341 research outputs found

    Compressing DNA sequence databases with coil

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    Background: Publicly available DNA sequence databases such as GenBank are large, and are growing at an exponential rate. The sheer volume of data being dealt with presents serious storage and data communications problems. Currently, sequence data is usually kept in large "flat files," which are then compressed using standard Lempel-Ziv (gzip) compression – an approach which rarely achieves good compression ratios. While much research has been done on compressing individual DNA sequences, surprisingly little has focused on the compression of entire databases of such sequences. In this study we introduce the sequence database compression software coil. Results: We have designed and implemented a portable software package, coil, for compressing and decompressing DNA sequence databases based on the idea of edit-tree coding. coil is geared towards achieving high compression ratios at the expense of execution time and memory usage during compression – the compression time represents a "one-off investment" whose cost is quickly amortised if the resulting compressed file is transmitted many times. Decompression requires little memory and is extremely fast. We demonstrate a 5% improvement in compression ratio over state-of-the-art general-purpose compression tools for a large GenBank database file containing Expressed Sequence Tag (EST) data. Finally, coil can efficiently encode incremental additions to a sequence database. Conclusion: coil presents a compelling alternative to conventional compression of flat files for the storage and distribution of DNA sequence databases having a narrow distribution of sequence lengths, such as EST data. Increasing compression levels for databases having a wide distribution of sequence lengths is a direction for future work

    Digital Image Access & Retrieval

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    The 33th Annual Clinic on Library Applications of Data Processing, held at the University of Illinois at Urbana-Champaign in March of 1996, addressed the theme of "Digital Image Access & Retrieval." The papers from this conference cover a wide range of topics concerning digital imaging technology for visual resource collections. Papers covered three general areas: (1) systems, planning, and implementation; (2) automatic and semi-automatic indexing; and (3) preservation with the bulk of the conference focusing on indexing and retrieval.published or submitted for publicatio

    COSPO/CENDI Industry Day Conference

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    The conference's objective was to provide a forum where government information managers and industry information technology experts could have an open exchange and discuss their respective needs and compare them to the available, or soon to be available, solutions. Technical summaries and points of contact are provided for the following sessions: secure products, protocols, and encryption; information providers; electronic document management and publishing; information indexing, discovery, and retrieval (IIDR); automated language translators; IIDR - natural language capabilities; IIDR - advanced technologies; IIDR - distributed heterogeneous and large database support; and communications - speed, bandwidth, and wireless

    Column Imprints: A Secondary Index Structure

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    Large scale data warehouses rely heavily on secondary indexes, such as bitmaps and b-trees, to limit access to slow IO devices. However, with the advent of large main memory systems, cache conscious secondary indexes are needed to improve also the transfer bandwidth between memory and cpu. In this paper, we introduce column imprint, a simple but efficient cache conscious secondary index. A column imprint is a collection of many small bit vectors, each indexing the data points of a single cacheline. An imprint is used during query evaluation to limit data access and thus minimize memory traffic. The compression for imprints is cpu friendly and exploits the empirical observation that data often exhibits local clustering or partial ordering as a side-effect of the construction process. Most importantly, column imprint compression remains effective and robust even in the case of unclustered data, while other state-of-the-art solutions fail. We conducted an extensive experimental evaluation to assess the applicability and the performance impact of the column imprints. The storage overhead, when experimenting with real world datasets, is just a few percent over the size of the columns being indexed. The evaluation time for over 40000 range queries of varying selectivity revealed the efficiency of the proposed index compar
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