P4CEP: Towards In-Network Complex Event Processing

In-network computing using programmable networking hardware is a strong trend in networking that promises to reduce latency and consumption of server resources through offloading to network elements (programmable switches and smart NICs). In particular, the data plane programming language P4 together with powerful P4 networking hardware has spawned projects offloading services into the network, e.g., consensus services or caching services. In this paper, we present a novel case for in-network computing, namely, Complex Event Processing (CEP). CEP processes streams of basic events, e.g., stemming from networked sensors, into meaningful complex events. Traditionally, CEP processing has been performed on servers or overlay networks. However, we argue in this paper that CEP is a good candidate for in-network computing along the communication path avoiding detouring streams to distant servers to minimize communication latency while also exploiting processing capabilities of novel networking hardware. We show that it is feasible to express CEP operations in P4 and also present a tool to compile CEP operations, formulated in our P4CEP rule specification language, to P4 code. Moreover, we identify challenges and problems that we have encountered to show future research directions for implementing full-fledged in-network CEP systems.Comment: 6 pages. Author's versio

Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in <i>C. elegans</i>

Parkinson's disease (PD), the second most prevalent neurodegenerative disease after Alzheimer's disease, is linked to the gradual loss of dopaminergic neurons in the substantia nigra. Disease loci causing hereditary forms of PD are known, but most cases are attributable to a combination of genetic and environmental risk factors. Increased incidence of PD is associated with rural living and pesticide exposure, and dopaminergic neurodegeneration can be triggered by neurotoxins such as 6-hydroxydopamine (6-OHDA). In C. elegans, this drug is taken up by the presynaptic dopamine reuptake transporter (DAT-1) and causes selective death of the eight dopaminergic neurons of the adult hermaphrodite. Using a forward genetic approach to find genes that protect against 6-OHDA-mediated neurodegeneration, we identified tsp-17, which encodes a member of the tetraspanin family of membrane proteins. We show that TSP-17 is expressed in dopaminergic neurons and provide genetic, pharmacological and biochemical evidence that it inhibits DAT-1, thus leading to increased 6-OHDA uptake in tsp-17 loss-of-function mutants. TSP-17 also protects against toxicity conferred by excessive intracellular dopamine. We provide genetic and biochemical evidence that TSP-17 acts partly via the DOP-2 dopamine receptor to negatively regulate DAT-1. tsp-17 mutants also have subtle behavioral phenotypes, some of which are conferred by aberrant dopamine signaling. Incubating mutant worms in liquid medium leads to swimming-induced paralysis. In the L1 larval stage, this phenotype is linked to lethality and cannot be rescued by a dop-3 null mutant. In contrast, mild paralysis occurring in the L4 larval stage is suppressed by dop-3, suggesting defects in dopaminergic signaling. In summary, we show that TSP-17 protects against neurodegeneration and has a role in modulating behaviors linked to dopamine signaling

Pacific Gas and Electric Company 2021 nuclear decommissioning cost triennial proceeding rebuttal testimony (Public Version)

Documented Testimony Author N/

Pacific Gas and Electric Company 2021 nuclear decommissioning cost triennial proceeding rebuttal testimony (Public Version)

Documented Testimony Author N/

Ageing at home with the help of information and communication technologies

Due to the ageing of the population, developed countries are facing increasing financial needs to provide suitable healthcare, social care and housing for the elderly. One of the ways in which society has responded to such issues is the idea that the elderly should be able to remain in their home environment as long as possible, where they would be capable of leading their lives as independently as possible with the best possible quality of life. This article is based on the assumption that the concept of ageing at home can be implemented with the help of information and communication technologies, which is why developed societies should integrate it into their regular healthcare and social welfare systems as soon as possible. The implementation process has proven to be very complex and as such requires careful planning, especially in Slovenia

Towards adaptive quality-aware Complex Event Processing in the Internet of Things

This paper investigates how to complement Complex Event Processing (CEP) with dynamic quality monitoring mechanisms and support the dynamic integration of suitable sensory data sources. In the proposed approach, queries to detect complex events are annotated with consumer-definable quality policies that are evaluated and used to autonomously assign (or even configure) suitable data sources of the sensing infrastructure. We present and study different forms of expressing quality policies and explore how they affect the process of quality monitoring including different modes of assessing and applying quality-related adaptations. A performance study in an IoT scenario shows that the proposed mechanisms in supporting quality policy monitoring and adaptively selecting suitable data sources succeed in enhancing the acquired quality of results while fulfilling consumers’ quality requirements. We show that the quality-based selection of sensor sources also extends the network’s lifetime by optimizing the data sources’ energy consumption