21 research outputs found

    Genetic programming

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    REVERSE ENGINEERING OF METABOLIC PATHWAYS FROM OBSERVED DATA USING GENETIC PROGRAMMING

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    "Going back to our roots": second generation biocomputing

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    Researchers in the field of biocomputing have, for many years, successfully "harvested and exploited" the natural world for inspiration in developing systems that are robust, adaptable and capable of generating novel and even "creative" solutions to human-defined problems. However, in this position paper we argue that the time has now come for a reassessment of how we exploit biology to generate new computational systems. Previous solutions (the "first generation" of biocomputing techniques), whilst reasonably effective, are crude analogues of actual biological systems. We believe that a new, inherently inter-disciplinary approach is needed for the development of the emerging "second generation" of bio-inspired methods. This new modus operandi will require much closer interaction between the engineering and life sciences communities, as well as a bidirectional flow of concepts, applications and expertise. We support our argument by examining, in this new light, three existing areas of biocomputing (genetic programming, artificial immune systems and evolvable hardware), as well as an emerging area (natural genetic engineering) which may provide useful pointers as to the way forward.Comment: Submitted to the International Journal of Unconventional Computin

    Improved model reduction and tuning of fractional-order PI(位)D(渭) controllers for analytical rule extraction with genetic programming

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    This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Genetic algorithm (GA) has been used in this study for a new approach of suboptimal model reduction in the Nyquist plane and optimal time domain tuning of proportional-integral-derivative (PID) and fractional-order (FO) PI(位)D(渭) controllers. Simulation studies show that the new Nyquist-based model reduction technique outperforms the conventional H(2)-norm-based reduced parameter modeling technique. With the tuned controller parameters and reduced-order model parameter dataset, optimum tuning rules have been developed with a test-bench of higher-order processes via genetic programming (GP). The GP performs a symbolic regression on the reduced process parameters to evolve a tuning rule which provides the best analytical expression to map the data. The tuning rules are developed for a minimum time domain integral performance index described by a weighted sum of error index and controller effort. From the reported Pareto optimal front of the GP-based optimal rule extraction technique, a trade-off can be made between the complexity of the tuning formulae and the control performance. The efficacy of the single-gene and multi-gene GP-based tuning rules has been compared with the original GA-based control performance for the PID and PI(位)D(渭) controllers, handling four different classes of representative higher-order processes. These rules are very useful for process control engineers, as they inherit the power of the GA-based tuning methodology, but can be easily calculated without the requirement for running the computationally intensive GA every time. Three-dimensional plots of the required variation in PID/fractional-order PID (FOPID) controller parameters with reduced process parameters have been shown as a guideline for the operator. Parametric robustness of the reported GP-based tuning rules has also been shown with credible simulation examples.This work has been supported by the Department of Science and Technology (DST), Government of India, under the PURSE programme

    Hoare Logic-based Genetic Programming

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    Almost all existing genetic programming systems deal with fitness evaluation solely by testing. In this paper, by contrast, we present an original approach that combines genetic programming with Hoare logic with the aid of model checking and finite state automata, henceby proposing a brand new verification-focused formal genetic programming system that makes it possible to evolve reliable programs with mathematically-verified properties

    The Software Continuum Concept: Towards a Biologically Inspired Model for Robust E-Business Software Automation

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    This paper introduces a new concept, the software continuum concept based on the observation that exists a general parallelism between the software continuum from bits to business/Internet ecosystems and the natural continuum from particles to ecosystems. The general parallelism suggests that homeomorphisms may be identified and therefore some concepts, processes, and/or mechanisms in one continuum can be investigated for application in the other continuum. We argue that the homeomorphisms give rise to a biologically-inspired architectural framework for addressing robust control, robust intelligence, and robust autonomy issues in e-business software and other business-IT integration challenges. As application, we examine the mapping of a major enterprise-level architecture framework to the biologically-inspired framework. Design considerations for robust intelligence and autonomy in large-scale software automation and some major systemic features for flexible business-IT integration are also discussed
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