Quality control improvement at Jana DCS Sdn. Bhd.

Jana DCS Sdn. Bhd. is one of the companies that run the service of air conditioning system supply in Nusajaya, Johor, Malaysia. Quality improvement is one of the most important part when talking about a company, mostly companies that operate in service industries. Quality control plays the major parts in quality improvement as quality control is an operational technique to ensure efficient and effective operation. Roughly, total net area cooled by Jana DCS Sdn. Bhd. is 590,000 square feet as for Johor State Government Administration Centre. While for Puteri Harbour, the total net area cooled is 614,000 square feet. Jana DCS Sdn. Bhd. operates Iskandar Malaysia’s first district cooling plant, with both thermal energy and chilled water storage capability that produce and supply cooling load for air conditioning to the Johor State Government Complex at Kota Iskandar and to various private sector developments at Puteri Harbour

Whole-brain vasculature reconstruction at the single capillary level

The distinct organization of the brain’s vascular network ensures that it is adequately supplied with oxygen and nutrients. However, despite this fundamental role, a detailed reconstruction of the brain-wide vasculature at the capillary level remains elusive, due to insufficient image quality using the best available techniques. Here, we demonstrate a novel approach that improves vascular demarcation by combining CLARITY with a vascular staining approach that can fill the entire blood vessel lumen and imaging with light-sheet fluorescence microscopy. This method significantly improves image contrast, particularly in depth, thereby allowing reliable application of automatic segmentation algorithms, which play an increasingly important role in high-throughput imaging of the terabyte-sized datasets now routinely produced. Furthermore, our novel method is compatible with endogenous fluorescence, thus allowing simultaneous investigations of vasculature and genetically targeted neurons. We believe our new method will be valuable for future brain-wide investigations of the capillary network

Histopathological image analysis : a review

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe

Rede neural convolucional eficiente para detecção e contagem dos glóbulos sanguíneos

Blood cell analysis is an important part of the health and immunity assessment. There are three major components of the blood: red blood cells, white blood cells, and platelets. The count and density of these blood cells are used to find multiple disorders like blood infections (anemia, leukemia, among others). Traditional methods are time-consuming, and the test cost is high. Thus, it arises the need for automated methods that can detect different kinds of blood cells and count the number of cells. A convolutional neural network-based framework is proposed for detecting and counting the cells. The neural network is trained for the multiple iterations, and a model having lower validation loss is saved. The experiments are done to analyze the performance of the detection system and results with high accuracy in the counting of the cells. The mean average precision is achieved when compared to ground truth provided to respective labels. The value of the average precision is found to be ranging from 70% to 99.1%, with a mean average precision value of 85.35%. The proposed framework had much less time complexity: it took only 0.111 seconds to process an image frame with dimensions of 640×480 pixels. The system can also be implemented in low-cost, single-board computers for rapid prototyping. The efficiency of the proposed framework to identify and count different blood cells can be utilized to assist medical professionals in finding disorders and making decisions based on the obtained report.El análisis de células sanguíneas es una parte importante de la evaluación de la salud y la inmunidad. Hay tres componentes principales de los glóbulos rojos, los glóbulos blancos y las plaquetas. El recuento y la densidad de estas células sanguíneas se utilizan para encontrar múltiples trastornos como infecciones de la sangre como anemia, leucemia, etc. Los métodos tradicionales consumen mucho tiempo y el costo de las pruebas es alto. Por tanto, surge la necesidad de métodos automatizados que puedan detectar diferentes tipos de células sanguíneas y contar el número de células. Se propone un marco basado en una red neuronal convolucional para la detección y el recuento de las células. La red neuronal se entrena para las múltiples iteraciones y se guarda un modelo que tiene una menor pérdida de validación. Los experimentos se realizan con el fin de analizar el rendimiento del sistema de detección y los resultados con alta precisión en el recuento de células. La precisión promedio se logra al analizar las respectivas etiquetas que hay en la imagen. Se ha determinado que el valor de la precisión promedio, oscila entre el 70% y el 99,1% con un valor medio de 85,35%. El coste computacional de la propuesta fue de 0.111 segundos, procesar una imagen con dimensiones de 640 × 480 píxeles. El sistema también se puede implementar en ordenadores con CPU de bajo costo, para la creación rápida de prototipos. La eficiencia de la propuesta, para identificar y contar diferentes células sanguíneas, se puede utilizar para ayudar a los profesionales médicos a encontrar los trastornos y la toma decisiones, a partir de la identificación automática.O exame de células sanguíneas é uma parte importante da avaliação de saúde e imunidade. Há três componentes principais dos glóbulos vermelhos, glóbulos brancos e plaquetas. A contagem e a densidade dessas células sanguíneas são usadas para encontrar múltiplos distúrbios, tais como infecções no sangue: anemia, leucemia, etc. Os métodos tradicionais são demorados e o custo dos testes é alto. Portanto, surge a necessidade de métodos automatizados que possam detectar diferentes tipos de células sanguíneas e contar o número de células. É proposta uma estrutura baseada em rede neural convolucional para a detecção e contagem de células. A rede neural é treinada para múltiplas iterações e é salvo um modelo que tem uma menor perda de validação. São realizados experimentos para analisar o desempenho do sistema de detecção e os resultados com alta precisão na contagem de células. A precisão média é obtida analisando os respectivos rótulos na imagem. Foi determinado que o valor médio de precisão oscila entre 70 % e 99,1 % com um valor médio de 85,35 %. O custo computacional da proposta foi de 0,111 segundos, processando uma imagem com dimensões de 640 × 480 pixels. O sistema também pode ser implementado em computadores com CPUs de baixo custo para prototipagem rápida. A eficiência da proposta, para identificar e contar diferentes células sanguíneas, pode ser usada para ajudar os profissionais médicos a encontrar distúrbios e tomar decisões, com base na identificação automática

A Review on Classification of White Blood Cells Using Machine Learning Models

The machine learning (ML) and deep learning (DL) models contribute to exceptional medical image analysis improvement. The models enhance the prediction and improve the accuracy by prediction and classification. It helps the hematologist to diagnose the blood cancer and brain tumor based on calculations and facts. This review focuses on an in-depth analysis of modern techniques applied in the domain of medical image analysis of white blood cell classification. For this review, the methodologies are discussed that have used blood smear images, magnetic resonance imaging (MRI), X-rays, and similar medical imaging domains. The main impact of this review is to present a detailed analysis of machine learning techniques applied for the classification of white blood cells (WBCs). This analysis provides valuable insight, such as the most widely used techniques and best-performing white blood cell classification methods. It was found that in recent decades researchers have been using ML and DL for white blood cell classification, but there are still some challenges. 1) Availability of the dataset is the main challenge, and it could be resolved using data augmentation techniques. 2) Medical training of researchers is recommended to help them understand the structure of white blood cells and select appropriate classification models. 3) Advanced DL networks such as Generative Adversarial Networks, R-CNN, Fast R-CNN, and faster R-CNN can also be used in future techniques.Comment: 23 page

Flow velocity mapping using contrast enhanced high-frame-rate plane wave ultrasound and image tracking: methods and initial in vitro and in vivo evaluation

Ultrasound imaging is the most widely used method for visualising and quantifying blood flow in medical practice, but existing techniques have various limitations in terms of imaging sensitivity, field of view, flow angle dependence, and imaging depth. In this study, we developed an ultrasound imaging velocimetry approach capable of visualising and quantifying dynamic flow, by combining high-frame-rate plane wave ultrasound imaging, microbubble contrast agents, pulse inversion contrast imaging and speckle image tracking algorithms. The system was initially evaluated in vitro on both straight and carotid-mimicking vessels with steady and pulsatile flows and in vivo in the rabbit aorta. Colour and spectral Doppler measurements were also made. Initial flow mapping results were compared with theoretical prediction and reference Doppler measurements and indicate the potential of the new system as a highly sensitive, accurate, angle-independent and full field-of-view velocity mapping tool capable of tracking and quantifying fast and dynamic flows

A Review on Methods of Identifying and Counting Aedes Aegypti Larvae using Image Segmentation Technique

Aedes aegypti mosquitoes are a small slender fly insect that spreads the arbovirus from flavivirus vector through its sucking blood. An early detection of this species is very important because once these species turn into adult mosquitoes a population control becomes more complicated. Things become worse when difficult access places like water storage tank becomes one of the breeding favorite places for Aedes aegypti mosquitoes. Therefore, there is a need to help the field operator during the routine inspection for an automated identification and detection of Aedes aegypti larvae, especially at difficult access places. This paper reviews different methodologies that have been used by various researchers in identifying and counting Aedes aegypti. The objective of the review was to analyze the techniques and methods in identifying and counting the Aedes Aegypti larvae of various fields of study from 2008 and above by taking account their performance and accuracy. From the review, thresholding method was the most widely used with high accuracy in image segmentation followed by hidden Markov model, histogram correction and morphology operation region growing

Performance Analysis of Cone Detection Algorithms

Many algorithms have been proposed to help clinicians evaluate cone density and spacing, as these may be related to the onset of retinal diseases. However, there has been no rigorous comparison of the performance of these algorithms. In addition, the performance of such algorithms is typically determined by comparison with human observers. Here we propose a technique to simulate realistic images of the cone mosaic. We use the simulated images to test the performance of two popular cone detection algorithms and we introduce an algorithm which is used by astronomers to detect stars in astronomical images. We use Free Response Operating Characteristic (FROC) curves to evaluate and compare the performance of the three algorithms. This allows us to optimize the performance of each algorithm. We observe that performance is significantly enhanced by up-sampling the images. We investigate the effect of noise and image quality on cone mosaic parameters estimated using the different algorithms, finding that the estimated regularity is the most sensitive parameter. This paper was published in JOSA A and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/abstract.cfm?msid=224577. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.Comment: 13 pages, 7 figures, 2 table