Pattern Recognition

Pattern recognition is a very wide research field. It involves factors as diverse as sensors, feature extraction, pattern classification, decision fusion, applications and others. The signals processed are commonly one, two or three dimensional, the processing is done in real- time or takes hours and days, some systems look for one narrow object class, others search huge databases for entries with at least a small amount of similarity. No single person can claim expertise across the whole field, which develops rapidly, updates its paradigms and comprehends several philosophical approaches. This book reflects this diversity by presenting a selection of recent developments within the area of pattern recognition and related fields. It covers theoretical advances in classification and feature extraction as well as application-oriented works. Authors of these 25 works present and advocate recent achievements of their research related to the field of pattern recognition

A Method for Predicting Dose Changes for HN Treatment Using Surface Imaging

Head and neck cancer is commonly treated with a six- to seven-week course of radiotherapy, during which a patient’s anatomy may change substantially, due to target reduction or weight loss. Anatomical changes lead to reduction in treatment quality due to decreased setup reproducibility and altered dose deposition compared to the original plan. Few clinics have developed a standard method for triggering resimulation and replan due to anatomic changes. This work investigates a new method for determining when to resimulate and replan HNC patients by utilizing their topographic anatomical changes to predict differences in planned versus delivered dose distributions. The first part of the work presents a method for deformable image registration of CT to CBCT which addresses the challenges of inaccurate Hounsfield units and truncated field of view present in CBCT. The registration method was validated on 10 HN patients using contour comparison, with average DSC of 0.82, 0.74, 0.72, and 0.69 for mandible, cord, and left and right parotid. The registration method was then used to generate dose maps and surface contours for 47 patients for the second part of this work, the development of a U-Net which takes the original dose distribution, the original surface, and the treatment day surface as input and predicts the treatment day dose distribution as output. The average RMSE and MAE between the true and predicted dose distributions for a test set of 6 patients was 4.25 and 2.15. This work proves feasibility of a dose prediction neural network using surface imaging

Introduction to machine and deep learning for medical physicists

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/155469/1/mp14140_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155469/2/mp14140.pd

Computational Intelligence Techniques in Visual Pattern Recognition

Ph.DDOCTOR OF PHILOSOPH

Image Guided Respiratory Motion Analysis: Time Series and Image Registration.

The efficacy of Image guided radiation therapy (IGRT) systems relies on accurately extracting, modeling and predicting tumor movement with imaging techniques. This thesis investigates two key problems associated with such systems: motion modeling and image processing. For thoracic and upper abdominal tumors, respiratory motion is the dominant factor for tumor movement. We have studied several special structured time series analysis techniques to incorporate the semi-periodicity characteristics of respiratory motion. The proposed methods are robust towards large variations among fractions and populations; the algorithms perform stably in the presence of sparse radiographic observations with noise. We have proposed a subspace projection method to quantitatively evaluate the semi-periodicity of a given observation trace; a nonparametric local regression approach for real-time prediction of respiratory motion; a state augmentation scheme to model hysteresis; and an ellipse tracking algorithm to estimate the trend of respiratory motion in real time. For image processing, we have focused on designing regularizations to account for prior information in image registration problems. We investigated a penalty function design that accommodates tissue-type-dependent elasticity information. We studied a class of discontinuity preserving regularizers that yield smooth deformation estimates in most regions, yet allow discontinuities supported by data. We have further proposed a discriminate regularizer that preserves shear discontinuity, but discourages folding or vacuum generating flows. In addition, we have initiated a preliminary principled study on the fundamental performance limit of image registration problems. We proposed a statistical generative model to account for noise effect in both source and target images, and investigated the approximate performance of the maximum-likelihood estimator corresponding to the generative model and the commonly adopted M-estimator. A simple example suggests that the approximation is reasonably accurate. Our studies in both time series analysis and image registration constitute essential building-blocks for clinical applications such as adaptive treatment. Besides their theoretical interests, it is our sincere hope that with further justifications, the proposed techniques would realize its clinical value, and improve the quality of life for patients.Ph.D.Electrical Engineering: SystemsUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.lib.umich.edu/bitstream/2027.42/60673/1/druan_1.pd

Advancements and Breakthroughs in Ultrasound Imaging

Ultrasonic imaging is a powerful diagnostic tool available to medical practitioners, engineers and researchers today. Due to the relative safety, and the non-invasive nature, ultrasonic imaging has become one of the most rapidly advancing technologies. These rapid advances are directly related to the parallel advancements in electronics, computing, and transducer technology together with sophisticated signal processing techniques. This book focuses on state of the art developments in ultrasonic imaging applications and underlying technologies presented by leading practitioners and researchers from many parts of the world

Respiratory organ motion in interventional MRI : tracking, guiding and modeling

Respiratory organ motion is one of the major challenges in interventional MRI, particularly in interventions with therapeutic ultrasound in the abdominal region. High-intensity focused ultrasound found an application in interventional MRI for noninvasive treatments of different abnormalities. In order to guide surgical and treatment interventions, organ motion imaging and modeling is commonly required before a treatment start. Accurate tracking of organ motion during various interventional MRI procedures is prerequisite for a successful outcome and safe therapy. In this thesis, an attempt has been made to develop approaches using focused ultrasound which could be used in future clinically for the treatment of abdominal organs, such as the liver and the kidney. Two distinct methods have been presented with its ex vivo and in vivo treatment results. In the first method, an MR-based pencil-beam navigator has been used to track organ motion and provide the motion information for acoustic focal point steering, while in the second approach a hybrid imaging using both ultrasound and magnetic resonance imaging was combined for advanced guiding capabilities. Organ motion modeling and four-dimensional imaging of organ motion is increasingly required before the surgical interventions. However, due to the current safety limitations and hardware restrictions, the MR acquisition of a time-resolved sequence of volumetric images is not possible with high temporal and spatial resolution. A novel multislice acquisition scheme that is based on a two-dimensional navigator, instead of a commonly used pencil-beam navigator, was devised to acquire the data slices and the corresponding navigator simultaneously using a CAIPIRINHA parallel imaging method. The acquisition duration for four-dimensional dataset sampling is reduced compared to the existing approaches, while the image contrast and quality are improved as well. Tracking respiratory organ motion is required in interventional procedures and during MR imaging of moving organs. An MR-based navigator is commonly used, however, it is usually associated with image artifacts, such as signal voids. Spectrally selective navigators can come in handy in cases where the imaging organ is surrounding with an adipose tissue, because it can provide an indirect measure of organ motion. A novel spectrally selective navigator based on a crossed-pair navigator has been developed. Experiments show the advantages of the application of this novel navigator for the volumetric imaging of the liver in vivo, where this navigator was used to gate the gradient-recalled echo sequence

Fuzzy Logic

The capability of Fuzzy Logic in the development of emerging technologies is introduced in this book. The book consists of sixteen chapters showing various applications in the field of Bioinformatics, Health, Security, Communications, Transportations, Financial Management, Energy and Environment Systems. This book is a major reference source for all those concerned with applied intelligent systems. The intended readers are researchers, engineers, medical practitioners, and graduate students interested in fuzzy logic systems