Versatile Data Acquisition and Controls for Epics Using Vme-Based Fpgas

Field-Programmable Gate Arrays (FPGAs) have provided Thomas Jefferson National Accelerator Facility (Jefferson Lab) with versatile VME-based data acquisition and control interfaces with minimal development times. FPGA designs have been used to interface to VME and provide control logic for numerous systems. The building blocks of these logic designs can be tailored to the individual needs of each system and provide system operators with read-backs and controls via a VME interface to an EPICS based computer. This versatility allows the system developer to choose components and define operating parameters and options that are not readily available commercially. Jefferson Lab has begun developing standard FPGA libraries that result in quick turn around times and inexpensive designs.Comment: 3 pages, ICALEPCS 2001, T. Allison and R. Foold, Jefferson La

Ring oscillator clocks and margins

How much margin do we have to add to the delay lines of a bundled-data circuit? This paper is an attempt to give a methodical answer to this question, taking into account all sources of variability and the existing EDA machinery for timing analysis and sign-off. The paper is based on the study of the margins of a ring oscillator that substitutes a PLL as clock generator. A timing model is proposed that shows that a 12% margin for delay lines can be sufficient to cover variability in a 65nm technology. In a typical scenario, performance and energy improvements between 15% and 35% can be obtained by using a ring oscillator instead of a PLL. The paper concludes that a synchronous circuit with a ring oscillator clock shows similar benefits in performance and energy as those of bundled-data asynchronous circuits.Peer ReviewedPostprint (author's final draft

Computing centroids in current-mode technique

A novel current-mode circuit for calculating the centre of mass of a discrete distribution of currents is described. It is simple and compact, an ideal building block for VLSI analogue IC design. The design principles are presented as well as the simulated behaviour of a one-dimensional implementation

Analog and Mixed Signal Verification

More and more electronic systems have components that are not purely digital. Verification of such systems is a much less developed discipline than the digital equivalents and the application of formal (mathematically complete) techniques is a nascent area. In this paper, we will discuss the nature of analog circuit design and describe the way verification is done in practice today. We will describe some “formal” approaches coming from the analog design community. We will describe some of the approaches to formal verification that have been presented in recent literature. Finally, we will mention some areas where there are opportunities for future work

Low-Jitter Clock Multiplication: a Comparioson between PLLs and DLLs

This paper shows that, for a given power budget, a practical phase-locked loop (PLL)-based clock multiplier generates less jitter than a delay-locked loop (DLL) equivalent. This is due to the fact that the delay cells in a PLL ring-oscillator can consume more power per cell than their counterparts in the DLL. We can show that this effect is stronger than the notorious jitter accumulation effect that occurs in the voltage-controlled oscillator (VCO) of a PLL. First, an analysis of the stochastic-output jitter of the architectures, due to the most important noise sources, is presented. Then, another important source of jitter in a DLL-based clock multiplier is treated, namely the stochastic mismatch in the delay cells which compose the DLL voltage-controlled delay line (VCDL). An analysis is presented that relates the stochastic spread of the delay of the cells to the output jitter of the clock multiplier. A circuit design technique, called impedance level scaling, is then presented which allows the designer to optimize the noise and mismatch behavior of a circuit, independently from other specifications such as speed and linearity. Applying this technique on a delay cell design yields a direct tradeoff between noise induced jitter and power usage, and between stochastic mismatch induced jitter and power usage

Microsemi RTG4 Rev C Field Programmable Gate Array Single Event Effects (SEE) Heavy-Ion Test Report

The goal of this study was to perform an independent investigation of single event destructive and transient susceptibility of the Microsemi RTG4 device. The devices under test were the Microsemi RTG4 field programmable gate array (FPGA) Rev C. The devices under test will be referenced as the DUT or RTG4 Rev C throughout this document. The DUT was configured to have various test structures that are geared to measure specific potential susceptibilities of the device. DesignDevice susceptibility was determined by monitoring the DUT for Single Event Transient (SET) and Single Event Upset (SEU) induced faults by exposing the DUT to a heavy ion beam. Potential Single Event Latch-up (SEL) was checked throughout heavy-ion testing by monitoring device current

Energy Efficient Loop Unrolling for Low-Cost FPGAs

Many embedded applications implement block ciphers and sorting and searching algorithms which use multiple loop iterations for computation. These applications often demand low power operation. The power consumption of designs varies with the implementation choices made by designers. The sequential implementation of loop operations consumes minimal area, but latency and clock power are high. Alternatively, loop unrolling causes high glitch power. In this work, we propose a low area overhead approach for unrolling loop iterations that exhibits reduced glitch power. A latch based glitch filter is introduced that reduces the propagation of glitches from one iteration to next. We explore the optimal number of filters to be inserted for different applications that give a good balance between area and power. We also implement partial unrolling with glitch filters. This approach consumes less area while still giving energy savings comparable to the fully unrolled implementation. Our approach is targeted to Xilinx and Altera FPGAs. We simulate different implementation choices and compare energy results to evaluate the savings. We demonstrate our approach on SIMON-128 and AES-256 block ciphers and a sorting algorithm. We prototype our design on Xilinx Artix-7 and Altera Cyclone-IV-GX FPGA development boards and measure the actual power savings. Results show up-to 90% dynamic energy reduction in Xilinx designs, and 97% reduction in Altera designs with our glitch filtering approach due to glitch power reduction

Microfluidic Platform for Adherent Single Cell High-Throughput Screening

This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.Traditionally, in vitro investigations on biology and physiology of cells rely on averaging the responses eliciting from heterogeneous cell populations, thus being unsuitable for assessing individual cell behaviors in response to external stimulations. In the last years, great interest has thus been focused on single cell analysis and screening, which represents a promising tool aiming at pursuing the direct and deterministic control over cause-effect relationships guiding cell behavior. In this regard, a high-throughput microfluidic platform for trapping and culturing adherent single cells was presented. A single cell trapping mechanism was implemented based on dynamic variation of fluidic resistances. A round-shaped culture chamber (Φ=250μm, h=25μm) was conceived presenting two connections with a main fluidic path: (i) an upper wide opening, and (ii) a bottom trapping junction which modulates the hydraulic resistance. Several layouts of the chamber were designed and computationally validated for the optimization of the single cell trapping efficacy. The optimized chamber layouts were integrated in a polydimethylsiloxane (PDMS) microfluidic platform presenting two main functionalities: (i) 288 chambers for trapping single cells, and (ii) a chaoticmixer based serial dilution generator for delivering both soluble factors and non-diffusive molecules under spatio-temporally controlled chemical patterns. The devices were experimentally validated and allowed for trapping individual U87-MG (human glioblastoma-astrocytoma epithelial-like) cells and culturing them up to 3 days