Deep learning cardiac motion analysis for human survival prediction

Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient representations of high-dimensional motion trajectories so that these can be used for prediction tasks. Here we use image sequences of the heart, acquired using cardiac magnetic resonance imaging, to create time-resolved three-dimensional segmentations using a fully convolutional network trained on anatomical shape priors. This dense motion model formed the input to a supervised denoising autoencoder (4Dsurvival), which is a hybrid network consisting of an autoencoder that learns a task-specific latent code representation trained on observed outcome data, yielding a latent representation optimised for survival prediction. To handle right-censored survival outcomes, our network used a Cox partial likelihood loss function. In a study of 302 patients the predictive accuracy (quantified by Harrell's C-index) was significantly higher (p < .0001) for our model C=0.73 (95$\%$ CI: 0.68 - 0.78) than the human benchmark of C=0.59 (95$\%$ CI: 0.53 - 0.65). This work demonstrates how a complex computer vision task using high-dimensional medical image data can efficiently predict human survival

To Normalize, or Not to Normalize: The Impact of Normalization on Part-of-Speech Tagging

Does normalization help Part-of-Speech (POS) tagging accuracy on noisy, non-canonical data? To the best of our knowledge, little is known on the actual impact of normalization in a real-world scenario, where gold error detection is not available. We investigate the effect of automatic normalization on POS tagging of tweets. We also compare normalization to strategies that leverage large amounts of unlabeled data kept in its raw form. Our results show that normalization helps, but does not add consistently beyond just word embedding layer initialization. The latter approach yields a tagging model that is competitive with a Twitter state-of-the-art tagger.Comment: In WNUT 201

Patient-adapted and inter-patient ecg classification using neural network and gradient boosting

Heart disease diagnosis is an important non-invasive technique. Therefore, there exists an effort to increase the accuracy of arrhythmia classification based on ECG signals. In this work, we present a novel approach of heart arrhythmia detection. The model consists of two parts. The first part extracts important features from raw ECG signal using Auto-Encoder Neural Network. Extracted features obtained by Auto-Encoder represent an input for the second part of the model, the Gradient Boosting and Feedforward Neural Network classifiers. For comparison purposes, we evaluated our approach by using MIT-BIH ECG database and also following recommendations of the Association for the Advancement of Medical Instrumentation (AAMI) for ECG class labeling. We divided our experiment into two scenarios. The first scenario represents the classification task for the patient-adapted paradigm and the second one was dedicated to the inter-patient paradigm. We compared the measured results to the state-of-the-art methods and it shows that our method outperforms the state-of-the art methods in the Ventricular Ectopic (VEB) class for both paradigms and Supraventricular Ectopic (SVEB) class in the inter-patient paradigm.Web of Science28325424

Improving Neural Network Performance with Feature Selection Using Pearson Correlation Method for Diabetes Disease Detection

Diabetic or silent killer diseases are an alarming scourge for the world and are classed as serious diseases. In Indonesia, the increase in diabetics occurred by 2% in vulnerable times between 2013 to 2018. This affects all sectors, both medical services and the financial sector. The Neural Network method as a data mining algorithm is present to overcome the burden that arises as an early detection analysis of the onset of disease. However, Neural Network has slow training capabilities and can identify important attributes in the data resulting in a decrease in performance. Pearson correlation is good at handling data with mixed-type attributes and is good at measuring information between attributes and attributes with labels. With this, the purpose of this study will be to use the Pearson correlation method as a selection of features to improve neural network performance in diabetes detection and measure the extent of accuracy obtained from the method. The dataset used is diabetes data 130-US hospital UCI with a record number of 101767 and the number of attributes as many as 50 attributes. The results of this study found that Pearson correlation can improve neural network accuracy performance from 94.93% to 96.00%. As for the evaluation results on the AUC value increased from 0.8077 to 0.8246. Thus Pearson's Correlation algorithm can work well for feature selection on neural network methods and can provide solutions to improved diabetes detection accuracy

Spatio-temporal learning with the online finite and infinite echo-state Gaussian processes

Successful biological systems adapt to change. In this paper, we are principally concerned with adaptive systems that operate in environments where data arrives sequentially and is multivariate in nature, for example, sensory streams in robotic systems. We contribute two reservoir inspired methods: 1) the online echostate Gaussian process (OESGP) and 2) its infinite variant, the online infinite echostate Gaussian process (OIESGP) Both algorithms are iterative fixed-budget methods that learn from noisy time series. In particular, the OESGP combines the echo-state network with Bayesian online learning for Gaussian processes. Extending this to infinite reservoirs yields the OIESGP, which uses a novel recursive kernel with automatic relevance determination that enables spatial and temporal feature weighting. When fused with stochastic natural gradient descent, the kernel hyperparameters are iteratively adapted to better model the target system. Furthermore, insights into the underlying system can be gleamed from inspection of the resulting hyperparameters. Experiments on noisy benchmark problems (one-step prediction and system identification) demonstrate that our methods yield high accuracies relative to state-of-the-art methods, and standard kernels with sliding windows, particularly on problems with irrelevant dimensions. In addition, we describe two case studies in robotic learning-by-demonstration involving the Nao humanoid robot and the Assistive Robot Transport for Youngsters (ARTY) smart wheelchair

Blood pressure waveform characteristics exposed by spectral analysis and neural nets

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