different scenarios. The research deal with the creation of two scenarios, one related to military operations and another one on coastal and littoral protection where the virtual simulation propose the overall situation and allows to navigate into the virtual world considering the complex physics affecting movement, perception, interaction and communication. By this approach, it becomes evident the capability to identify, by experimental analysis within the virtual world, the new solutions in terms of engineering and technological configuration of the different systems and vehicles as well as new operational models and tactics to address the specific mission environment. The case of study is a maritime scenario with a representation of heterogeneous network frameworks that involves multiple vehicles both naval and aerial including AUVs, USVs, gliders, helicopter, ships, submarines, satellite, buoys and sensors. For the sake of clarity aerial communications will be represented divided from underwater ones. A connection point for the latter will be set on the keel line of surface vessels representing communication happening via acoustic modem. To represent limits in underwater communications, underwater signals have been considerably slowed down in order to have a more realistic comparison with aerial ones. A maximum communication distance is set, beyond which no communication can take place. To ensure interoperability the HLA Standard (IEEE 1516 evolved) is adopted to federate other simulators so to allow its extensibility for other case studies. Two different scenarios are modelled in 3D visualization: Open Water and Port Protection. The first one aims to simulate interactions between traditional assets in Extended Maritime Framework (EMF) such as satellite, navy ships, submarines, NATO Research Vessels (NRVs), helicopters, with new generation unmanned assets as AUV, Gliders, UAV, USV and the mutual advantage the subjects involved in the scenario can have; in other word, the increase in persistence, interoperability and efficacy. The second scenario models the behaviour of unmanned assets, an AUV and an USV, patrolling a harbour to find possible threats. This aims to develop an algorithm to lead patrolling path toward an optimum, guaranteeing a high probability of success in the safest way reducing human involvement in the scenario. End users of the simulation face a graphical 3D representation of the scenario where assets would be represented. He can moves in the scenario through a Free Camera in Graphic User Interface (GUI) configured to entitle users to move around the scene and observe the 3D sea scenario. In this way, players are able to move freely in the synthetic environment in order to choose the best perspective of the scene. The work is intended to provide a valid tool to evaluate the defencelessness of on-shore and offshore critical infrastructures that could includes the use of new technologies to take care of security best and preserve themselves against disasters both on economical and environmental ones