Barcode Annotations for Medical Image Retrieval: A Preliminary Investigation

This paper proposes to generate and to use barcodes to annotate medical images and/or their regions of interest such as organs, tumors and tissue types. A multitude of efficient feature-based image retrieval methods already exist that can assign a query image to a certain image class. Visual annotations may help to increase the retrieval accuracy if combined with existing feature-based classification paradigms. Whereas with annotations we usually mean textual descriptions, in this paper barcode annotations are proposed. In particular, Radon barcodes (RBC) are introduced. As well, local binary patterns (LBP) and local Radon binary patterns (LRBP) are implemented as barcodes. The IRMA x-ray dataset with 12,677 training images and 1,733 test images is used to verify how barcodes could facilitate image retrieval.Comment: To be published in proceedings of The IEEE International Conference on Image Processing (ICIP 2015), September 27-30, 2015, Quebec City, Canad

A graph-based approach for the retrieval of multi-modality medical images

Medical imaging has revolutionised modern medicine and is now an integral aspect of diagnosis and patient monitoring. The development of new imaging devices for a wide variety of clinical cases has spurred an increase in the data volume acquired in hospitals. These large data collections offer opportunities for search-based applications in evidence-based diagnosis, education, and biomedical research. However, conventional search methods that operate upon manual annotations are not feasible for this data volume. Content-based image retrieval (CBIR) is an image search technique that uses automatically derived visual features as search criteria and has demonstrable clinical benefits. However, very few studies have investigated the CBIR of multi-modality medical images, which are making a monumental impact in healthcare, e.g., combined positron emission tomography and computed tomography (PET-CT) for cancer diagnosis. In this thesis, we propose a new graph-based method for the CBIR of multi-modality medical images. We derive a graph representation that emphasises the spatial relationships between modalities by structurally constraining the graph based on image features, e.g., spatial proximity of tumours and organs. We also introduce a graph similarity calculation algorithm that prioritises the relationships between tumours and related organs. To enable effective human interpretation of retrieved multi-modality images, we also present a user interface that displays graph abstractions alongside complex multi-modality images. Our results demonstrated that our method achieved a high precision when retrieving images on the basis of tumour location within organs. The evaluation of our proposed UI design by user surveys revealed that it improved the ability of users to interpret and understand the similarity between retrieved PET-CT images. The work in this thesis advances the state-of-the-art by enabling a novel approach for the retrieval of multi-modality medical images

Human-Centered Content-Based Image Retrieval

Retrieval of images that lack a (suitable) annotations cannot be achieved through (traditional) Information Retrieval (IR) techniques. Access through such collections can be achieved through the application of computer vision techniques on the IR problem, which is baptized Content-Based Image Retrieval (CBIR). In contrast with most purely technological approaches, the thesis Human-Centered Content-Based Image Retrieval approaches the problem from a human/user centered perspective. Psychophysical experiments were conducted in which people were asked to categorize colors. The data gathered from these experiments was fed to a Fast Exact Euclidean Distance (FEED) transform (Schouten & Van den Broek, 2004), which enabled the segmentation of color space based on human perception (Van den Broek et al., 2008). This unique color space segementation was exploited for texture analysis and image segmentation, and subsequently for full-featured CBIR. In addition, a unique CBIR-benchmark was developed (Van den Broek et al., 2004, 2005). This benchmark was used to explore what and how several parameters (e.g., color and distance measures) of the CBIR process influence retrieval results. In contrast with other research, users judgements were assigned as metric. The online IR and CBIR system Multimedia for Art Retrieval (M4ART) (URL: http://www.m4art.org) has been (partly) founded on the techniques discussed in this thesis. References: - Broek, E.L. van den, Kisters, P.M.F., and Vuurpijl, L.G. (2004). The utilization of human color categorization for content-based image retrieval. Proceedings of SPIE (Human Vision and Electronic Imaging), 5292, 351-362. [see also Chapter 7] - Broek, E.L. van den, Kisters, P.M.F., and Vuurpijl, L.G. (2005). Content-Based Image Retrieval Benchmarking: Utilizing Color Categories and Color Distributions. Journal of Imaging Science and Technology, 49(3), 293-301. [see also Chapter 8] - Broek, E.L. van den, Schouten, Th.E., and Kisters, P.M.F. (2008). Modeling Human Color Categorization. Pattern Recognition Letters, 29(8), 1136-1144. [see also Chapter 5] - Schouten, Th.E. and Broek, E.L. van den (2004). Fast Exact Euclidean Distance (FEED) transformation. In J. Kittler, M. Petrou, and M. Nixon (Eds.), Proceedings of the 17th IEEE International Conference on Pattern Recognition (ICPR 2004), Vol 3, p. 594-597. August 23-26, Cambridge - United Kingdom. [see also Appendix C

Recuperação de informação multimodal em repositórios de imagem médica

The proliferation of digital medical imaging modalities in hospitals and other diagnostic facilities has created huge repositories of valuable data, often not fully explored. Moreover, the past few years show a growing trend of data production. As such, studying new ways to index, process and retrieve medical images becomes an important subject to be addressed by the wider community of radiologists, scientists and engineers. Content-based image retrieval, which encompasses various methods, can exploit the visual information of a medical imaging archive, and is known to be beneficial to practitioners and researchers. However, the integration of the latest systems for medical image retrieval into clinical workflows is still rare, and their effectiveness still show room for improvement. This thesis proposes solutions and methods for multimodal information retrieval, in the context of medical imaging repositories. The major contributions are a search engine for medical imaging studies supporting multimodal queries in an extensible archive; a framework for automated labeling of medical images for content discovery; and an assessment and proposal of feature learning techniques for concept detection from medical images, exhibiting greater potential than feature extraction algorithms that were pertinently used in similar tasks. These contributions, each in their own dimension, seek to narrow the scientific and technical gap towards the development and adoption of novel multimodal medical image retrieval systems, to ultimately become part of the workflows of medical practitioners, teachers, and researchers in healthcare.A proliferação de modalidades de imagem médica digital, em hospitais, clínicas e outros centros de diagnóstico, levou à criação de enormes repositórios de dados, frequentemente não explorados na sua totalidade. Além disso, os últimos anos revelam, claramente, uma tendência para o crescimento da produção de dados. Portanto, torna-se importante estudar novas maneiras de indexar, processar e recuperar imagens médicas, por parte da comunidade alargada de radiologistas, cientistas e engenheiros. A recuperação de imagens baseada em conteúdo, que envolve uma grande variedade de métodos, permite a exploração da informação visual num arquivo de imagem médica, o que traz benefícios para os médicos e investigadores. Contudo, a integração destas soluções nos fluxos de trabalho é ainda rara e a eficácia dos mais recentes sistemas de recuperação de imagem médica pode ser melhorada. A presente tese propõe soluções e métodos para recuperação de informação multimodal, no contexto de repositórios de imagem médica. As contribuições principais são as seguintes: um motor de pesquisa para estudos de imagem médica com suporte a pesquisas multimodais num arquivo extensível; uma estrutura para a anotação automática de imagens; e uma avaliação e proposta de técnicas de representation learning para deteção automática de conceitos em imagens médicas, exibindo maior potencial do que as técnicas de extração de features visuais outrora pertinentes em tarefas semelhantes. Estas contribuições procuram reduzir as dificuldades técnicas e científicas para o desenvolvimento e adoção de sistemas modernos de recuperação de imagem médica multimodal, de modo a que estes façam finalmente parte das ferramentas típicas dos profissionais, professores e investigadores da área da saúde.Programa Doutoral em Informátic

Fast embedding for image classification & retrieval and its application to the hostel industry

This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University LondonContent-based image classification and retrieval are the automatic processes of taking an unseen image input and extracting its features representing the input image. Then, for the classification task, this mathematically measured input is categorized according to established criteria in the server and consequently shows the output as a result. On the other hand, for the retrieval task, the extracted features of an unseen query image are sent to the server to search for the most visually similar images to a given image and retrieve these images as a result. Despite image features could be represented by classical features, artificial intelligence-based features, Convolutional Neural Networks (CNN) to be precise, have become powerful tools in the field. Nonetheless, the high dimensional CNN features have been a challenge in particular for applications on mobile or Internet of Things devices. Therefore, in this thesis, several fast embeddings are explored and proposed to overcome the constraints of low memory, bandwidth, and power. Furthermore, the first hostel image database is created with three datasets, hostel image dataset containing 13,908 interior and exterior images of hostels across the world, and Hostels-900 dataset and Hostels-2K dataset containing 972 images and 2,380 images, respectively, of 20 London hostel buildings. The results demonstrate that the proposed fast embeddings such as the application of GHM-Rand operator, GHM-Fix operator, and binary feature vectors are able to outperform or give competitive results to those state-of-the-art methods with a lot less computational resource. Additionally, the findings from a ten-year literature review of CBIR study in the tourism industry could picturize the relevant research activities in the past decade which are not only beneficial to the hostel industry or tourism sector but also to the computer science and engineering research communities for the potential real-life applications of the existing and developing technologies in the field

Automated Semantic Content Extraction from Images

In this study, an automatic semantic segmentation and object recognition methodology is implemented which bridges the semantic gap between low level features of image content and high level conceptual meaning. Semantically understanding an image is essential in modeling autonomous robots, targeting customers in marketing or reverse engineering of building information modeling in the construction industry. To achieve an understanding of a room from a single image we proposed a new object recognition framework which has four major components: segmentation, scene detection, conceptual cueing and object recognition. The new segmentation methodology developed in this research extends Felzenswalb\u27s cost function to include new surface index and depth features as well as color, texture and normal features to overcome issues of occlusion and shadowing commonly found in images. Adding depth allows capturing new features for object recognition stage to achieve high accuracy compared to the current state of the art. The goal was to develop an approach to capture and label perceptually important regions which often reflect global representation and understanding of the image. We developed a system by using contextual and common sense information for improving object recognition and scene detection, and fused the information from scene and objects to reduce the level of uncertainty. This study in addition to improving segmentation, scene detection and object recognition, can be used in applications that require physical parsing of the image into objects, surfaces and their relations. The applications include robotics, social networking, intelligence and anti-terrorism efforts, criminal investigations and security, marketing, and building information modeling in the construction industry. In this dissertation a structural framework (ontology) is developed that generates text descriptions based on understanding of objects, structures and the attributes of an image

Multi modal multi-semantic image retrieval

PhDThe rapid growth in the volume of visual information, e.g. image, and video can overwhelm users’ ability to find and access the specific visual information of interest to them. In recent years, ontology knowledge-based (KB) image information retrieval techniques have been adopted into in order to attempt to extract knowledge from these images, enhancing the retrieval performance. A KB framework is presented to promote semi-automatic annotation and semantic image retrieval using multimodal cues (visual features and text captions). In addition, a hierarchical structure for the KB allows metadata to be shared that supports multi-semantics (polysemy) for concepts. The framework builds up an effective knowledge base pertaining to a domain specific image collection, e.g. sports, and is able to disambiguate and assign high level semantics to ‘unannotated’ images. Local feature analysis of visual content, namely using Scale Invariant Feature Transform (SIFT) descriptors, have been deployed in the ‘Bag of Visual Words’ model (BVW) as an effective method to represent visual content information and to enhance its classification and retrieval. Local features are more useful than global features, e.g. colour, shape or texture, as they are invariant to image scale, orientation and camera angle. An innovative approach is proposed for the representation, annotation and retrieval of visual content using a hybrid technique based upon the use of an unstructured visual word and upon a (structured) hierarchical ontology KB model. The structural model facilitates the disambiguation of unstructured visual words and a more effective classification of visual content, compared to a vector space model, through exploiting local conceptual structures and their relationships. The key contributions of this framework in using local features for image representation include: first, a method to generate visual words using the semantic local adaptive clustering (SLAC) algorithm which takes term weight and spatial locations of keypoints into account. Consequently, the semantic information is preserved. Second a technique is used to detect the domain specific ‘non-informative visual words’ which are ineffective at representing the content of visual data and degrade its categorisation ability. Third, a method to combine an ontology model with xi a visual word model to resolve synonym (visual heterogeneity) and polysemy problems, is proposed. The experimental results show that this approach can discover semantically meaningful visual content descriptions and recognise specific events, e.g., sports events, depicted in images efficiently. Since discovering the semantics of an image is an extremely challenging problem, one promising approach to enhance visual content interpretation is to use any associated textual information that accompanies an image, as a cue to predict the meaning of an image, by transforming this textual information into a structured annotation for an image e.g. using XML, RDF, OWL or MPEG-7. Although, text and image are distinct types of information representation and modality, there are some strong, invariant, implicit, connections between images and any accompanying text information. Semantic analysis of image captions can be used by image retrieval systems to retrieve selected images more precisely. To do this, a Natural Language Processing (NLP) is exploited firstly in order to extract concepts from image captions. Next, an ontology-based knowledge model is deployed in order to resolve natural language ambiguities. To deal with the accompanying text information, two methods to extract knowledge from textual information have been proposed. First, metadata can be extracted automatically from text captions and restructured with respect to a semantic model. Second, the use of LSI in relation to a domain-specific ontology-based knowledge model enables the combined framework to tolerate ambiguities and variations (incompleteness) of metadata. The use of the ontology-based knowledge model allows the system to find indirectly relevant concepts in image captions and thus leverage these to represent the semantics of images at a higher level. Experimental results show that the proposed framework significantly enhances image retrieval and leads to narrowing of the semantic gap between lower level machinederived and higher level human-understandable conceptualisation