低コスト・低被ばくポータブルX線肺機能イメージング（診る聴診器）の開発

Dynamic chest radiography with computer analysis is expected to be a new type of functional imaging system, which can quantify and visualize cardiopulmonary function on dynamic chest radiographs, such as diaphragm motion, heart wall motion, pulmonary ventilation, and blood circulation. We will first introduce the backgraound, imaging methods, and then image analysis methods for each evaluation item. We pay particular attention to interframe subtraction and mapping technique, which play a critical role in the evaluation of pulmonary ventilation and blood circulation. We also discuss features, future perspectives, and issues related to dynamic chest radiography on the basis of preliminary clinical study

Imaging of the Breast

Early detection of breast cancer combined with targeted therapy offers the best outcome for breast cancer patients. This volume deal with a wide range of new technical innovations for improving breast cancer detection, diagnosis and therapy. There is a special focus on improvements in mammographic image quality, image analysis, magnetic resonance imaging of the breast and molecular imaging. A chapter on targeted therapy explores the option of less radical postoperative therapy for women with early, screen-detected breast cancers

Application of a High‑Resolution Computed Radiography System in Detecting an Iodinated X‑ray Contrast Agent: Small Animal Phantom Study

Tumor angiogenesis, the creation of new blood vessels, is the characteristic of solid tumors and crucial for their development. Iodinated contrast agents are used to increase the X‑ray detectability of zone of angiogenesis, and thus providing a means for tracking tumor growth. The overall objective of this project was to evaluate the performance of Kodak CR 7400, a high‑resolution compact computed radiography (CR) system in detection of Omnipaque‑240, an iodinated contrast agent, in a phantom mimicking small animal tumor model. The first phase of the project was dedicated to a comprehensive assessment of CR image quality by measuring presampled Modulation Transfer Function (MTF), Noise Power Spectrum (NPS), Relative Standard Deviation of Noise (RSD), Noise Equivalent Quanta (NEQ), and Detective Quantum Efficiency (DQE). Next, dual‑energy and temporal subtraction techniques were implemented to enhance the contrast of iodinated regions and suppress soft tissue background in the phantom. The underlying physics of each technique was discussed, including the design of the phantoms, the simulation and measurement of the Signal‑to‑Noise Ratio (SNR) in the final subtracted iodine image, and dose assessment. In the end, the results of both techniques were compared along with discussions about the advantages and limitations of implementing each technique. Overall, the study supported the potential of low‑cost CR 7400 in small animal study, particularly detecting iodinated contrast agents implementing temporal subtraction technique and provided a background for similar small animal studies using a CR system

Diseases of the Chest, Breast, Heart and Vessels 2019-2022

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology

Diseases of the Chest, Breast, Heart and Vessels 2019-2022

This open access book focuses on diagnostic and interventional imaging of the chest, breast, heart, and vessels. It consists of a remarkable collection of contributions authored by internationally respected experts, featuring the most recent diagnostic developments and technological advances with a highly didactical approach. The chapters are disease-oriented and cover all the relevant imaging modalities, including standard radiography, CT, nuclear medicine with PET, ultrasound and magnetic resonance imaging, as well as imaging-guided interventions. As such, it presents a comprehensive review of current knowledge on imaging of the heart and chest, as well as thoracic interventions and a selection of "hot topics". The book is intended for radiologists, however, it is also of interest to clinicians in oncology, cardiology, and pulmonology