Slavery in Niger: Historical, legal and contemporary perspectives

This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide. Special emphasis is placed on labor rights, working conditions, labor market changes, and union organizing.ASI_2004_DBS_Niger_Slavery_in_Niger.pdf: 110 downloads, before Oct. 1, 2020

Virtual Museum for NACHA

Our team worked with the Nso’ Arts and Cultural Heritage Association and created a virtual museum in order to increase awareness of the unique culture of the Nso’ people in Cameroon, Africa. A lot of information from this region is in danger of being lost due to political tension and poor artifact conservation, and many people, including the Cameroonian youth, are not prioritizing the preservation of their culture and history. Creating a website where individuals can view the art, history, and culture found in Cameroon is the best way to increase the availability of knowledge of the Nso’ people. Such a system will not only allow individuals to become more familiar with Cameroon, but it will also allow researchers to update the site and add new information as they go deeper into their research. Since anyone with a web-enabled device will be able to access the virtual museum, it has the potential to get people from around the world, including the youth in Cameroon, interested in learning more about the art, history, and traditions native to that region

Genesis of Altmetrics or Article-level Metrics for Measuring Efficacy of Scholarly Communications: Current Perspectives

The article-level metrics (ALMs) or altmetrics becomes a new trendsetter in recent times for measuring the impact of scientific publications and their social outreach to intended audiences. The popular social networks such as Facebook, Twitter, and Linkedin and social bookmarks such as Mendeley and CiteULike are nowadays widely used for communicating research to larger transnational audiences. In 2012, the San Francisco Declaration on Research Assessment got signed by the scientific and researchers communities across the world. This declaration has given preference to the ALM or altmetrics over traditional but faulty journal impact factor (JIF)-based assessment of career scientists. JIF does not consider impact or influence beyond citations count as this count reflected only through Thomson Reuters' Web of Science database. Furthermore, JIF provides indicator related to the journal, but not related to a published paper. Thus, altmetrics now becomes an alternative metrics for performance assessment of individual scientists and their contributed scholarly publications. This paper provides a glimpse of genesis of altmetrics in measuring efficacy of scholarly communications and highlights available altmetric tools and social platforms linking altmetric tools, which are widely used in deriving altmetric scores of scholarly publications. The paper thus argues for institutions and policy makers to pay more attention to altmetrics based indicators for evaluation purpose but cautions that proper safeguards and validations are needed before their adoption

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development.

UNLABELLED: Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its natural resistance to most antibiotics, the development of new antimicrobial therapies is imperative. To identify drug targets and better understand the complex B. pseudomallei genome, we sought a genome-wide approach to identify lethal gene targets. As B. pseudomallei has an unusually large genome spread over two chromosomes, an extensive screen was required to achieve a comprehensive analysis. Here we describe transposon-directed insertion site sequencing (TraDIS) of a library of over 10(6) transposon insertion mutants, which provides the level of genome saturation required to identify essential genes. Using this technique, we have identified a set of 505 genes that are predicted to be essential in B. pseudomallei K96243. To validate our screen, three genes predicted to be essential, pyrH, accA, and sodB, and a gene predicted to be nonessential, bpss0370, were independently investigated through the generation of conditional mutants. The conditional mutants confirmed the TraDIS predictions, showing that we have generated a list of genes predicted to be essential and demonstrating that this technique can be used to analyze complex genomes and thus be more widely applied. IMPORTANCE: Burkholderia pseudomallei is a lethal human pathogen that is considered a potential bioterrorism threat and has limited treatment options due to an unusually high natural resistance to most antibiotics. We have identified a set of genes that are required for bacterial growth and thus are excellent candidates against which to develop potential novel antibiotics. To validate our approach, we constructed four mutants in which gene expression can be turned on and off conditionally to confirm that these genes are required for the bacteria to survive

Research Trends & Emerging Technologies for Genealogists

This study examines current research methods utilized by genealogists, and seeks to discover the impact of emerging tools and technologies on their information seeking needs and behaviors. When it became clear that there is a shortage of scholarly studies identifying the use of newer technologies (i.e. blogs, social media, and apps), an original survey for genealogists was created. Over four hundred genealogists were surveyed regarding their use of both traditional research methods (methods that have existed for many decades) and Internet/electronic resources, in order to demonstrate which new trends are emerging. The data from the survey might lessen the gap in current scholarly research. Technology is constantly changing, and the findings show which trends are currently being utilized the most by genealogists. The results indicate that genealogists are definitely using more technology to research their family trees. In fact, they adapt fairly quickly to new methods, relying heavily on technology and the Internet to conduct research and share information. Due to the ease of using technology, fewer and fewer genealogists rely on in-house visits to repositories to access original documents. The research concludes with a discussion on where the use of technology for genealogical research is headed, and what genealogists hope to accomplish by using new tools and technologies

Recent trends in US patent grants and issues to be considered

The life sciences have changed radically since the Convention on Biological Diversity first opened for signatures in 1992. Traditional organism-based approaches to discovery and use of genetic resources have been supplanted by molecular approaches. Biodiversity prospecting is more likely to be a programmatic bioinformatics activity rather than an activity conducted by field scientists. Access to genetic resources is no longer centered on a hunt for novel species. Rather, the hunt is for novel genes and metabolic pathways that can be cloned into well-understood expression systems and readily scaled-up for industrial production. Information about contemporary research, development, and manufacturing practices needs to be addressed, especially when those genes do not need to be associated with their native host at the time of discovery. Information about the research organizations participating in all phases of the discovery and development process also needs to be considered, especially when it involves partnerships between academic and industrial organizations. 

We present a high-level view of recent trends in the issuance of US patent grants to commercial and non-commercial research organizations, and introduce a technology that is already in place which can be applied to monitoring the use of genetic materials by various stakeholders in an open and transparent manner, as intended under the International Regime for Access and Benefit Sharing (ABS).
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Two intracellular and cell type-specific bacterial symbionts in the placozoan Trichoplax H2

Placozoa is an enigmatic phylum of simple, microscopic, marine metazoans(1,2). Although intracellular bacteria have been found in all members of this phylum, almost nothing is known about their identity, location and interactions with their host(3-6). We used metagenomic and metatranscriptomic sequencing of single host individuals, plus metaproteomic and imaging analyses, to show that the placozoan Trichoplax sp. H2 lives in symbiosis with two intracellular bacteria. One symbiont forms an undescribed genus in the Midichloriaceae (Rickettsiales)(7,8) and has a genomic repertoire similar to that of rickettsial parasites(9,10), but does not seem to express key genes for energy parasitism. Correlative image analyses and three-dimensional electron tomography revealed that this symbiont resides in the rough endoplasmic reticulum of its host's internal fibre cells. The second symbiont belongs to the Margulisbacteria, a phylum without cultured representatives and not known to form intracellular associations(11-13). This symbiont lives in the ventral epithelial cells of Trichoplax, probably metabolizes algal lipids digested by its host and has the capacity to supplement the placozoan's nutrition. Our study shows that one of the simplest animals has evolved highly specific and intimate associations with symbiotic, intracellular bacteria and highlights that symbioses can provide access to otherwise elusive microbial dark matter